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Accurate and reliable brain tumor segmentation, particularly when dealing with missing modalities, remains a critical challenge in medical image analysis. Previous studies have not fully resolved the challenges of tumor boundary…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Shenghao Zhu , Yifei Chen , Weihong Chen , Yuanhan Wang , Chang Liu , Shuo Jiang , Feiwei Qin , Changmiao Wang

Brain Tumor Segmentation from magnetic resonance imaging (MRI) is a critical technique for early diagnosis. However, rather than having complete four modalities as in BraTS dataset, it is common to have missing modalities in clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Yan Shen , Mingchen Gao

Multi-modal MRIs are widely used in neuroimaging applications since different MR sequences provide complementary information about brain structures. Recent works have suggested that multi-modal deep learning analysis can benefit from…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Jiahong Ouyang , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao , Greg Zaharchuk

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Multimodal MR images can provide complementary information for accurate brain tumor segmentation. However, it's common to have missing imaging modalities in clinical practice. Since there exists a strong correlation between multi…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Multimodal 3D MRI brain tumor segmentation is a pivotal step in radiotherapy target delineation, surgical planning and post-treatment assessment. Existing methods often assume artifact-free MRI images. However, inevitable patient motion…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Yuchun Wang , Xiaosong Li , Gefei Liang , Yang Liu

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

This technical report presents a comparative analysis of existing deep learning (DL) based approaches for brain tumor segmentation with missing MRI modalities. Approaches evaluated include the Adversarial Co-training Network (ACN) and a…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Benteng Ma , Yushi Wang , Shen Wang

Medical image segmentation plays a crucial role in computer-aided diagnosis. However, existing methods heavily rely on fully supervised training, which requires a large amount of labeled data with time-consuming pixel-wise annotations.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Yunqi Gu , Tao Zhou , Yizhe Zhang , Yi Zhou , Kelei He , Chen Gong , Huazhu Fu

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yuxiang Luo , Qing Xu , Hai Huang , Yuqi Ouyang , Zhen Chen , Wenting Duan

Magnetic resonance (MR) protocols rely on several sequences to assess pathology and organ status properly. Despite advances in image analysis, we tend to treat each sequence, here termed modality, in isolation. Taking advantage of the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-11 Agisilaos Chartsias , Giorgos Papanastasiou , Chengjia Wang , Scott Semple , David E. Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Brain tumor imaging has been part of the clinical routine for many years to perform non-invasive detection and grading of tumors. Tumor segmentation is a crucial step for managing primary brain tumors because it allows a volumetric analysis…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Masoomeh Rahimpour , Ahmed Radwan , Henri Vandermeulen , Stefan Sunaert , Karolien Goffin , Michel Koole

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is clinically relevant in diagnoses, prognoses and surgery treatment, which requires multiple modalities to provide complementary morphological and physiopathologic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Yixin Wang , Yang Zhang , Yang Liu , Zihao Lin , Jiang Tian , Cheng Zhong , Zhongchao Shi , Jianping Fan , Zhiqiang He

Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Qianying Liu , Xiao Gu , Paul Henderson , Fani Deligianni

Semantic segmentation of brain tumours is a fundamental task in medical image analysis that can help clinicians in diagnosing the patient and tracking the progression of any malignant entities. Accurate segmentation of brain lesions is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Aditya Kasliwal , Sankarshanaa Sagaram , Laven Srivastava , Pratinav Seth , Adil Khan

Medical image segmentation of tumors and organs at risk is a time-consuming yet critical process in the clinic that utilizes multi-modality imaging (e.g, different acquisitions, data types, and sequences) to increase segmentation precision.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 Qisheng He , Nicholas Summerfield , Ming Dong , Carri Glide-Hurst

Deep learning-based medical image segmentation models suffer from performance degradation when deployed to a new healthcare center. To address this issue, unsupervised domain adaptation and multi-source domain generalization methods have…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Shishuai Hu , Zehui Liao , Yong Xia

Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face…

Image and Video Processing · Electrical Eng. & Systems 2024-11-14 Runze Cheng , Zhongao Sun , Ye Zhang , Chun Li