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Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Medical Large language models achieve strong scores on standard benchmarks; however, the transfer of those results to safe and reliable performance in clinical workflows remains a challenge. This survey reframes evaluation through a…

This paper presents AutoEval, a novel benchmark for scaling Large Language Model (LLM) assessment in formal tasks with clear notions of correctness, such as truth maintenance in translation and logical reasoning. AutoEval is the first…

Artificial Intelligence · Computer Science 2025-04-15 Rushang Karia , Daniel Bramblett , Daksh Dobhal , Siddharth Srivastava

We introduce MultiMedEval, an open-source toolkit for fair and reproducible evaluation of large, medical vision-language models (VLM). MultiMedEval comprehensively assesses the models' performance on a broad array of six multi-modal tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Corentin Royer , Bjoern Menze , Anjany Sekuboyina

Large language models (LLMs) are gaining increasing interests to improve clinical efficiency for medical diagnosis, owing to their unprecedented performance in modelling natural language. Ensuring the safe and reliable clinical…

Computation and Language · Computer Science 2024-03-26 Lei Liu , Xiaoyan Yang , Fangzhou Li , Chenfei Chi , Yue Shen , Shiwei Lyu Ming Zhang , Xiaowei Ma , Xiangguo Lyu , Liya Ma , Zhiqiang Zhang , Wei Xue , Yiran Huang , Jinjie Gu

As multimodal large language models (MLLMs) gain prominence in the medical field, the need for precise evaluation methods to assess their effectiveness has become critical. While benchmarks provide a reliable means to evaluate the…

Computation and Language · Computer Science 2024-12-17 Xiechi Zhang , Shunfan Zheng , Linlin Wang , Gerard de Melo , Zhu Cao , Xiaoling Wang , Liang He

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei

With generative artificial intelligence (AI), particularly large language models (LLMs), continuing to make inroads in healthcare, it is critical to supplement traditional automated evaluations with human evaluations. Understanding and…

This paper explores the potential of using Large Language Models (LLMs) to automate the evaluation of responses in medical Question and Answer (Q\&A) systems, a crucial form of Natural Language Processing. Traditionally, human evaluation…

Computation and Language · Computer Science 2024-09-04 Jack Krolik , Herprit Mahal , Feroz Ahmad , Gaurav Trivedi , Bahador Saket

Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the…

Computation and Language · Computer Science 2024-06-06 Yuxuan Zhou , Xien Liu , Chen Ning , Ji Wu

Critical appraisal of scientific literature is an essential skill in the biomedical field. While large language models (LLMs) can offer promising support in this task, their reliability remains limited, particularly for critical reasoning…

Computation and Language · Computer Science 2026-03-05 Doria Bonzi , Alexandre Guiggi , Frédéric Béchet , Carlos Ramisch , Benoit Favre

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

The rapid development of large language model (LLM) evaluation methodologies and datasets has led to a profound challenge: integrating state-of-the-art evaluation techniques cost-effectively while ensuring reliability, reproducibility, and…

Computation and Language · Computer Science 2024-04-10 Zhuohao Yu , Chang Gao , Wenjin Yao , Yidong Wang , Zhengran Zeng , Wei Ye , Jindong Wang , Yue Zhang , Shikun Zhang

Large language models (LLMs) garner significant attention for their unprecedented performance, leading to an increasing number of researches evaluating LLMs. However, these evaluation benchmarks are limited to assessing the…

Computation and Language · Computer Science 2024-08-21 Yu Sun , Keyu Chen , Shujie Wang , Peiji Li , Qipeng Guo , Hang Yan , Xipeng Qiu , Xuanjing Huang , Dahua Lin

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

As the performance of large language models (LLMs) continues to advance, their adoption in the medical domain is increasing. However, most existing risk evaluations largely focused on general safety benchmarks. In the medical applications,…

Computation and Language · Computer Science 2026-01-12 Jean-Philippe Corbeil , Minseon Kim , Maxime Griot , Sheela Agarwal , Alessandro Sordoni , Francois Beaulieu , Paul Vozila

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

The healthcare industry is currently experiencing an unprecedented wave of cybersecurity attacks, impacting millions of individuals. With the discovery of thousands of vulnerabilities each month, there is a pressing need to drive the…

Computation and Language · Computer Science 2024-07-23 Rikhiya Ghosh , Oladimeji Farri , Hans-Martin von Stockhausen , Martin Schmitt , George Marica Vasile

Large language models (LLMs) demonstrate significant potential in advancing medical applications, yet their capabilities in addressing medical ethics challenges remain underexplored. This paper introduces MedEthicEval, a novel benchmark…

Computation and Language · Computer Science 2025-03-05 Haoan Jin , Jiacheng Shi , Hanhui Xu , Kenny Q. Zhu , Mengyue Wu

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

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