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Multimodal Large Language Models (MLLMs) show strong visual perception, yet remain limited in reasoning about space under changing viewpoints. We study this challenge as Perspective-Conditioned Spatial Reasoning (PCSR) in 360-degree…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yuangong Chen , Wai Keung Wong , Jiaxing Li , Ioannis Patras , Xu Zheng

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu

The reasoning segmentation task, which demands a nuanced comprehension of intricate queries to accurately pinpoint object regions, is attracting increasing attention. However, Multi-modal Large Language Models (MLLM) often find it difficult…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaoyi Bao , Siyang Sun , Shuailei Ma , Kecheng Zheng , Yuxin Guo , Guosheng Zhao , Yun Zheng , Xingang Wang

A major focus of clinical imaging workflow is disease diagnosis and management, leading to medical imaging datasets strongly tied to specific clinical objectives. This scenario has led to the prevailing practice of developing task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Yunhe Gao , Zhuowei Li , Di Liu , Mu Zhou , Shaoting Zhang , Dimitris N. Metaxas

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Referring Medical Image Sequence Segmentation (Ref-MISS) is a novel and challenging task that aims to segment anatomical structures in medical image sequences (\emph{e.g.} endoscopy, ultrasound, CT, and MRI) based on natural language…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Runtian Yuan , Mohan Chen , Jilan Xu , Ling Zhou , Qingqiu Li , Yuejie Zhang , Rui Feng , Tao Zhang , Shang Gao

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Tianhong Zhou , Yin Xu , Yingtao Zhu , Chuxi Xiao , Haiyang Bian , Lei Wei , Xuegong Zhang

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have significantly impacted medical image segmentation, especially in retinal imaging, where precise segmentation is vital for diagnosis. Despite this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Shahrooz Faghihroohi , Kai Huang , Nassir Navab , M. Ali Nasseri

Medical language-guided segmentation, integrating textual clinical reports as auxiliary guidance to enhance image segmentation, has demonstrated significant improvements over unimodal approaches. However, its inherent reliance on paired…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Shuchang Ye , Usman Naseem , Mingyuan Meng , Jinman Kim

Free-text promptable 3D medical image segmentation offers an intuitive and clinically flexible interaction paradigm. However, current methods are highly sensitive to linguistic variability: minor changes in phrasing can cause substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Tongrui Zhang , Chenhui Wang , Yongming Li , Zhihao Chen , Xufeng Zhan , Hongming Shan

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

Open-Vocabulary Segmentation (OVS) has drawn increasing attention for its capacity to generalize segmentation beyond predefined categories. However, existing methods typically predict segmentation masks with simple forward inference,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Zongyan Han , Jiale Cao , Shuo Chen , Tong Wang , Jorma Laaksonen , Rao Muhammad Anwer

Existing methods for farmland remote sensing image (FRSI) segmentation generally follow a static segmentation paradigm, where analysis relies solely on the limited information contained within a single input patch. Consequently, their…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Haiyang Wu , Weiliang Mu , Jipeng Zhang , Zhong Dandan , Zhuofei Du , Haifeng Li , Tao Chao

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

Segment Anything Models (SAMs) like SEEM and SAM have demonstrated great potential in learning to segment anything. The core design of SAMs lies with Promptable Segmentation, which takes a handcrafted prompt as input and returns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Jiaxing Huang , Kai Jiang , Jingyi Zhang , Han Qiu , Lewei Lu , Shijian Lu , Eric Xing

Image segmentation is a central topic in image processing and computer vision and a key issue in many applications, e.g., in medical imaging, microscopy, document analysis and remote sensing. According to the human perception, image…

Numerical Analysis · Mathematics 2022-06-24 Laura Antonelli , Valentina De Simone , Daniela di Serafino