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Related papers: Foundation Models for AI-Enabled Biological Design

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MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

This paper aims at identifying emerging computational intelligence trends for the design and modeling of complex biometric-enabled infrastructure and systems. Biometric-enabled systems are evolving towards deep learning and deep inference…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Svetlana Yanushkevich , Shawn Eastwood , Kenneth Lai , Vlad Shmerko

Data-driven approaches are becoming more common as problem-solving techniques in many areas of research and industry. In most cases, machine learning models are the key component of these solutions, but a solution involves multiple such…

Artificial Intelligence · Computer Science 2019-06-20 Parisa Kordjamshidi , Dan Roth , Kristian Kersting

We present the first large-scale analysis of AI foundation model usage in science - not just citations or keywords. We find that adoption has grown rapidly, at nearly-exponential rates, with the highest uptake in Linguistics, Computer…

Digital Libraries · Computer Science 2025-12-01 Ana Trišović , Alex Fogelson , Janakan Sivaloganathan , Neil Thompson

The advent of foundation models has revolutionized the fields of natural language processing and computer vision, paving the way for their application in autonomous driving (AD). This survey presents a comprehensive review of more than 40…

Machine Learning · Computer Science 2024-09-06 Haoxiang Gao , Zhongruo Wang , Yaqian Li , Kaiwen Long , Ming Yang , Yiqing Shen

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

Biomolecular interactions underpin almost all biological processes, and their rational design is central to programming new biological functions. Generative AI models have emerged as powerful tools for molecular design, yet most remain…

Foundation models have gained growing interest in the IoT domain due to their reduced reliance on labeled data and strong generalizability across tasks, which address key limitations of traditional machine learning approaches. However, most…

Machine Learning · Computer Science 2025-10-10 Hui Wei , Dong Yoon Lee , Shubham Rohal , Zhizhang Hu , Ryan Rossi , Shiwei Fang , Shijia Pan

Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…

Machine Learning · Computer Science 2025-07-22 Xinliang Zhou , Chenyu Liu , Zhisheng Chen , Kun Wang , Yi Ding , Ziyu Jia , Qingsong Wen

In biomedical applications of machine learning, relevant information often has a rich structure that is not easily encoded as real-valued predictors. Examples of such data include DNA or RNA sequences, gene sets or pathways, gene…

Genomics · Quantitative Biology 2019-10-16 Jake Crawford , Casey S. Greene

The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…

Other Quantitative Biology · Quantitative Biology 2025-01-24 Himanshu Buckchash , Gyanendra Kumar Verma , Dilip K. Prasad

Advances in machine learning over the past decade have resulted in a proliferation of algorithmic applications for encoding, characterizing, and acting on complex data that may contain many high dimensional features. Recently, the emergence…

Reasoning, a crucial ability for complex problem-solving, plays a pivotal role in various real-world settings such as negotiation, medical diagnosis, and criminal investigation. It serves as a fundamental methodology in the field of…

Over the past decade, advances in generative modeling, such as generative adversarial networks, masked autoencoders, and diffusion models, have significantly transformed biological research and discovery, enabling breakthroughs in molecule…

Machine Learning · Computer Science 2026-03-10 Zihao Li , Zhichen Zeng , Xiao Lin , Feihao Fang , Yanru Qu , Zhe Xu , Zhining Liu , Xuying Ning , Tianxin Wei , Ge Liu , Hanghang Tong , Jingrui He

Artificial intelligence and machine learning are reshaping how we approach scientific discovery, not by replacing established methods but by extending what researchers can probe, predict, and design. In this roadmap we provide a…

Artificial intelligence is humanity's most promising technology because of the remarkable capabilities offered by foundation models. Yet, the same technology brings confusion and consternation: foundation models are poorly understood and…

Artificial Intelligence · Computer Science 2025-07-01 Rishi Bommasani

Generative pretraining (the "GPT" in ChatGPT) enables language models to learn from vast amounts of internet text without human supervision. This approach has driven breakthroughs across AI by allowing deep neural networks to learn from…

Neurons and Cognition · Quantitative Biology 2025-09-23 Thomas Serre , Ellie Pavlick

Advancements in artificial intelligence (AI) have transformed many scientific fields, with microbiology and microbiome research now experiencing significant breakthroughs through machine learning applications. This review provides a…

Quantitative Methods · Quantitative Biology 2025-12-19 Xu-Wen Wang , Tong Wang , Yang-Yu Liu

Continual learning--the ability to acquire, retain, and refine knowledge over time--has always been fundamental to intelligence, both human and artificial. Historically, different AI paradigms have acknowledged this need, albeit with…

Machine Learning · Computer Science 2025-06-05 Jack Bell , Luigi Quarantiello , Eric Nuertey Coleman , Lanpei Li , Malio Li , Mauro Madeddu , Elia Piccoli , Vincenzo Lomonaco
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