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Related papers: Foundation Models for AI-Enabled Biological Design

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Machine learning methods are increasingly employed to address challenges faced by biologists. One area that will greatly benefit from this cross-pollination is the problem of biological sequence design, which has massive potential for…

Quantitative Methods · Quantitative Biology 2020-10-26 Sam Sinai , Eric D Kelsic

Artificial intelligence (AI), propelled by advancements in machine learning, has made significant strides in solving complex tasks. However, the current neural network-based paradigm, while effective, is heavily constrained by inherent…

Artificial Intelligence · Computer Science 2025-06-17 Zeki Doruk Erden , Boi Faltings

The rapid integration of Artificial Intelligence (AI) into organizational technology frameworks has transformed how organizations engage with AI-driven models, influencing both operational performance and strategic innovation. With the…

Software Engineering · Computer Science 2025-10-22 Johannes Schneider , Rene Abraham

This review explores the potential of foundation models to advance laboratory automation in the materials and chemical sciences. It emphasizes the dual roles of these models: cognitive functions for experimental planning and data analysis,…

The capabilities of AI for biomedicine span a wide spectrum, from the atomic level, where it solves partial differential equations for quantum systems, to the molecular level, predicting chemical or protein structures, and further extending…

Computation and Language · Computer Science 2024-03-26 Zhenyu Bi , Sajib Acharjee Dip , Daniel Hajialigol , Sindhura Kommu , Hanwen Liu , Meng Lu , Xuan Wang

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Modeling environmental ecosystems is essential for effective resource management, sustainable development, and understanding complex ecological processes. However, traditional methods frequently struggle with the inherent complexity,…

Machine Learning · Computer Science 2025-03-06 Runlong Yu , Shengyu Chen , Yiqun Xie , Xiaowei Jia

Deep generative models that learn from the distribution of natural protein sequences and structures may enable the design of new proteins with valuable functions. While the majority of today's models focus on generating either sequences or…

Biomolecules · Quantitative Biology 2024-10-03 Chentong Wang , Sarah Alamdari , Carles Domingo-Enrich , Ava Amini , Kevin K. Yang

Artificial intelligence (AI)-driven electronic design automation (EDA) techniques have been extensively explored for VLSI circuit design applications. Most recently, foundation AI models for circuits have emerged as a new technology trend.…

Hardware Architecture · Computer Science 2025-04-08 Wenji Fang , Jing Wang , Yao Lu , Shang Liu , Yuchao Wu , Yuzhe Ma , Zhiyao Xie

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

The application of deep learning methods, particularly foundation models, in biological research has surged in recent years. These models can be text-based or trained on underlying biological data, especially omics data of various types.…

Artificial Intelligence · Computer Science 2024-12-06 Yoav Kan-Tor , Michael Morris Danziger , Eden Zohar , Matan Ninio , Yishai Shimoni

The field of deep generative modeling has grown rapidly in the last few years. With the availability of massive amounts of training data coupled with advances in scalable unsupervised learning paradigms, recent large-scale generative models…

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

The latest advancements in machine learning, specifically in foundation models, are revolutionizing the frontiers of existing software engineering (SE) processes. This is a bi-directional phenomona, where 1) software systems are now…

Software Engineering · Computer Science 2024-06-27 Luís Cruz , Xavier Franch Gutierrez , Silverio Martínez-Fernández

Foundational Models (FMs) are gaining increasing attention in the biomedical AI ecosystem due to their ability to represent and contextualize multimodal biomedical data. These capabilities make FMs a valuable tool for a variety of tasks,…

Generative artificial intelligence (GenAI) has become a transformative approach in bioinformatics that often enables advancements in genomics, proteomics, transcriptomics, structural biology, and drug discovery. To systematically identify…

Foundation models are at the forefront of AI research, appealing for their ability to learn from vast datasets and cater to diverse tasks. Yet, their significant computational demands raise issues of environmental impact and the risk of…

Machine Learning · Computer Science 2025-07-03 Leyang Xue , Meghana Madhyastha , Randal Burns , Myungjin Lee , Mahesh K. Marina