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Related papers: MOSAIK: Multi-Origin Spatial Transcriptomics Analy…

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Spatial transcriptomics (ST) is an emerging technology that enables medical computer vision scientists to automatically interpret the molecular profiles underlying morphological features. Currently, however, most deep learning-based ST…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Junchao Zhu , Ruining Deng , Tianyuan Yao , Juming Xiong , Chongyu Qu , Junlin Guo , Siqi Lu , Mengmeng Yin , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…

Genomics · Quantitative Biology 2025-12-15 Hiren Madhu , João Felipe Rocha , Tinglin Huang , Siddharth Viswanath , Smita Krishnaswamy , Rex Ying

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Siqi Lu , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yalin Zheng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Radiology reports contain rich clinical information that can be used to train imaging models without relying on costly manual annotation. However, existing approaches face critical limitations: rule-based methods struggle with linguistic…

Spatial transcriptomics (ST) has advanced significantly in the last few years. Such advancement comes with the urgent need for novel computational methods to handle the unique challenges of ST data analysis. Many artificial intelligence…

Machine Learning · Computer Science 2022-03-21 Yijun Li , Stefan Stanojevic , Lana X. Garmire

Spatial Transcriptomics (ST) reveals the spatial distribution of gene expression in tissues, offering critical insights into biological processes and disease mechanisms. However, the high cost, limited coverage, and technical complexity of…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Yi Niu , Jiashuai Liu , Yingkang Zhan , Jiangbo Shi , Di Zhang , Marika Reinius , Ines Machado , Mireia Crispin-Ortuzar , Jialun Wu , Chen Li , Zeyu Gao

We present a next-generation neural network architecture, MOSAIC, for efficient and accurate semantic image segmentation on mobile devices. MOSAIC is designed using commonly supported neural operations by diverse mobile hardware platforms…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Weijun Wang , Andrew Howard

With the rapid advancement of Spatial Resolved Transcriptomics (SRT) technology, it is now possible to comprehensively measure gene transcription while preserving the spatial context of tissues. Spatial domain identification and gene…

Genomics · Quantitative Biology 2024-08-14 Donghai Fang , Fangfang Zhu , Dongting Xie , Wenwen Min

Compressive sensing (CS) reconstructs images from sub-Nyquist measurements by solving a sparsity-regularized inverse problem. Traditional CS solvers use iterative optimizers with hand crafted sparsifiers, while early data-driven methods…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Pamuditha Somarathne , Tharindu Wickremasinghe , Amashi Niwarthana , A. Thieshanthan , Chamira U. S. Edussooriya , Dushan N. Wadduwage

Multiplexed immunofluorescence microscopy captures detailed measurements of spatially resolved, multiple biomarkers simultaneously, revealing tissue composition and cellular interactions in situ among single cells. The growing scale and…

Software Engineering · Computer Science 2025-06-03 Fang Liu , Rui He , Andrei Bombin , Ahmad B. Abdallah , Omar Eldaghar , Tommy R. Sheeley , Sam E. Ying , George Zaki

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

We present an approach to denoising spatial transcriptomics images that is particularly effective for uncovering cell identities in the regime of ultra-low sequencing depths, and also allows for interpolation of gene expression. The method…

The integration of AI in digital pathology, particularly in whole slide image (WSI) and spatial transcriptomics (ST) analysis, holds immense potential for enhancing our understanding of diseases. Despite challenges such as training pattern…

Quantitative Methods · Quantitative Biology 2024-11-18 Chao-Hui Huang , Sara Lichtarge , Diane Fernandez

Spatial transcriptomics reveals gene expression patterns within tissue context, enabling precision oncology applications such as treatment response prediction, but its high cost and technical complexity limit clinical adoption. Predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Won June Cho , Hongjun Yoon , Daeky Jeong , Hyeongyeol Lim , Yosep Chong

Efficient and accurate multi-organ segmentation from abdominal CT volumes is a fundamental challenge in medical image analysis. Existing 3D segmentation approaches are computationally and memory intensive, often processing entire volumes…

Image and Video Processing · Electrical Eng. & Systems 2025-05-19 Hania Ghouse , Muzammil Behzad

Sustaining high fidelity and high throughput of perception tasks over vision sensor streams on edge devices remains a formidable challenge, especially given the continuing increase in image sizes (e.g., generated by 4K cameras) and…

Multimedia · Computer Science 2023-05-08 Ila Gokarn , Hemanth Sabella , Yigong Hu , Tarek Abdelzaher , Archan Misra

Codon usage bias has a crucial impact on the translation efficiency and co-translational folding of proteins, necessitating the algorithmic development of codon optimization/harmonization methods, particularly for heterologous recombinant…

Vision Transformer models have shown impressive effectiveness in the surgical video understanding tasks through long-range dependency modeling. However, current methods suffer from prohibitive computational costs due to processing massive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xixi Jiang , Chen Yang , Dong Zhang , Pingcheng Dong , Xin Yang , Kwang-Ting Cheng

The rapid growth of digital pathology and advances in self-supervised deep learning have enabled the development of foundational models for various pathology tasks across diverse diseases. While multimodal approaches integrating diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Kimberly Flores , Anthony Sisk , William Speier , Corey W. Arnold

The powerful combination of the cutting-edge multi-object spectrograph MOSAIC with the world largest telescope, the ELT, will allow us to probe deeper into the Universe than was possible. MOSAIC is an extremely efficient instrument in…