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Epidemiologic and genetic studies in chronic obstructive pulmonary disease (COPD) and many complex diseases suggest subgroup disparities (e.g., by sex). We consider this problem from the standpoint of integrative analysis where we combine…

Methodology · Statistics 2023-09-26 J. Butts , C. Wendt , R. Bowler , C. P. Hersh , Q. Long , L. Eberly , S. E. Safo

When analyzing real-world data it is common to work with event ensembles, which comprise sets of observations that collectively constrain the parameters of an underlying model of interest. Such models often have a hierarchical structure,…

Machine Learning · Statistics 2024-02-22 Lukas Heinrich , Siddharth Mishra-Sharma , Chris Pollard , Philipp Windischhofer

We consider the problem of aggregating predictions or measurements from a set of human forecasters, models, sensors or other instruments which may be subject to bias or miscalibration and random heteroscedastic noise. We propose a Bayesian…

Statistical Finance · Quantitative Finance 2021-01-12 Chirag Nagpal , Robert E. Tillman , Prashant Reddy , Manuela Veloso

We study Bayesian inference methods for solving linear inverse problems, focusing on hierarchical formulations where the prior or the likelihood function depend on unspecified hyperparameters. In practice, these hyperparameters are often…

Numerical Analysis · Mathematics 2018-08-01 Qingping Zhou , Wenqing Liu , Jinglai Li , Youssef M. Marzouk

In this paper, we propose a probabilistic model for computing an interpolative decomposition (ID) in which each column of the observed matrix has its own priority or importance, so that the end result of the decomposition finds a set of…

Machine Learning · Computer Science 2022-09-30 Jun Lu , Joerg Osterrieder

Conformal prediction has emerged as a widely used framework for constructing valid prediction sets in classification and regression tasks. In this work, we extend the split conformal prediction framework to hierarchical classification,…

Machine Learning · Statistics 2026-04-13 Thomas Mortier , Alireza Javanmardi , Yusuf Sale , Eyke Hüllermeier , Willem Waegeman

The reconstruction of time-dependent Robin coefficients is a challenging inverse heat transfer problem due to its inherent ill-posedness. This paper introduces a hierarchical Bayesian approach integrated with a persistent homology (PH)…

Computation · Statistics 2026-04-27 Xiaomei Yang , Jiaying Jia , Zhiliang Deng

As modern complex neural networks keep breaking records and solving harder problems, their predictions also become less and less intelligible. The current lack of interpretability often undermines the deployment of accurate machine learning…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jacopo Teneggi , Alexandre Luster , Jeremias Sulam

This paper proposes a Heaviside composite optimization approach and presents a progressive (mixed) integer programming (PIP) method for solving multi-class classification and multi-action treatment problems with constraints. A Heaviside…

Optimization and Control · Mathematics 2024-01-08 Yue Fang , Junyi Liu , Jong-Shi Pang

Research in oncology has changed the focus from histological properties of tumors in a specific organ to a specific genomic aberration potentially shared by multiple cancer types. This motivates the basket trial, which assesses the efficacy…

Applications · Statistics 2020-02-11 Jin Jin , Marie-Karelle Riviere , Xiaodong Luo , Yingwen Dong

Various AI models are increasingly being considered as part of clinical decision-support tools. However, the trustworthiness of such models is rarely considered. Clinicians are more likely to use a model if they can understand and trust its…

Artificial Intelligence · Computer Science 2020-03-09 Evangelia Kyrimi , Somayyeh Mossadegh , Nigel Tai , William Marsh

Conformal prediction has emerged as a cutting-edge methodology in statistics and machine learning, providing prediction intervals with finite-sample frequentist coverage guarantees. Yet, its interplay with Bayesian statistics, often…

Methodology · Statistics 2026-03-27 Nina Deliu , Brunero Liseo

We present an extensible software framework, hIPPYlib, for solution of large-scale deterministic and Bayesian inverse problems governed by partial differential equations (PDEs) with infinite-dimensional parameter fields (which are…

Numerical Analysis · Mathematics 2020-09-01 Umberto Villa , Noemi Petra , Omar Ghattas

We introduce a unified framework for contextual and causal Bayesian optimisation, which aims to design intervention policies maximising the expectation of a target variable. Our approach leverages both observed contextual information and…

Machine Learning · Computer Science 2026-02-04 Vahan Arsenyan , Antoine Grosnit , Haitham Bou-Ammar , Arnak Dalalyan

Model selection in machine learning (ML) is a crucial part of the Bayesian learning procedure. Model choice may impose strong biases on the resulting predictions, which can hinder the performance of methods such as Bayesian neural networks…

Machine Learning · Statistics 2022-08-09 Simón Rodríguez Santana , Luis A. Ortega , Daniel Hernández-Lobato , Bryan Zaldívar

We extend the Bayesian Information Criterion (BIC), an asymptotic approximation for the marginal likelihood, to Bayesian networks with hidden variables. This approximation can be used to select models given large samples of data. The…

Machine Learning · Computer Science 2015-05-19 Dan Geiger , David Heckerman , Christopher Meek

We introduce a scalable Bayesian preference learning method for identifying convincing arguments in the absence of gold-standard rat- ings or rankings. In contrast to previous work, we avoid the need for separate methods to perform quality…

Computation and Language · Computer Science 2018-06-08 Edwin Simpson , Iryna Gurevych

Hierarchies feature prominently in anatomical accounts of cortical organisation. An open question is which computational (algorithmic) processes are implemented by these hierarchies. One renowned hypothesis is that cortical hierarchies…

Neurons and Cognition · Quantitative Biology 2017-09-08 Andreea O. Diaconescu , Vladimir Litvak , Christoph Mathys , Lars Kasper , Karl J. Friston , Klaas E. Stephan

Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…

Machine Learning · Statistics 2025-11-18 Debashis Chatterjee

The past decades have seen enormous improvements in computational inference based on statistical models, with continual enhancement in a wide range of computational tools, in competition. In Bayesian inference, first and foremost, MCMC…

Computation · Statistics 2015-05-12 Peter J. Green , Krzysztof Łatuszyński , Marcelo Pereyra , Christian P. Robert
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