English
Related papers

Related papers: VitaGraph: Building a Knowledge Graph for Biologic…

200 papers

Processing large complex networks recently attracted considerable interest. Complex graphs are useful in a wide range of applications from technological networks to biological systems like the human brain. Sometimes these networks are…

Data Structures and Algorithms · Computer Science 2019-12-03 Christian Schulz

There is enormous growth in various fields of research. This development is accompanied by new problems. To solve these problems efficiently and in an optimized manner, algorithms are created and described by researchers in the scientific…

Artificial Intelligence · Computer Science 2022-05-27 Jyotima Patel , Biswanath Dutta

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

Artificial Intelligence · Computer Science 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

To combat COVID-19, both clinicians and scientists need to digest vast amounts of relevant biomedical knowledge in scientific literature to understand the disease mechanism and related biological functions. We have developed a novel and…

While deep learning has revolutionized the prediction of rigid protein structures, modelling the conformational ensembles of Intrinsically Disordered Proteins (IDPs) remains a key frontier. Current AI paradigms present a trade-off: Protein…

Biomolecules · Quantitative Biology 2025-12-19 Eoin Quinn , Marco Carobene , Jean Quentin , Sebastien Boyer , Miguel Arbesú , Oliver Bent

Exploring the effects a chemical compound has on a species takes a considerable experimental effort. Appropriate methods for estimating and suggesting new effects can dramatically reduce the work needed to be done by a laboratory. In this…

Artificial Intelligence · Computer Science 2019-11-12 Erik Bryhn Myklebust , Ernesto Jimenez-Ruiz , Jiaoyan Chen , Raoul Wolf , Knut Erik Tollefsen

Biological neural networks define the brain function and intelligence of humans and other mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is closely interconnected with the spatial organization of the…

Interdisciplinary PhD programs can be challenging as the vital information needed by students may not be readily available, it is scattered across university's websites, while tacit knowledge can be obtained only by interacting with people.…

Human-Computer Interaction · Computer Science 2024-06-21 Stanislava Gardasevic , Manika Lamba

In today's data-driven world, the ability to extract meaningful information from data is becoming essential for businesses, organizations and researchers alike. For that purpose, a wide range of tools and systems exist addressing…

Machine Learning · Computer Science 2026-03-24 Gerard Pons , Besim Bilalli , Anna Queralt

The rash development of knowledge graph research has brought big driving force to its application in many areas, including the medicine and healthcare domain. However, we have found that the application of some major information processing…

Artificial Intelligence · Computer Science 2026-01-23 Chuanqing Wang , Zhenmin Zhao , Shanshan Du , Chaoqun Fei , Songmao Zhang , Ruqian Lu

Knowledge Graphs (KGs) serving as semantic networks, prove highly effective in managing complex interconnected data in different domains, by offering a unified, contextualized, and structured representation with flexibility that allows for…

Computation and Language · Computer Science 2024-10-01 Azmine Toushik Wasi

Genes are fundamental for analyzing biological systems and many recent works proposed to utilize gene expression for various biological tasks by deep learning models. Despite their promising performance, it is hard for deep neural networks…

Machine Learning · Computer Science 2023-04-12 Xinnan Dai , Caihua Shan , Jie Zheng , Xiaoxiao Li , Dongsheng Li

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Drug discovery (DD) has tremendously contributed to maintaining and improving public health. Hypothesizing that inhibiting protein misfolding can slow disease progression, researchers focus on target identification (Target ID) to find…

Quantitative Methods · Quantitative Biology 2025-01-29 Ziwen Li , Xiang 'Anthony' Chen , Youngseung Jeon

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Knowledge graphs (KGs) are widely used for representing and organizing structured knowledge in diverse domains. However, the creation and upkeep of KGs pose substantial challenges. Developing a KG demands extensive expertise in data…

Information Retrieval · Computer Science 2023-09-19 Samira Babalou , Sheeba Samuel , Birgitta König-Ries

Background : Knowledge is evolving over time, often as a result of new discoveries or changes in the adopted methods of reasoning. Also, new facts or evidence may become available, leading to new understandings of complex phenomena. This is…

Computation and Language · Computer Science 2023-04-24 Ayoub Harnoune , Maryem Rhanoui , Mounia Mikram , Siham Yousfi , Zineb Elkaimbillah , Bouchra El Asri

One of the significant barriers to the training of statistical models on knowledge graphs is the difficulty that scientists have in finding the best input data to address their prediction goal. In addition to this, a key challenge is to…

Artificial Intelligence · Computer Science 2023-11-22 Mattia Fumagalli , Marco Boffo , Daqian Shi , Mayukh Bagchi , Fausto Giunchiglia

Relation Classification (RC) in biomedical texts is essential for constructing knowledge graphs and enabling applications such as drug repurposing and clinical decision-making. We propose an error-aware teacher--student framework that…

Computation and Language · Computer Science 2025-07-22 Sinchani Chakraborty , Sudeshna Sarkar , Pawan Goyal

Large Language Models~(LLMs) have demonstrated capabilities across various applications but face challenges such as hallucination, limited reasoning abilities, and factual inconsistencies, especially when tackling complex, domain-specific…