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Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated significant success in variant effect prediction. However, their adversarial robustness remains largely unexplored. To address this gap, we…

Cryptography and Security · Computer Science 2025-12-04 Huixin Zhan , Clovis Barbour , Jason H. Moore

The Genomic Foundation Model (GFM) paradigm is expected to facilitate the extraction of generalizable representations from massive genomic data, thereby enabling their application across a spectrum of downstream applications. Despite…

Genomics · Quantitative Biology 2024-06-06 Zicheng Liu , Jiahui Li , Siyuan Li , Zelin Zang , Cheng Tan , Yufei Huang , Yajing Bai , Stan Z. Li

The generation of feasible adversarial examples is necessary for properly assessing models that work in constrained feature space. However, it remains a challenging task to enforce constraints into attacks that were designed for computer…

Artificial Intelligence · Computer Science 2022-05-04 Thibault Simonetto , Salijona Dyrmishi , Salah Ghamizi , Maxime Cordy , Yves Le Traon

Object detection models are critical components of automated systems, such as autonomous vehicles and perception-based robots, but their sensitivity to adversarial attacks poses a serious security risk. Progress in defending these models…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Alexis Winter , Jean-Vincent Martini , Romaric Audigier , Angelique Loesch , Bertrand Luvison

Adversarial learning and the robustness of Graph Neural Networks (GNNs) are topics of widespread interest in the machine learning community, as documented by the number of adversarial attacks and defenses designed for these purposes. While…

Machine Learning · Computer Science 2026-05-08 Tran Gia Bao Ngo , Zulfikar Alom , Federico Errica , Murat Kantarcioglu , Cuneyt Gurcan Akcora

Adversarial attacks on Face Recognition (FR) systems have demonstrated significant effectiveness against standalone FR models. However, their practicality diminishes in complete FR systems that incorporate Face Anti-Spoofing (FAS) models,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Fengfan Zhou , Qianyu Zhou , Hefei Ling , Xuequan Lu

Deep neural networks (DNNs) have achieved remarkable performance across a wide range of applications, while they are vulnerable to adversarial examples, which motivates the evaluation and benchmark of model robustness. However, current…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Jun Guo , Wei Bao , Jiakai Wang , Yuqing Ma , Xinghai Gao , Gang Xiao , Aishan Liu , Jian Dong , Xianglong Liu , Wenjun Wu

Machine learning-based cybersecurity systems are highly vulnerable to adversarial attacks, while Generative Adversarial Networks (GANs) act as both powerful attack enablers and promising defenses. This survey systematically reviews…

Cryptography and Security · Computer Science 2025-10-01 Tharcisse Ndayipfukamiye , Jianguo Ding , Doreen Sebastian Sarwatt , Adamu Gaston Philipo , Huansheng Ning

The field of defense strategies against adversarial attacks has significantly grown over the last years, but progress is hampered as the evaluation of adversarial defenses is often insufficient and thus gives a wrong impression of…

Machine Learning · Computer Science 2020-08-06 Francesco Croce , Matthias Hein

Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated remarkable success in variant effect prediction. However, their security and robustness under adversarial manipulation remain largely unexplored.…

Cryptography and Security · Computer Science 2025-12-22 Huixin Zhan

Adversarial attacks on graphs have posed a major threat to the robustness of graph machine learning (GML) models. Naturally, there is an ever-escalating arms race between attackers and defenders. However, the strategies behind both sides…

Machine Learning · Computer Science 2021-11-09 Qinkai Zheng , Xu Zou , Yuxiao Dong , Yukuo Cen , Da Yin , Jiarong Xu , Yang Yang , Jie Tang

Face recognition (FR) has recently made substantial progress and achieved high accuracy on standard benchmarks. However, it has raised security concerns in enormous FR applications because deep CNNs are unusually vulnerable to adversarial…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xiao Yang , Dingcheng Yang , Yinpeng Dong , Hang Su , Wenjian Yu , Jun Zhu

Adversarial examples are typically optimized with gradient-based attacks. While novel attacks are continuously proposed, each is shown to outperform its predecessors using different experimental setups, hyperparameter settings, and number…

As the number and complexity of malware attacks continue to increase, there is an urgent need for effective malware detection systems. While deep learning models are effective at detecting malware, they are vulnerable to adversarial…

Cryptography and Security · Computer Science 2023-12-18 Mahesh Datta Sai Ponnuru , Likhitha Amasala , Tanu Sree Bhimavarapu , Guna Chaitanya Garikipati

Adversarial attacks on deep-learning models pose a serious threat to their reliability and security. Existing defense mechanisms are narrow addressing a specific type of attack or being vulnerable to sophisticated attacks. We propose a new…

Machine Learning · Computer Science 2023-06-22 Mouna Rabhi , Roberto Di Pietro

Graph Foundation Models (GFMs) are pre-trained on diverse source domains and adapted to unseen targets, enabling broad generalization for graph machine learning. Despite that GFMs have attracted considerable attention recently, their…

Cryptography and Security · Computer Science 2025-11-25 Jiayi Luo , Qingyun Sun , Lingjuan Lyu , Ziwei Zhang , Haonan Yuan , Xingcheng Fu , Jianxin Li

While deep neural networks have achieved remarkable success in various computer vision tasks, they often fail to generalize to new domains and subtle variations of input images. Several defenses have been proposed to improve the robustness…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Omid Poursaeed , Tianxing Jiang , Harry Yang , Serge Belongie , SerNam Lim

Adversarial examples pose many security threats to convolutional neural networks (CNNs). Most defense algorithms prevent these threats by finding differences between the original images and adversarial examples. However, the found…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Li Chen , Qi Li , Weiye Chen , Zeyu Wang , Haifeng Li

Deep neural networks have been known to be vulnerable to adversarial examples, which are inputs that are modified slightly to fool the network into making incorrect predictions. This has led to a significant amount of research on evaluating…

Machine Learning · Computer Science 2024-12-10 Alireza Abdollahpoorrostam , Mahed Abroshan , Seyed-Mohsen Moosavi-Dezfooli

The escalating threat of adversarial attacks on deep learning models, particularly in security-critical fields, has underscored the need for robust deep learning systems. Conventional robustness evaluations have relied on adversarial…

Cryptography and Security · Computer Science 2024-11-19 Ping Guo , Cheng Gong , Xi Lin , Zhiyuan Yang , Qingfu Zhang
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