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Large Language Models (LLMs) demonstrate strong capabilities in broad knowledge representation, yet they are inherently deficient in pixel-level perceptual understanding. Although the Segment Anything Model (SAM) represents a significant…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Hao Wang , Limeng Qiao , Zequn Jie , Zhijian Huang , Chengjian Feng , Qingfang Zheng , Lin Ma , Xiangyuan Lan , Xiaodan Liang

Recent studies suggest that Visual Language Models (VLMs) hold great potential for tasks such as automated medical diagnosis. However, processing complex three-dimensional (3D) multimodal medical images poses significant challenges -…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Wu , Hui Li , Yiyun Su

Medical image segmentation allows quantifying target structure size and shape, aiding in disease diagnosis, prognosis, surgery planning, and comprehension.Building upon recent advancements in foundation Vision-Language Models (VLMs) from…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Kanchan Poudel , Manish Dhakal , Prasiddha Bhandari , Rabin Adhikari , Safal Thapaliya , Bishesh Khanal

Semi-supervised learning (SSL) has emerged as an effective paradigm for medical image segmentation, reducing the reliance on extensive expert annotations. Meanwhile, vision-language models (VLMs) have demonstrated strong generalization and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Jiaqi Guo , Mingzhen Li , Hanyu Su , Santiago López , Lexiaozi Fan , Daniel Kim , Aggelos Katsaggelos

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Multimodal large language models (MLLMs) achieve strong performance by jointly processing inputs from multiple modalities, such as vision, audio, and language. However, building such models or extending them to new modalities often requires…

Machine Learning · Computer Science 2026-03-24 Md Kaykobad Reza , Ameya Patil , Edward Ayrapetian , M. Salman Asif

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park

Recent progress in medical vision-language models (VLMs) has achieved strong performance on image-level text-centric tasks such as report generation and visual question answering (VQA). However, achieving fine-grained visual grounding and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Yang Xing , Jiong Wu , Savas Ozdemir , Ying Zhang , Yang Yang , Wei Shao , Kuang Gong

This paper aims to address universal segmentation for image and video perception with the strong reasoning ability empowered by Visual Large Language Models (VLLMs). Despite significant progress in current unified segmentation methods,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Cong Wei , Yujie Zhong , Haoxian Tan , Yong Liu , Zheng Zhao , Jie Hu , Yujiu Yang

Vision language models (VLMs) have shown significant promise in visual grounding for images as well as videos. In medical imaging research, VLMs represent a bridge between object detection and segmentation, and report understanding and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Andrew Seohwan Yu , Mohsen Hariri , Kunio Nakamura , Mingrui Yang , Xiaojuan Li , Vipin Chaudhary

Multimodal Large Language Models (MLLMs) have demonstrated strong image-level visual understanding and reasoning, yet their pixel-level perception across both images and videos remains limited. Foundation segmentation models such as the SAM…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Hao Wang , Limeng Qiao , Chi Zhang , Lin Ma , Guanglu Wan , Xiangyuan Lan , Xiaodan Liang

We introduce SAM4MLLM, an innovative approach which integrates the Segment Anything Model (SAM) with Multi-Modal Large Language Models (MLLMs) for pixel-aware tasks. Our method enables MLLMs to learn pixel-level location information without…

Artificial Intelligence · Computer Science 2024-12-17 Yi-Chia Chen , Wei-Hua Li , Cheng Sun , Yu-Chiang Frank Wang , Chu-Song Chen

Vision-Language Models (VLMs) leverage aligned visual encoders to transform images into visual tokens, allowing them to be processed similarly to text by the backbone large language model (LLM). This unified input paradigm enables VLMs to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Bangzheng Li , Fei Wang , Wenxuan Zhou , Nan Xu , Ben Zhou , Sheng Zhang , Hoifung Poon , Muhao Chen

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

Surgical scene understanding is a cornerstone of computer-assisted intervention. While recent advances, particularly in surgical image segmentation, have driven progress, real-world clinical applications require a more holistic…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jincai Huang , Shihao Zou , Yuchen Guo , Jingjing Li , Wei Ji , Kai Wang , Shanshan Wang , Weixin Si

Accurate and generalizable object segmentation in ultrasound imaging remains a significant challenge due to anatomical variability, diverse imaging protocols, and limited annotated data. In this study, we propose a prompt-driven…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Hamza Rasaee , Taha Koleilat , Hassan Rivaz

Recent advancements in foundation models have shown significant potential in medical image analysis. However, there is still a gap in models specifically designed for medical image localization. To address this, we introduce MedLAM, a 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Wenhui Lei , Xu Wei , Xiaofan Zhang , Kang Li , Shaoting Zhang
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