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Phase-separated biomolecular condensates containing proteins and RNAs can assemble into higher-order structures by forming thermodynamically stable interfaces between immiscible phases. Using a minimal model of a protein/RNA interaction…

Soft Condensed Matter · Physics 2024-07-31 Tianhao Li , William M. Jacobs

The self-assembly of binary nanoparticle superlattices from colloidal mixtures is a promising method for the fabrication of complex colloidal co-crystal structures. However, binary mixtures often form amorphous or metastable phases instead…

Soft Condensed Matter · Physics 2022-05-11 R. Allen LaCour , Timothy C. Moore , Sharon C. Glotzer

Recent developments in the synthesis of colloidal particles allow for control over shape and inter-particle interaction. One example, among others, is the so-called "Mickey Mouse" (MM) particle for which the self-assembly properties have…

Soft Condensed Matter · Physics 2015-09-16 Guido Avvisati , Marjolein Dijkstra

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

Soft Condensed Matter · Physics 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

We show that spontaneous density segregation in dense systems of aligning circle swimmers is a condensation phenomenon at odds with the phase separation scenarios usually observed in two-dimensional active matter. The condensates, which…

Soft Condensed Matter · Physics 2024-12-20 Yujia Wang , Bruno Ventéjou , Hugues Chaté , Xia-qing Shi

Nanostructured materials formed via kinetically controlled self-assembly processes gather more interest nowadays. Bicontinuous emulsion gels stabilized by colloidal particles, called bijels, are attractive materials in soft-matter as they…

We use computer simulation to investigate the self-assembly of Janus-like amphiphilic peanut-shaped nanoparticles, finding phases of clusters, bilayers and micelles in accord with ideas of packing familiar from the study of molecular…

Soft Condensed Matter · Physics 2010-02-20 Stephen Whitelam , Stefan A. F. Bon

We use molecular dynamics simulations to study the evaporation of particle-laden droplets on a heated surface. The droplets are composed of a Lennard-Jones fluid containing rigid particles which are spherical sections of an atomic lattice,…

Soft Condensed Matter · Physics 2015-06-04 Weikang Chen , Joel Koplik , Ilona Kretzschmar

Living cells are characterized by the micrometric confinement of various macromolecules at high concentrations. Using droplets containing binary polymer blends as artificial cells, we previously showed that cell-sized confinement causes…

The mechanism responsible for the compaction of the genomic DNA of bacteria inside a structure called the nucleoid is a longstanding but still lively debated question. Most puzzling is the fact that the nucleoid occupies only a small…

Biological Physics · Physics 2018-09-20 Marc Joyeux

Biomembranes, which are mainly composed of neutral and charged lipids, exhibit a large variety of functional structures and dynamics. Here, we report a coarse-grained molecular dynamics (MD) simulation of the phase separation and…

Soft Condensed Matter · Physics 2016-11-07 Hiroaki Ito , Yuji Higuchi , Naofumi Shimokawa

Biological condensates are assemblies of proteins and nucleic acids that form membraneless compartments in cells and play essential roles in cellular functions. In many cases they exhibit the physical properties of liquid droplets that…

Soft Condensed Matter · Physics 2024-01-11 Ryota Takaki , Louise Jawerth , Marko Popović , Frank Jülicher

Biological tissues exhibit complex behaviors with their dynamics often resembling inert soft matter such as liquids, polymers, colloids, and liquid crystals. These analogies enable physics-based approaches for investigations of emergent…

We use a coarse-grained molecular model to study the self-assembly process of complexes of cationic and neutral lipids with DNA molecules ("lipoplexes") - a promising nonviral carrier of DNA for gene therapy. We identify the resulting…

Soft Condensed Matter · Physics 2011-05-31 Oded Farago , Niels Grønbech-Jensen

Biofilms are bacterial aggregates that grow on moist surfaces. Thin homogeneous biofilms naturally formed on the walls of conducts may serve as biosensors, providing information on the status of microsystems (MEMS) without disrupting them.…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Baldvin Einarsson , David R. Espeso

Understanding heat transfer characteristics of phase change and enhancing thermal energy transport in nanoscale are of great interest in both theoretical and practical applications. In the present study, we investigated the nanoscale…

Computational Physics · Physics 2016-04-11 Li Li , Pengfei Ji , Yuwen Zhang

Complex colloidal cluster morphologies are desirable for the fabrication of advanced materials, such as photonic crystals and meta-materials, and can be formed through evaporation-driven packing. By coupling lattice Boltzmann and discrete…

Soft Condensed Matter · Physics 2026-05-07 Junyu Yang , Abhinav Naga , Xitong Zhang , Halim Kusumaatmaja

We present a numerical simulation of a granular material using hydrodynamic equations. We show that, in the absence of external forces, such a system phase-separates into high density and low density regions. We show that this separation is…

Soft Condensed Matter · Physics 2009-11-07 Scott A. Hill , Gene F. Mazenko

At low temperatures, colloidal particles with short-range attractive and long-range repulsive interactions can form various periodic microphases in bulk.In this paper, we investigate the self-assembly behaviour of colloids with competing…

Soft Condensed Matter · Physics 2023-12-12 Ningyi Li , Junhong Li , Lijingting Qing , Shicheng Ma , Yao Li , Baohui Li

The advent of electronic computers has revolutionised the application of statistical mechanics to the liquid state. Computers have permitted, for example, the calculation of the phase diagram of water and ice and the folding of proteins.…

Statistical Mechanics · Physics 2008-09-11 Carl McBride