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Path-integral-based molecular dynamics (MD) simulations are widely used for the calculation of numerically exact quantum Boltzmann properties and approximate dynamical quantities. A nearly universal feature of MD numerical integration…

Chemical Physics · Physics 2019-09-25 Roman Korol , Nawaf Bou-Rabee , Thomas F. Miller

Variational problems that involve Wasserstein distances and more generally optimal transport (OT) theory are playing an increasingly important role in data sciences. Such problems can be used to form an examplar measure out of various…

Machine Learning · Computer Science 2018-11-15 Marco Cuturi , Gabriel Peyré

As the problem of minimizing functionals on the Wasserstein space encompasses many applications in machine learning, different optimization algorithms on $\mathbb{R}^d$ have received their counterpart analog on the Wasserstein space. We…

Optimization and Control · Mathematics 2024-11-20 Clément Bonet , Théo Uscidda , Adam David , Pierre-Cyril Aubin-Frankowski , Anna Korba

We propose a variational regularization approach based on a multiscale representation called cylindrical shearlets aimed at dynamic imaging problems, especially dynamic tomography. The intuitive idea of our approach is to integrate a…

Numerical Analysis · Mathematics 2025-08-05 Tatiana A. Bubba , Tommi Heikkilä , Demetrio Labate , Luca Ratti

Quantifying and propagating modeling uncertainties is crucial for reliability analysis, robust optimization, and other model-based algorithmic processes in engineering design and control. Now, physics-informed machine learning (PIML)…

Machine Learning · Computer Science 2025-07-14 Manaswin Oddiraju , Bharath Varma Penumatsa , Divyang Amin , Michael Piedmonte , Souma Chowdhury

Path integral-based simulation methodologies play a crucial role for the investigation of nuclear quantum effects by means of computer simulations. However, these techniques are significantly more demanding than corresponding classical…

Statistical Mechanics · Physics 2018-01-17 Karsten Kreis , Kurt Kremer , Raffaello Potestio , Mark E. Tuckerman

Analog in-memory computing (AIMC) performs computation directly within resistive crossbar arrays, offering an energy-efficient platform to scale large vision and language models. However, non-ideal analog device properties make the training…

Machine Learning · Computer Science 2026-02-26 Quan Xiao , Jindan Li , Zhaoxian Wu , Tayfun Gokmen , Tianyi Chen

Physics-informed neural networks (PINNs) provide a flexible framework for solving forward and inverse problems governed by partial differential equations (PDEs), but standard PINN training typically relies on soft penalty formulations that…

Machine Learning · Computer Science 2026-05-12 Binghang Lu , Runyu Zhang , Changhong Mou , Na Li , Guang Lin

Dynamic inverse problems are challenging to solve due to the need to identify and incorporate appropriate regularization in both space and time. Moreover, the very large scale nature of such problems in practice presents an enormous…

Numerical Analysis · Mathematics 2025-01-23 Toluwani Okunola , Mirjeta Pasha , Misha Kilmer , Melina Freitag

A novel multiscale numerical method is developed to accelerate direct simulation Monte Carlo (DSMC) simulations for polyatomic gases with internal energy. This approach applies the general synthetic iterative scheme to stochastic…

Computational Physics · Physics 2025-01-22 Liyan Luo , Tao Huang , Qi Li , Lei Wu

Quantum state tomography (QST) is typically performed from a frequentist viewpoint using maximum likelihood estimation (MLE) which seeks to find the best plausible state consistent with the data by maximizing a likelihood function /…

Quantum Physics · Physics 2022-12-22 Daniel J. Lum , Yaakov Weinstein

Dynamic circuits use real-time outcomes of mid-circuit measurements, processed by a classical controller, to adapt subsequent operations during circuit execution. This additional flexibility over static circuits comes at a price.…

Quantum Physics · Physics 2026-05-28 Innocenzo Fulginiti , Yanbin Chen , Christian B. Mendl , Helmut Seidl

This paper considers the computer model calibration problem and provides a general frequentist solution. Under the proposed framework, the data model is semi-parametric with a nonparametric discrepancy function which accounts for any…

Methodology · Statistics 2015-09-14 Raymond K. W. Wong , Curtis B. Storlie , Thomas C. M. Lee

In-memory computing (IMC) has been shown to be a promising approach for solving binary optimization problems while significantly reducing energy and latency. Building on the advantages of parallel computation, we propose an IMC-compatible…

Dynamic Contrast-enhanced Magnetic Resonance Imaging (DCE-MRI) is an important tool for detecting subtle kinetic changes in cancerous tissue. Quantitative analysis of DCE-MRI typically involves the convolution of an arterial input function…

Applications · Statistics 2020-04-22 Volker J. Schmid , Brandon Whitcher , Anwar R. Padhani , Guang-Zhong Yang

The Core Imaging Library (CIL) is an open-source versatile Python framework for solving inverse problems with special emphasis on imaging applications such as computed tomography (CT), using a plug-in architecture for data and operators,…

Deep neural networks are notorious for being sensitive to small well-chosen perturbations, and estimating the regularity of such architectures is of utmost importance for safe and robust practical applications. In this paper, we investigate…

Machine Learning · Statistics 2019-10-28 Kevin Scaman , Aladin Virmaux

Despite decades of advancements, the simulation of fluids remains one of the most challenging areas of in scientific computing. Supported by the necessity of gradient information in deep learning, differentiable simulators have emerged as…

Machine Learning · Computer Science 2025-10-21 Aleksandra Franz , Hao Wei , Luca Guastoni , Nils Thuerey

Renormalization is a powerful concept in the many-body problem. Inspired by the highly successful density matrix renormalization group (DMRG) algorithm, and the quantum chemical graphical representation of configuration space, we introduce…

Chemical Physics · Physics 2016-03-23 Zhendong Li , Garnet Kin-Lic Chan

Recent demonstrations on specialized benchmarks have reignited excitement for quantum computers, yet whether they can deliver an advantage for practical real-world problems remains an open question. Here, we show that probabilistic…