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Motivated by the interpretability question in ML models as a crucial element for the successful deployment of AI systems, this paper focuses on rule extraction as a means for neural networks interpretability. Through a systematic literature…

Machine Learning · Computer Science 2023-12-21 Sara El Mekkaoui , Loubna Benabbou , Abdelaziz Berrado

Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse folding, and biomolecular interaction modeling. However, the…

Machine Learning · Computer Science 2026-03-30 Senura Hansaja Wanasekara , Minh-Duong Nguyen , Xiaochen Liu , Nguyen H. Tran , Ken-Tye Yong

Recently, several methods have leveraged deep generative modeling to produce example-based explanations of image classifiers. Despite producing visually stunning results, these methods are largely disconnected from classical explainability…

Machine Learning · Computer Science 2025-09-11 Philipp Vaeth , Alexander M. Fruehwald , Benjamin Paassen , Magda Gregorova

In this paper, we address the critical need for interpretable and uncertainty-aware machine learning models in the context of online learning for high-risk industries, particularly cyber-security. While deep learning and other complex…

Machine Learning · Computer Science 2024-11-15 Benjamin Kolicic , Alberto Caron , Chris Hicks , Vasilios Mavroudis

Generative methods (Gen-AI) are reviewed with a particular goal of solving tasks in machine learning and Bayesian inference. Generative models require one to simulate a large training dataset and to use deep neural networks to solve a…

Computation · Statistics 2025-05-20 Maria Nareklishvili , Nick Polson , Vadim Sokolov

Mechanistic interpretability (MI) is an emerging sub-field of interpretability that seeks to understand a neural network model by reverse-engineering its internal computations. Recently, MI has garnered significant attention for…

Artificial Intelligence · Computer Science 2025-10-14 Daking Rai , Yilun Zhou , Shi Feng , Abulhair Saparov , Ziyu Yao

In this article, we first give an introduction to artificial intelligence and its applications in biology and medicine in Section 1. Deep learning methods are then described in Section 2. We narrow down the focus of the study on textual…

Artificial Intelligence · Computer Science 2022-03-08 Milad Moradi , Matthias Samwald

Although current deep models for face tasks surpass human performance on some benchmarks, we do not understand how they work. Thus, we cannot predict how it will react to novel inputs, resulting in catastrophic failures and unwanted biases…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Thrupthi Ann John , Vineeth N Balasubramanian , C. V. Jawahar

With the growing complexity and capability of large language models, a need to understand model reasoning has emerged, often motivated by an underlying goal of controlling and aligning models. While numerous interpretability and steering…

Machine Learning · Computer Science 2025-02-12 Usha Bhalla , Suraj Srinivas , Asma Ghandeharioun , Himabindu Lakkaraju

This thesis explores the generation of local explanations for already deployed machine learning models, aiming to identify optimal conditions for producing meaningful explanations considering both data and user requirements. The primary…

Artificial Intelligence · Computer Science 2024-02-19 julien Delaunay

With the continue development of Convolutional Neural Networks (CNNs), there is a growing concern regarding representations that they encode internally. Analyzing these internal representations is referred to as model interpretation. While…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Hamed Behzadi-Khormouji , José Oramas

The thesis explores the role machine learning methods play in creating intuitive computational models of neural processing. Combined with interpretability techniques, machine learning could replace human modeler and shift the focus of human…

Neurons and Cognition · Quantitative Biology 2020-10-20 Ilya Kuzovkin

The increasing complexity of AI systems has made understanding their behavior critical. Numerous interpretability methods have been developed to attribute model behavior to three key aspects: input features, training data, and internal…

Machine Learning · Computer Science 2025-05-30 Shichang Zhang , Tessa Han , Usha Bhalla , Himabindu Lakkaraju

Language models based on the Transformer architecture achieve excellent results in many language-related tasks, such as text classification or sentiment analysis. However, despite the architecture of these models being well-defined, little…

Computation and Language · Computer Science 2025-04-14 Miguel López-Otal , Jorge Gracia , Jordi Bernad , Carlos Bobed , Lucía Pitarch-Ballesteros , Emma Anglés-Herrero

Understanding the molecular processes that drive cellular life is a fundamental question in biological research. Ambitious programs have gathered a number of molecular datasets on large populations. To decipher the complex cellular…

Genomics · Quantitative Biology 2023-03-22 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Jean-Michel Arbona , Benjamin Audit , Pierre Borgnat

Deep Learning and Machine Learning based models have become extremely popular in text processing and information retrieval. However, the non-linear structures present inside the networks make these models largely inscrutable. A significant…

Information Retrieval · Computer Science 2026-03-12 Sourav Saha , Debapriyo Majumdar , Mandar Mitra

There is a growing concern about typically opaque decision-making with high-performance machine learning algorithms. Providing an explanation of the reasoning process in domain-specific terms can be crucial for adoption in risk-sensitive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Aditya Chattopadhyay , Stewart Slocum , Benjamin D. Haeffele , Rene Vidal , Donald Geman

The rapid advancement of generative models has empowered modern AI systems to comprehend and produce highly sophisticated content, even achieving human-level performance in specific domains. However, these models are fundamentally…

Despite the remarkable performance, Deep Neural Networks (DNNs) behave as black-boxes hindering user trust in Artificial Intelligence (AI) systems. Research on opening black-box DNN can be broadly categorized into post-hoc methods and…

Machine Learning · Computer Science 2021-06-25 Sandareka Wickramanayake , Wynne Hsu , Mong Li Lee

Identification of input data points relevant for the classifier (i.e. serve as the support vector) has recently spurred the interest of researchers for both interpretability as well as dataset debugging. This paper presents an in-depth…

Machine Learning · Computer Science 2020-09-30 Dominique Mercier , Shoaib Ahmed Siddiqui , Andreas Dengel , Sheraz Ahmed