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Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

Artificial intelligence methods are being increasingly applied across various domains, but their often opaque nature has raised concerns about accountability and trust. In response, the field of explainable AI (XAI) has emerged to address…

Neural and Evolutionary Computing · Computer Science 2024-10-18 Ryan Zhou , Jaume Bacardit , Alexander Brownlee , Stefano Cagnoni , Martin Fyvie , Giovanni Iacca , John McCall , Niki van Stein , David Walker , Ting Hu

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

Robustness has become one of the most critical problems in machine learning (ML). The science of interpreting ML models to understand their behavior and improve their robustness is referred to as explainable artificial intelligence (XAI).…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Patrick Koller , Amil V. Dravid , Guido M. Schuster , Aggelos K. Katsaggelos

The need for interpretable and accountable intelligent systems grows along with the prevalence of artificial intelligence applications used in everyday life. Explainable intelligent systems are designed to self-explain the reasoning behind…

Human-Computer Interaction · Computer Science 2020-08-06 Sina Mohseni , Niloofar Zarei , Eric D. Ragan

Predictive Process Monitoring (PPM) often uses deep learning models to predict the future behavior of ongoing processes, such as predicting process outcomes. While these models achieve high accuracy, their lack of interpretability…

Artificial Intelligence · Computer Science 2025-06-23 Soobin Chae , Suhwan Lee , Hanna Hauptmann , Hajo A. Reijers , Xixi Lu

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Over the last few years there has been rapid research growth into eXplainable Artificial Intelligence (XAI) and the closely aligned Interpretable Machine Learning (IML). Drivers for this growth include recent legislative changes and…

Artificial Intelligence · Computer Science 2021-07-08 Richard Dazeley , Peter Vamplew , Cameron Foale , Charlotte Young , Sunil Aryal , Francisco Cruz

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Effectively explaining decisions of black-box machine learning models is critical to responsible deployment of AI systems that rely on them. Recognizing their importance, the field of explainable AI (XAI) provides several techniques to…

Artificial Intelligence · Computer Science 2025-07-25 Yao Rong , Peizhu Qian , Vaibhav Unhelkar , Enkelejda Kasneci

Voice disorders affect a significant portion of the population, and the ability to diagnose them using automated, non-invasive techniques would represent a substantial advancement in healthcare, improving the quality of life of patients.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-25 Davide Ghia , Gabriele Ciravegna , Alkis Koudounas , Marco Fantini , Erika Crosetti , Giovanni Succo , Tania Cerquitelli

Explainable AI (XAI) methods focus on explaining what a neural network has learned - in other words, identifying the features that are the most influential to the prediction. In this paper, we call them "distinguishing features". However,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Kaili Wang , Jose Oramas , Tinne Tuytelaars

Lung cancer remains one of the most prevalent and fatal diseases worldwide, demanding accurate and timely diagnosis and treatment. Recent advancements in large AI models have significantly enhanced medical image understanding and clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Jiachen Zhong , Yiting Wang , Di Zhu , Ziwei Wang

With the advances in artificial intelligence (AI), data-driven algorithms are becoming increasingly popular in the medical domain. However, due to the nonlinear and complex behavior of many of these algorithms, decision-making by such…

Quantitative Methods · Quantitative Biology 2024-07-18 Amirehsan Ghasemi , Soheil Hashtarkhani , David L Schwartz , Arash Shaban-Nejad

The increasing complexity of machine learning models in computer vision, particularly in face verification, requires the development of explainable artificial intelligence (XAI) to enhance interpretability and transparency. This study…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Miriam Doh , Caroline Mazini Rodrigues , N. Boutry , L. Najman , Matei Mancas , Bernard Gosselin

Melanoma is one of the most aggressive and deadliest skin cancers, leading to mortality if not detected and treated in the early stages. Artificial intelligence techniques have recently been developed to help dermatologists in the early…

Machine Learning · Computer Science 2026-02-19 Wadduwage Shanika Perera , ABM Islam , Van Vung Pham , Min Kyung An

Computer Vision, and hence Artificial Intelligence-based extraction of information from images, has increasingly received attention over the last years, for instance in medical diagnostics. While the algorithms' complexity is a reason for…

Human-Computer Interaction · Computer Science 2020-07-14 Christian Meske , Enrico Bunde

Artificial intelligence now outperforms humans in several scientific and engineering tasks, yet its internal representations often remain opaque. In this Perspective, we argue that explainable artificial intelligence (XAI), combined with…

Artificial Intelligence · Computer Science 2026-02-17 Ricardo Vinuesa , Steven L. Brunton , Gianmarco Mengaldo