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Vision-language pretraining has driven significant progress in medical image analysis. However, current methods typically supervise visual encoders using one-hot labels or free-form text, neither of which effectively captures the complex…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xiyao Wang , Xiaoyu Tan , Yang Dai , Yuxuan Fu , Shuo Li , Xihe Qiu

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

Recent advances in multimodal recommendation (MMR) highlight the potential of integrating visual and textual content to enrich item representations. However, existing methods often rely on coarse visual features and naive fusion strategies,…

Information Retrieval · Computer Science 2025-11-11 Hai-Dang Kieu , Min Xu , Thanh Trung Huynh , Dung D. Le

Objectives: We aim to dynamically retrieve informative demonstrations, enhancing in-context learning in multimodal large language models (MLLMs) for disease classification. Methods: We propose a Retrieval-Augmented In-Context Learning…

Artificial Intelligence · Computer Science 2025-05-06 Zaifu Zhan , Shuang Zhou , Xiaoshan Zhou , Yongkang Xiao , Jun Wang , Jiawen Deng , He Zhu , Yu Hou , Rui Zhang

Contrastive pre-training on image-text pairs, exemplified by CLIP, becomes a standard technique for learning multi-modal visual-language representations. Although CLIP has demonstrated remarkable performance, training it from scratch on…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Jihao Liu , Jinliang Zheng , Boxiao Liu , Yu Liu , Hongsheng Li

Early-stage scoliosis is often difficult to detect, particularly in adolescents, where delayed diagnosis can lead to serious health issues. Traditional X-ray-based methods carry radiation risks and rely heavily on clinical expertise,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Haiqing Li , Yuzhi Guo , Feng Jiang , Thao M. Dang , Hehuan Ma , Qifeng Zhou , Jean Gao , Junzhou Huang

Multiple instance learning (MIL) is a promising approach for weakly supervised classification in pathology using whole slide images (WSIs). However, conventional MIL methods such as Attention-Based Deep Multiple Instance Learning (ABMIL)…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Hassan Keshvarikhojasteh , Mihail Tifrea , Sibylle Hess , Josien P. W. Pluim , Mitko Veta

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Incremental learning (IL) aims to overcome catastrophic forgetting of previous tasks while learning new ones. Existing IL methods make strong assumptions that the incoming task type will either only increases new classes or domains (i.e.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Sheng Luo , Yi Zhou , Tao Zhou

Early detection of oral cancer and potentially malignant diseases is a major challenge in low-resource settings due to the scarcity of annotated data. We provide a unified approach for four-class oral lesion classification that incorporates…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Rupam Mukherjee , Rajkumar Daniel , Soujanya Hazra , Shirin Dasgupta , Subhamoy Mandal

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

The level of tumour-infiltrating lymphocytes (TILs) is a prognostic factor for patients with (triple-negative) breast cancer (BC). Computational TIL assessment (CTA) has the potential to assist pathologists in this labour-intensive task,…

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen

Accurate disease interpretation from radiology remains challenging due to imaging heterogeneity. Achieving expert-level diagnostic decisions requires integration of subtle image features with clinical knowledge. Yet major vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Difei Gu , Yunhe Gao , Mu Zhou , Dimitris Metaxas

Clinicians make routine diagnosis by scrutinizing patients' medical signs and symptoms, a skill popularly referred to as "Clinical Eye". This skill evolves through trial-and-error and improves with time. The success of the therapeutic…

Quantitative Methods · Quantitative Biology 2021-09-16 Amit K Chattopadhyay , Subhagata Chattopadhyay

Medical image segmentation is a cornerstone of computer-assisted diagnosis and treatment planning. While recent multimodal vision-language models have shown promise in enhancing semantic understanding through textual descriptions, their…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Saivan Talaei , Fatemeh Daneshfar , Abdulhady Abas Abdullah , Mustaqeem Khan

Medical reports with substantial information can be naturally complementary to medical images for computer vision tasks, and the modality gap between vision and language can be solved by vision-language matching (VLM). However, current…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Chen Wenting , Liu Jie , Yuan Yixuan

How well are unimodal vision and language models aligned? Although prior work have approached answering this question, their assessment methods do not directly translate to how these models are used in practical vision-language tasks. In…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Le Zhang , Qian Yang , Aishwarya Agrawal

Optical coherence tomography (OCT), a commonly used retinal imaging modality, plays a central role in retinal disease diagnosis by providing high-resolution visualization of retinal layers. While deep learning (DL) has achieved expert-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tienyu Chang , Tianhao Li , Ruogu Fang , Jiang Bian , Yu Huang

Multiple instance learning (MIL) is a variation of traditional supervised learning problems where data (referred to as bags) are composed of sub-elements (referred to as instances) and only bag labels are available. MIL has a variety of…

Machine Learning · Computer Science 2018-05-02 Han Bao , Tomoya Sakai , Issei Sato , Masashi Sugiyama