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Latent reasoning enables reasoning over continuous hidden states rather than explicit tokens, avoiding the language bottleneck and inference overhead of chain-of-thought for medical VQA. However, existing methods suffer from modality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Qiaoru Li , Shaotian Liang , Jintao Chen , Haoran Sun , Yuxiang Cai , Jianwei Yin , Yankai Jiang

Wound healing is a complex process involving changes in collagen fibers. Accurate monitoring of these changes is crucial for assessing the progress of wound healing and has significant implications for guiding clinical treatment strategies…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Juan He , Xiaoyan Wang , Long Chen , Yunpeng Cai , Zhengshan Wang

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease decreasing life quality through symptoms such as bloody diarrhoea and abdominal pain. Endoscopy is a cornerstone of diagnosis and monitoring of UC. The Mayo endoscopic subscore…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Bjørn Leth Møller , Bobby Zhao Sheng Lo , Johan Burisch , Flemming Bendtsen , Ida Vind , Bulat Ibragimov , Christian Igel

We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Hyun Do Jung , Jungwon Choi , Hwiyoung Kim

Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Zhuchen Shao , Hao Bian , Yang Chen , Yifeng Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Vision-Language Models (VLMs) have achieved remarkable progress, yet their large scale often renders them impractical for resource-constrained environments. This paper introduces Unified Reinforcement and Imitation Learning (RIL), a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Byung-Kwan Lee , Ryo Hachiuma , Yong Man Ro , Yu-Chiang Frank Wang , Yueh-Hua Wu

Ulcerative colitis (UC) classification, which is an important task for endoscopic diagnosis, involves two main difficulties. First, endoscopic images with the annotation about UC (positive or negative) are usually limited. Second, they show…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Shota Harada , Ryoma Bise , Hideaki Hayashi , Kiyohito Tanaka , Seiichi Uchida

The advancement of Object Detection (OD) using Deep Learning (DL) is often hindered by the significant challenge of acquiring large, accurately labeled datasets, a process that is time-consuming and expensive. While techniques like Active…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Isac Holm

Vision In-Context Learning (VICL) enables inpainting models to quickly adapt to new visual tasks from only a few prompts. However, existing methods suffer from two key issues: (1) selecting only the most similar prompt discards…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Wenwen Liao , Jianbo Yu , Yuansong Wang , Shifu Yan , Xiaofeng Yang

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Kevin Thandiackal , Boqi Chen , Pushpak Pati , Guillaume Jaume , Drew F. K. Williamson , Maria Gabrani , Orcun Goksel

Medical image segmentation remains challenging due to the high cost of pixel-level annotations for training. In the context of weak supervision, clinician gaze data captures regions of diagnostic interest; however, its sparsity limits its…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jingkun Chen , Haoran Duan , Xiao Zhang , Boyan Gao , Vicente Grau , Jungong Han

The accurate evaluation of left atrial fibrosis via high-quality 3D Late Gadolinium Enhancement (LGE) MRI is crucial for atrial fibrillation management but is hindered by factors like patient movement and imaging variability. The pursuit of…

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

High-quality Late Gadolinium Enhancement (LGE) MRI can be helpful for atrial fibrillation management, yet scan quality is frequently compromised by patient motion, irregular breathing, and suboptimal image acquisition timing. While Multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 K M Arefeen Sultan , Kaysen Hansen , Benjamin Orkild , Alan Morris , Eugene Kholmovski , Erik Bieging , Eugene Kwan , Ravi Ranjan , Ed DiBella , Shireen Elhabian

Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative…

Machine Learning · Computer Science 2025-11-11 Ziyang Gao , Annie Cheung , Yihao Ou

When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

Endoscopic imaging is commonly used to diagnose Ulcerative Colitis (UC) and classify its severity. It has been shown that deep learning based methods are effective in automated analysis of these images and can potentially be used to aid…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Ümit Mert Çağlar , Alperen İnci , Oğuz Hanoğlu , Görkem Polat , Alptekin Temizel