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Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory. In the nervous system, the brain…

Neurons and Cognition · Quantitative Biology 2022-06-20 Thi Kim Thoa Thieu , Roderick Melnik

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

Neurons and Cognition · Quantitative Biology 2014-05-07 Pooja Chandrashekar

Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

Objective - This work introduces Dareplane, a modular and broad technology-agnostic open source software platform for brain-computer interface research with an application focus on adaptive deep brain stimulation (aDBS). One difficulty for…

Other Quantitative Biology · Quantitative Biology 2025-02-19 Matthias Dold , Joana Pereira , Bastian Sajonz , Volker A. Coenen , Jordy Thielen , Marcus L. F. Janssen , Michael Tangermann

Facial phenotyping has recently been successfully exploited for medical diagnosis as a novel way to diagnose a range of diseases, where facial biometrics has been revealed to have rich links to underlying genetic or medical causes. In this…

Artificial Intelligence · Computer Science 2021-05-18 Richard Jiang , Paul Chazot , Danny Crookes , Ahmed Bouridane , M Emre Celebi

We present a neural network approach for closed-loop deep brain stimulation (DBS). We cast the problem of finding an optimal neurostimulation strategy as a control problem. In this setting, control policies aim to optimize therapeutic…

Optimization and Control · Mathematics 2023-11-14 Malvern Madondo , Deepanshu Verma , Lars Ruthotto , Nicholas Au Yong

Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Sabrina Zhu

Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

Parkinson's disease (PD) is the most widespread movement condition and the second most common neurodegenerative disorder, following Alzheimer's. Movement symptoms and imaging techniques are the most popular ways to diagnose this disease.…

Sound · Computer Science 2024-10-28 Paria Ghaheri , Ahmadreza Shateri , Hamid Nasiri

Virtual Reality (VR) has emerged as a promising tool for enhancing social skills and emotional well-being in individuals with Autism Spectrum Disorder (ASD). Through a technical exploration, this study employs a multiplayer serious gaming…

Deep Brain Stimulation (DBS) is a well-established neurosurgical treatment aiming at symptom alleviation in a range of neurological and psychiatric diseases. Computational models of DBS are widely used to investigate the effects of…

Systems and Control · Electrical Eng. & Systems 2025-11-17 Anna Franziska Frigge , Alexander Medvedev

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

Artificial Intelligence · Computer Science 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

Parkinson's disease (PD) is a progressive neurological disorder primarily affecting motor function resulting in tremor at rest, rigidity, bradykinesia, and postural instability. The physical severity of PD impairments can be quantified…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Mandy Lu , Kathleen Poston , Adolf Pfefferbaum , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Juan Carlos Niebles , Ehsan Adeli

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Signal Processing · Electrical Eng. & Systems 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide and affects around 1% of the (60+ years old) elderly population in industrial nations. More than 80% of PD patients suffer from motor symptoms, which…

The current body of research on Parkinson's disease (PD) screening, monitoring, and management has evolved along two largely independent trajectories. The first research community focuses on multimodal sensing of PD-related biomarkers using…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Hassan Hizeh , Rim Chighri , Muhammad Mahboob Ur Rahman , Mohamed A. Bahloul , Ali Muqaibel , Tareq Y. Al-Naffouri

Parkinson's Disease (PD) is a neurodegenerative disorder that significantly impacts motor and non-motor functions. There is currently no treatment that slows or stops neurodegeneration in PD. In this context, assistive technologies (ATs)…

Human-Computer Interaction · Computer Science 2025-05-27 Subek Acharya , Sansrit Paudel

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerged as a powerful tool to enhance PD classification and diagnostic accuracy, particularly by…

Models of the cortico-basal ganglia network and volume conductor models of the brain can provide insight into the mechanisms of action of deep brain stimulation (DBS). In this study, the coupling of a network model, under parkinsonian…

Neurons and Cognition · Quantitative Biology 2017-05-31 Christian Schmidt , Eleanor Dunn , Madeleine Lowery , Ursula van Rienen