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Goal-oriented de novo molecule design, namely generating molecules with specific property or substructure constraints, is a crucial yet challenging task in drug discovery. Existing methods, such as Bayesian optimization and reinforcement…

Computational Engineering, Finance, and Science · Computer Science 2025-02-28 Chuanliu Fan , Ziqiang Cao , Zicheng Ma , Nan Yu , Yimin Peng , Jun Zhang , Yiqin Gao , Guohong Fu

The use of large language models (LLMs) for qualitative analysis is gaining attention in various fields, including software engineering, where qualitative methods are essential for understanding human and social factors. This study aimed to…

Software Engineering · Computer Science 2025-03-11 Matheus de Morais Leça , Lucas Valença , Reydne Santos , Ronnie de Souza Santos

This paper provides a primer on Large Language Models (LLMs) and identifies their strengths, limitations, applications and research directions. It is intended to be useful to those in academia and industry who are interested in gaining an…

Computation and Language · Computer Science 2024-12-09 Sandra Johnson , David Hyland-Wood

Large Language Model(LLM) inference demands massive compute and energy, making domain-specific tasks expensive and unsustainable. As foundation models keep scaling, we ask: Is bigger always better for hardware design? Our work tests this by…

This paper investigates the utilization of Large Language Models (LLMs) for solving complex linguistic puzzles, a domain requiring advanced reasoning and adept translation capabilities akin to human cognitive processes. We explore specific…

Computation and Language · Computer Science 2025-02-04 Zheng-Lin Lin , Yu-Fei Shih , Shu-Kai Hsieh

Large Language Models (LLMs) based agents are transforming the programming language landscape by facilitating learning for beginners, enabling code generation, and optimizing documentation workflows. Hardware Description Languages (HDLs),…

Hardware Architecture · Computer Science 2025-01-03 Mark Zakharov , Farzaneh Rabiei Kashanaki , Jose Renau

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

Artificial Intelligence · Computer Science 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

The integration of Large Language Models (LLMs) into Electronic Design Automation (EDA) and hardware security is rapidly reshaping the semiconductor industry. While LLMs offer unprecedented capabilities in generating Register Transfer Level…

Cryptography and Security · Computer Science 2026-05-21 Johann Knechtel , Ozgur Sinanoglu , Ramesh Karri

Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works…

Computation and Language · Computer Science 2024-10-18 Humza Naveed , Asad Ullah Khan , Shi Qiu , Muhammad Saqib , Saeed Anwar , Muhammad Usman , Naveed Akhtar , Nick Barnes , Ajmal Mian

Accurate estimation of project costs and durations remains a pivotal challenge in software engineering, directly impacting budgeting and resource management. Traditional estimation techniques, although widely utilized, often fall short due…

Software Engineering · Computer Science 2024-09-17 Justin Carpenter , Chia-Ying Wu , Nasir U. Eisty

Large Language Models (LLMs) have propelled groundbreaking advancements across several domains and are commonly used for text generation applications. However, the computational demands of these complex models pose significant challenges,…

Declarative specifications have a vital role to play in developing safe and dependable software systems. Writing specifications correctly, however, remains particularly challenging. This paper presents a controlled experiment on using large…

Software Engineering · Computer Science 2025-07-22 Yang Hong , Shan Jiang , Yulei Fu , Sarfraz Khurshid

Large language models (LLMs) have demonstrated impressive performance across a wide range of Natural Language Processing (NLP) tasks. However, ensuring their effectiveness across multiple languages presents unique challenges. Multilingual…

Computation and Language · Computer Science 2025-05-20 Shubham Vatsal , Harsh Dubey , Aditi Singh

This paper presents a comprehensive exploration of leveraging Large Language Models (LLMs), specifically GPT-4, in the field of instructional design. With a focus on scaling evidence-based instructional design expertise, our research aims…

Computation and Language · Computer Science 2023-06-27 Gautam Yadav

Spoken Language Understanding (SLU) models are a core component of voice assistants (VA), such as Alexa, Bixby, and Google Assistant. In this paper, we introduce a pipeline designed to extend SLU systems to new languages, utilizing Large…

Computation and Language · Computer Science 2024-04-04 Jakub Hoscilowicz , Pawel Pawlowski , Marcin Skorupa , Marcin Sowański , Artur Janicki

Microfluidic devices have emerged as powerful tools in various laboratory applications, but the complexity of their design limits accessibility for many practitioners. While progress has been made in microfluidic design automation (MFDA), a…

Artificial Intelligence · Computer Science 2026-02-25 Jasper Davidson , Skylar Stockham , Allen Boston , Ashton Snelgrove , Valerio Tenace , Pierre-Emmanuel Gaillardon

The planning ability of Large Language Models (LLMs) has garnered increasing attention in recent years due to their remarkable capacity for multi-step reasoning and their ability to generalize across a wide range of domains. While some…

Artificial Intelligence · Computer Science 2025-02-19 Mohamed Aghzal , Erion Plaku , Gregory J. Stein , Ziyu Yao

Performance modeling, a pivotal domain in program cost analysis, currently relies on manually crafted models constrained by various program and hardware limitations, especially in the intricate landscape of GPGPU. Meanwhile, Large Language…

Performance · Computer Science 2025-03-17 Khoi N. M. Nguyen , Hoang Duy Nguyen Do , Huyen Thao Le , Thanh Tuan Dao

The growing demand for Domain-Specific Architecture (DSA) has driven the development of Agile Hardware Development Methodology (AHDM). Hardware Construction Language (HCL) like Chisel offers high-level abstraction features, making it an…

Artificial Intelligence · Computer Science 2025-04-29 Bowei Wang , Jiaran Gao , Yelai Feng , Renzhi Chen , Shanshan Li , Lei Wang

With the rapid evolution of global autonomous driving technology, the demand for its core sensing hardware, Light Detection and Ranging (LiDAR), is escalating. As the light source part of the LiDAR system, lasers, particularly the…

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