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Decoding the linguistic intricacies of the genome is a crucial problem in biology, and pre-trained foundational models such as DNABERT and Nucleotide Transformer have made significant strides in this area. Existing works have largely hinged…

Genomics · Quantitative Biology 2024-03-20 Zhihan Zhou , Yanrong Ji , Weijian Li , Pratik Dutta , Ramana Davuluri , Han Liu

The Byte Pair Encoding algorithm can be safely batched to merge hundreds of pairs of tokens at a time when building up a tokenizer's vocabulary. This technique combined with reducing the memory footprint of text used in vocabulary training…

Computation and Language · Computer Science 2024-08-12 Alexander P. Morgan

Subword tokenization methods, such as Byte-Pair Encoding (BPE), significantly impact the performance and efficiency of large language models (LLMs). The standard approach involves training a general-purpose tokenizer that uniformly…

Computation and Language · Computer Science 2026-01-30 Vijini Liyanage , François Yvon

DNA language models have advanced genomics, but their downstream performance varies widely due to differences in tokenization, pretraining data, and architecture. We argue that a major bottleneck lies in tokenizing sparse and unevenly…

Genomics · Quantitative Biology 2025-12-23 Xiaoxiao Zhou , Zihan Wang , Jingbo Shang , Yang E. Li

Byte Pair Encoding (BPE) is a widely used tokenization algorithm, whose tokens cannot extend across pre-tokenization boundaries, functionally limiting it to representing at most full words. The BoundlessBPE and SuperBPE algorithms extend…

Computation and Language · Computer Science 2026-04-08 Craig W. Schmidt , Chris Tanner , Yuval Pinter

Byte-Pair Encoding (BPE) has become a widely adopted subword tokenization method in modern language models due to its simplicity and strong empirical performance across downstream tasks. However, applying BPE to unsegmented languages such…

Computation and Language · Computer Science 2025-06-23 Yifan Hu , Frank Liang , Dachuan Zhao , Jonathan Geuter , Varshini Reddy , Craig W. Schmidt , Chris Tanner

Currently, many studies view DNA sequences as a special type of language and utilize Transformers to model them. These studies use fixed-length k-mer segmentation and BPE subword tokenization but lack a systematic evaluation to determine…

Computation and Language · Computer Science 2025-07-22 Chenlei Gong , Yuanhe Tian , Lei Mao , Yan Song

Tokenization is the first -- and often least scrutinized -- step of most NLP pipelines. Standard algorithms for learning tokenizers rely on frequency-based objectives, which favor languages dominant in the training data and consequently…

Computation and Language · Computer Science 2025-08-25 Negar Foroutan , Clara Meister , Debjit Paul , Joel Niklaus , Sina Ahmadi , Antoine Bosselut , Rico Sennrich

The prevalent use of Byte Pair Encoding (BPE) in Large Language Models (LLMs) facilitates robust handling of subword units and avoids issues of out-of-vocabulary words. Despite its success, a critical challenge persists: long tokens, rich…

Computation and Language · Computer Science 2024-11-11 Haoran Lian , Yizhe Xiong , Zijia Lin , Jianwei Niu , Shasha Mo , Hui Chen , Peng Liu , Guiguang Ding

Tokenization is a foundational step in natural language processing (NLP) tasks, bridging raw text and language models. Existing tokenization approaches like Byte-Pair Encoding (BPE) originate from the field of data compression, and it has…

Computation and Language · Computer Science 2024-10-08 Craig W. Schmidt , Varshini Reddy , Haoran Zhang , Alec Alameddine , Omri Uzan , Yuval Pinter , Chris Tanner

Tokenization is a crucial step in processing protein sequences for machine learning models, as proteins are complex sequences of amino acids that require meaningful segmentation to capture their functional and structural properties.…

Computation and Language · Computer Science 2024-11-27 Burak Suyunu , Enes Taylan , Arzucan Özgür

This paper presents a novel hybrid tokenization strategy that enhances the performance of DNA Language Models (DLMs) by combining 6-mer tokenization with Byte Pair Encoding (BPE-600). Traditional k-mer tokenization is effective at capturing…

Computation and Language · Computer Science 2025-07-25 Ganesh Sapkota , Md Hasibur Rahman

Standard Byte-Pair Encoding (BPE) tokenization compresses text by pairing a learned token vocabulary with a detailed merge list. Recent work has shown that this merge list exposes a potential attack surface for extracting information about…

Computation and Language · Computer Science 2025-08-12 Tomohiro Sawada , Kartik Goyal

Tokenization imposes a fixed granularity on the input text, freezing how a language model operates on data and how far in the future it predicts. Byte Pair Encoding (BPE) and similar schemes split text once, build a static vocabulary, and…

Computation and Language · Computer Science 2025-06-18 Mathurin Videau , Badr Youbi Idrissi , Alessandro Leite , Marc Schoenauer , Olivier Teytaud , David Lopez-Paz

Byte pair encoding (BPE) emerges as an effective tokenization method for tackling the out-of-vocabulary (OOV) challenge in various natural language and speech processing tasks. Recent research highlights the dependency of BPE subword…

Computation and Language · Computer Science 2024-01-30 Ahnaf Mozib Samin

In this work, we show a fundamental limitation in vocabulary adaptation approaches that use Byte-Pair Encoding (BPE) tokenization scheme for fine-tuning pretrained language models (PLMs) to expert domains. Current approaches trivially…

Computation and Language · Computer Science 2025-04-29 Gunjan Balde , Soumyadeep Roy , Mainack Mondal , Niloy Ganguly

Byte-Pair Encoding (BPE) is an algorithm commonly used in Natural Language Processing to build a vocabulary of subwords, which has been recently applied to symbolic music. Given that symbolic music can differ significantly from text,…

Information Retrieval · Computer Science 2024-10-03 Dinh-Viet-Toan Le , Louis Bigo , Mikaela Keller

Pre-tokenization, the initial step in many modern tokenization pipelines, segments text into smaller units called pretokens, typically splitting on whitespace and punctuation. While this process encourages having full, individual words as…

Computation and Language · Computer Science 2025-10-03 Craig W. Schmidt , Varshini Reddy , Chris Tanner , Yuval Pinter

Sequence models for binary analysis are bottlenecked by byte-level tokenization: raw bytes waste precious context window capacity for transformers and other neural network architectures, and many existing text-oriented tokenizers fail on…

Machine Learning · Computer Science 2025-11-25 Michael J. Bommarito

When used with deep learning, the symbolic music modality is often coupled with language model architectures. To do so, the music needs to be tokenized, i.e. converted into a sequence of discrete tokens. This can be achieved by different…

Machine Learning · Computer Science 2023-11-14 Nathan Fradet , Nicolas Gutowski , Fabien Chhel , Jean-Pierre Briot
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