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Aqueous solubility and partition coefficient are important physical properties of small molecules. Accurate theoretical prediction of aqueous solubility and partition coefficient plays an important role in drug design and discovery. The…

Quantitative Methods · Quantitative Biology 2018-01-08 Kedi Wu , Zhixiong Zhao , Renxiao Wang , Guo-Wei Wei

We consider the problem of efficiently computing a discrete Morse complex on simplicial complexes of arbitrary dimension and very large size. Based on a common graph-based formalism, we analyze existing data structures for simplicial…

Computational Geometry · Computer Science 2018-11-13 Ulderico Fugacci , Federico Iuricich , Leila De Floriani

Robust estimation of object poses in robotic manipulation is often addressed using foundational general estimators, that aim to handle diverse error sources naively within a single model. Still, they struggle due to environmental…

Robotics · Computer Science 2026-03-04 Loris Schneider , Yitian Shi , Rosa Wolf , Carolin Brenner , Rudolph Triebel , Rania Rayyes

Persistent homology provides a robust methodology to infer topological structures from point cloud data. Here we explore the persistent homology of point clouds embedded into a probabilistic setting, exploiting the theory of point…

Probability · Mathematics 2023-08-07 Daniel Spitz , Anna Wienhard

We describe an algorithm for compressing a partially ordered set, or \emph{poset}, so that it occupies space matching the information theory lower bound (to within lower order terms), in the worst case. Using this algorithm, we design a…

Data Structures and Algorithms · Computer Science 2012-04-24 J. Ian Munro , Patrick K. Nicholson

We present a matrix-theoretic approach for studying and enumerating finite posets through their incidence representations, referred to as poset matrices. Naturally labelled posets are encoded as Boolean lower triangular matrices, allowing a…

Combinatorics · Mathematics 2026-02-05 Gi-Sang Cheon , Hong Joon Choi , Gukwon Kwon , Hojoon Lee , Yaling Wang

Extracting building contours from remote sensing imagery is a significant challenge due to buildings' complex and diverse shapes, occlusions, and noise. Existing methods often struggle with irregular contours, rounded corners, and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Tao Zhang , Shiqing Wei , Yikang Zhou , Muying Luo , Wenling You , Shunping Ji

A suitable feature representation that can both preserve the data intrinsic information and reduce data complexity and dimensionality is key to the performance of machine learning models. Deeply rooted in algebraic topology, persistent…

Algebraic Topology · Mathematics 2018-11-02 Chi Seng Pun , Kelin Xia , Si Xian Lee

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

A central problem in topological data analysis is that of computing the homology of a given simplicial complex. Said complexes can have arbitrary large number of simplices, as can happen, for example, if the space is the Rips-Vietoris or…

Combinatorics · Mathematics 2021-11-11 Francisco Martinez-Figueroa

Homological algebra of modules over posets is developed, as closely parallel as possible to that of finitely generated modules over noetherian commutative rings, in the direction of finite presentations and resolutions. Centrally at issue…

Algebraic Topology · Mathematics 2020-08-12 Ezra Miller

We introduce a refinement of persistent homology that detects simple-homotopy-theoretic phenomena invisible to homology. Given a filtered simplicial complex, we define the Morse complexity profile as the minimal number of critical simplices…

Algebraic Topology · Mathematics 2026-04-14 Divya Ahuja , Jaya NN Iyer

We introduce Reeb complexes in order to capture how generators of homology flow along sections of a real valued continuous function. This intuition suggests a close relation of Reeb complexes to established methods in topological data…

Algebraic Topology · Mathematics 2022-02-01 Melvin Vaupel , Erik Hermansen , Paul Trygsland

Computation of the simplicial complexes of a large point cloud often relies on extracting a sample, to reduce the associated computational burden. The study considers sampling critical points of a Morse function associated to a point cloud,…

Computer Vision and Pattern Recognition · Computer Science 2018-05-17 Charmin Asirimath , Jayampathy Ratnayake , Chathuranga Weeraddana

Proposing scoring functions to effectively understand, analyze and learn various properties of high dimensional hidden representations of large-scale transformer models like BERT can be a challenging task. In this work, we explore a new…

Machine Learning · Computer Science 2022-11-01 Jatin Chauhan , Manohar Kaul

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic

We describe and analyze a numerical algorithm for computing the homology (Betti numbers and torsion coefficients) of real projective varieties. Here numerical means that the algorithm is numerically stable (in a sense to be made precise).…

Algebraic Geometry · Mathematics 2017-05-16 Felipe Cucker , Teresa Krick , Michael Shub

We develop conjectures and theorems expressing the idea that the prime sequence exhibits computational irreducibility in the transition from one prime to its successor. Informally, given a prime pp p, no general algorithm can compute the…

Computational Complexity · Computer Science 2026-05-14 Ben Goertzel , Bill Lauritzen

Persistent homology is a method for computing the topological features present in a given data. Recently, there has been much interest in the integration of persistent homology as a computational step in neural networks or deep learning. In…

Machine Learning · Computer Science 2020-11-17 Padraig Corcoran , Bailin Deng

We establish several results combining discrete Morse theory and microlocal sheaf theory in the setting of finite posets and simplicial complexes. Our primary tool is a computationally tractable description of the bounded derived category…

General Topology · Mathematics 2025-06-11 Adam Brown , Ondrej Draganov