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Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

This study evaluates dynamic conformal arc (DCA) therapy as an alternative to volumetric modulated arc therapy (VMAT) for stereotactic body radiation therapy (SBRT) of lung cancer. The rationale for DCA is lower geometric complexity and…

Medical Physics · Physics 2019-05-07 Rasmus Bokrantz , Minna Wedenberg , Peter Sandwall

Within the setting of intensity modulated radiation therapy (IMRT) and the fully continuous version of IMRT called volumetric modulated radiation therapy (VMAT), we consider the problem of matching a given fluence map as well as possible in…

Medical Physics · Physics 2019-01-14 Matthew Kelly , Jacobus H. M. van Amerongen , Marleen Balvert , David Craft

We review the field of multi-criteria optimization for radiation therapy treatment planning. Special attention is given to the technique known as Pareto surface navigation, which allows physicians and treatment planners to interactively…

Optimization and Control · Mathematics 2013-05-08 David Craft

This paper introduces a modular and scalable design optimization framework for the glider wing design process that enables faster early-phase design while ensuring aerodynamic stability. The pipeline starts with the generation of initial…

Neural and Evolutionary Computing · Computer Science 2026-05-06 Arash Fath Lipaei , AmirHossein Ghaemi , Melika Sabzikari

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

We argue that lattice simulations of full QCD with varying quark mass are best conducted at fixed lattice spacing rather than at fixed $\beta$. We present techniques which enable this to be carried out effectively, namely the tuning in bare…

High Energy Physics - Lattice · Physics 2009-10-31 Alan C. Irving , UKQCD Collaboration

Optimized topology of bi-material acoustic metamaterial lattice plates is studied for maximized locally resonant bandgap of flexural guided waves. Optimized layout of the two relatively stiff and compliant material phases in the design…

Classical Physics · Physics 2016-11-22 Saeid Hedayatrasa , Kazem Abhary , Mohammad Uddin

The purpose of this work is two-fold. First, we introduce an efficient homogenization-based approach to perform topology optimization of coated structures with orthotropic infill material. By making use of the relaxed design space, we can…

Computational Engineering, Finance, and Science · Computer Science 2018-08-15 Jeroen Groen , Jun Wu , Ole Sigmund

The COntractor REnormalization group (CORE) approximation, a new method for solving Hamiltonian lattice systems, is introduced. The approach combines variational and contraction techniques with the real-space renormalization group approach…

High Energy Physics - Lattice · Physics 2007-05-23 Colin Morningstar , Marvin Weinstein

A Fourier-space based design approach for the systematic control of single and multiple photon localization states in a 1D lattice is presented. Resultant lattices are aperiodic in nature, such that lattice periodicity is not a useful…

Particle Therapy (PT) has emerged as a powerful tool in cancer treatment, leveraging the unique dose distribution of charged particles to deliver high radiation levels to the tumor while minimizing damage to surrounding healthy tissue.…

Medical Physics · Physics 2025-03-06 Luana Testa

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Miao Zhu , Qiming Fu , Bo Liu , Mengxi Zhang , Bojian Li , Xiaoyan Luo , Fugen Zhou

We describe new techniques in the construction of optical lattices to realize a coherent atom-based microscope, comprised of two atomic species used as target and probe atoms, each in an independently controlled optical lattice. Precise and…

Most commercially available treatment planning systems for brachytherapy operate based on physical dose and do not incorporate fractionation or tissue-specific response. The purpose of this study is to investigate the potential for…

Medical Physics · Physics 2017-12-04 Kaelyn Seeley , I-Chow J. Hsu , Tae Min Hong , J. Adam Cunha

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously…

Medical Physics · Physics 2018-03-14 Daniel O'Connor , Dan Nguyen , Dan Ruan , Victoria Yu , Ke Sheng

In cardiac magnetic resonance (CMR) imaging, a 3D high-resolution segmentation of the heart is essential for detailed description of its anatomical structures. However, due to the limit of acquisition duration and respiratory/cardiac…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Shuo Wang , Chen Qin , Nicolo Savioli , Chen Chen , Declan O'Regan , Stuart Cook , Yike Guo , Daniel Rueckert , Wenjia Bai

As depth increases, linear energy transfer (LET) rises toward the distal edge of the Bragg peak, boosting the radiobiological effectiveness (RBE). To manage the biological variation and limit normal-tissue damage, LET-modifying objective…

Medical Physics · Physics 2025-05-22 Lisa Seckler , Amit Ben Antony Bennan , Niklas Wahl

A simple scheme for communication over MIMO broadcast channels is introduced which adopts the lattice reduction technique to improve the naive channel inversion method. Lattice basis reduction helps us to reduce the average transmitted…

Information Theory · Computer Science 2016-11-15 Mahmoud Taherzadeh , Amin Mobasher , Amir K. Khandani
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