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Quantum integer factorization is a potential quantum computing solution that may revolutionize cryptography. Nevertheless, a scalable and efficient quantum algorithm for noisy intermediate-scale quantum computers looks far-fetched. We…

We propose and experimentally demonstrate sequential quantum computing (SQC), a paradigm that utilizes multiple homogeneous or heterogeneous quantum processors in hybrid classical-quantum workflows. In this manner, we are able to overcome…

Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Quantum optimization is the most mature quantum computing technology to date, providing a promising approach towards efficiently solving complex combinatorial problems. Methods such as adiabatic quantum computing (AQC) have been employed in…

Many organizations that vitally depend on computation for their competitive advantage are keen to exploit the expected performance of quantum computers (QCs) as soon as quantum advantage is achieved. The best approach to deliver hardware…

This is evident that the controllable quantum systems can be the reliable building blocks for Quantum computation. In reality we are witnessing the progress towards making the idea tractable enough, though optimistic but the threshold is…

Quantum Physics · Physics 2024-03-19 Nirupam Dutta

Adiabatic quantum computing is a universal model for quantum computing whose implementation using a gate-based quantum computer requires depths that are unreachable in the early fault-tolerant era. To mitigate the limitations of near-term…

Quantum Physics · Physics 2024-10-18 Ioannis Kolotouros , Ioannis Petrongonas , Miloš Prokop , Petros Wallden

Counterdiabatic driving emerges as a valuable technique for implementing shortcuts to adiabaticity protocols, enhancing quantum technology applications. In this context, counterdiabatic quantum computing represents a new paradigm with the…

Practical applicability of quantum optimisation on near term devices is constrained by limited qubit counts and hardware noise, which restricts the scalability of quantum optimisation algorithms for combinatorial problems. The simulation of…

Quantum Physics · Physics 2026-05-01 Namasi G Sankar , Georgios Miliotis , Simon Caton

Quantum simulation with adiabatic annealing can provide insight into difficult problems that are impossible to study with classical computers. However, it deteriorates when the systems scale up due to the shrinkage of the excitation gap and…

Molecular docking plays a pivotal role in drug discovery and precision medicine, enabling us to understand protein functions and advance novel therapeutics. Here, we introduce a potential alternative solution to this problem, the…

Quantum Physics · Physics 2024-05-17 Qi-Ming Ding , Yi-Ming Huang , Xiao Yuan

The quantum approximate optimisation algorithm was proposed as a heuristic method for solving combinatorial optimisation problems on near-term quantum computers and may be among the first algorithms to perform useful computations in the…

Quantum Physics · Physics 2022-11-10 David Headley , Thorge Müller , Ana Martin , Enrique Solano , Mikel Sanz , Frank K. Wilhelm

In machine learning, fewer features reduce model complexity. Carefully assessing the influence of each input feature on the model quality is therefore a crucial preprocessing step. We propose a novel feature selection algorithm based on a…

Quantum Physics · Physics 2023-02-22 Sascha Mücke , Raoul Heese , Sabine Müller , Moritz Wolter , Nico Piatkowski

We benchmark current annealing-based optimization workflows on a greenhouse-inspired quadratic unconstrained binary optimization problem for binary heater scheduling, where the horizon H denotes the number of hourly control decisions. For…

Quantum Physics · Physics 2026-05-28 Hamzeh Alavirad , Maryam Bahrami Zanjani

A major challenge in machine learning is the computational expense of training these models. Model training can be viewed as a form of optimization used to fit a machine learning model to a set of data, which can take up significant amount…

Machine Learning · Computer Science 2021-11-16 Prasanna Date , Thomas Potok

We introduce a digital-analog quantum computing framework that enables counterdiabatic protocols to be implemented at constant circuit depth, allowing fast and resource-efficient quantum state preparation on current quantum hardware.…

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

Over the past decade, the usefulness of quantum annealing hardware for combinatorial optimization has been the subject of much debate. Thus far, experimental benchmarking studies have indicated that quantum annealing hardware does not…

Optimization and Control · Mathematics 2022-10-11 Byron Tasseff , Tameem Albash , Zachary Morrell , Marc Vuffray , Andrey Y. Lokhov , Sidhant Misra , Carleton Coffrin

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

Major players in the global aerospace industry are shifting their focus toward achieving net carbon-neutral operations by 2050. A considerable portion of the overall carbon emission reduction is expected to come from new aircraft…