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Modelling complex multiphysics systems governed by nonlinear and strongly coupled partial differential equations (PDEs) is a cornerstone in computational science and engineering. However, it remains a formidable challenge for traditional…

Machine Learning · Computer Science 2025-02-28 Biao Yuan , He Wang , Yanjie Song , Ana Heitor , Xiaohui Chen

We construct and compare three operator learning architectures, DeepONet, Fourier Neural Operator, and Wavelet Neural Operator, in order to learn the operator mapping a time-dependent applied current to the transmembrane potential of the…

Numerical Analysis · Mathematics 2024-06-05 Edoardo Centofanti , Massimiliano Ghiotto , Luca F. Pavarino

Accurate and efficient solutions of spatiotemporal partial differential equations (PDEs), such as phase-field models, are fundamental for understanding interfacial dynamics and microstructural evolution in materials science and fluid…

Computational Physics · Physics 2026-02-19 Mostafa Bamdad , Mohammad Sadegh Eshaghi , Cosmin Anitescu , Navid Valizadeh , Timon Rabczuk

Cardiac resynchronization therapy (CRT) is a common intervention for patients with dyssynchronous heart failure, yet approximately one-third of recipients fail to respond, partly due to suboptimal lead placement. Identifying optimal pacing…

Computational Engineering, Finance, and Science · Computer Science 2026-02-13 Ehsan Naghavi , Haifeng Wang , Vahid Ziaei Rad , Julius Guccione , Ghassan Kassab , Vishnu Boddeti , Seungik Baek , Lik-Chuan Lee

The monodomain model is widely used in in-silico cardiology to describe excitation propagation in the myocardium. Frequently, operator splitting is used to decouple the stiff reaction term and the diffusion term in the monodomain model so…

Numerical Analysis · Mathematics 2021-10-14 Konstantinos A Mountris , Esther Pueyo

Neural operators approximate PDE solution maps, but they need not respect the symmetries of the governing equation. In out-of-distribution (OOD) regimes, a standard neural operator must often learn coordinate alignment and physical…

Machine Learning · Computer Science 2026-05-19 Jiaxiao Xu , Changhong Mou , Yeyu Zhang , Fengxiang He

This article presents a three-step framework for learning and solving partial differential equations (PDEs) using kernel methods. Given a training set consisting of pairs of noisy PDE solutions and source/boundary terms on a mesh, kernel…

Machine Learning · Statistics 2023-04-03 Da Long , Nicole Mrvaljevic , Shandian Zhe , Bamdad Hosseini

Operator learning seeks to approximate mappings from input functions to output solutions, particularly in the context of partial differential equations (PDEs). While recent advances such as DeepONet and Fourier Neural Operator (FNO) have…

Machine Learning · Computer Science 2025-05-27 Yile Li , Shandian Zhe

By learning the mappings between infinite function spaces using carefully designed neural networks, the operator learning methodology has exhibited significantly more efficiency than traditional methods in solving complex problems such as…

Numerical Analysis · Mathematics 2023-03-06 Ziyuan Liu , Haifeng Wang , Hong Zhang , Kaijuna Bao , Xu Qian , Songhe Song

Learning solution operators for partial differential equations (PDEs) has become a foundational task in scientific machine learning. However, existing neural operator methods require abundant training data for each specific PDE and lack the…

Machine Learning · Computer Science 2025-08-05 Yile Li , Shandian Zhe

We propose the Inverse Neural Operator (INO), a two-stage framework for recovering hidden ODE parameters from sparse, partial observations. In Stage 1, a Conditional Fourier Neural Operator (C-FNO) with cross-attention learns a…

Machine Learning · Computer Science 2026-03-13 Zhi-Song Liu , Wenqing Peng , Helmi Toropainen , Ammar Kheder , Andreas Rupp , Holger Froning , Xiaojie Lin , Michael Boy

Traditionally, neural networks have been employed to learn the mapping between finite-dimensional Euclidean spaces. However, recent research has opened up new horizons, focusing on the utilization of deep neural networks to learn operators…

Machine Learning · Computer Science 2025-02-18 Somdatta Goswami , Dimitris G. Giovanis , Bowei Li , Seymour M. J. Spence , Michael D. Shields

We introduce a method that combines neural operators, physics-informed machine learning, and standard numerical methods for solving PDEs. The proposed approach extends each of the aforementioned methods and unifies them within a single…

Computational Engineering, Finance, and Science · Computer Science 2025-12-02 Shahed Rezaei , Reza Najian Asl , Kianoosh Taghikhani , Ahmad Moeineddin , Michael Kaliske , Markus Apel

Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies, and ischaemic heart disease. However, methods to detect…

Medical Physics · Physics 2025-06-30 James A Coleman , Julia Camps , Abdallah I Hasaballa , Alfonso Bueno-Orovio

Operator learning has emerged as a promising paradigm for developing efficient surrogate models to solve partial differential equations (PDEs). However, existing approaches often overlook the domain knowledge inherent in the underlying PDEs…

Machine Learning · Computer Science 2025-10-20 Ziqian Li , Kang Liu , Yongcun Song , Hangrui Yue , Enrique Zuazua

Learning probabilistic surrogates for partial differential equations remains challenging in data-scarce regimes: neural operators require large amounts of high-fidelity data, while generative approaches typically sacrifice resolution…

Computation · Statistics 2025-12-18 Sahil Bhola , Karthik Duraisamy

Time-dependent partial differential equations are ubiquitous in physics-based modeling, but they remain computationally intensive in many-query scenarios, such as real-time forecasting, optimal control, and uncertainty quantification.…

Machine Learning · Computer Science 2026-01-26 Sven Dummer , Dongwei Ye , Christoph Brune

Neural operators have been validated as promising deep surrogate models for solving partial differential equations (PDEs). Despite the critical role of boundary conditions in PDEs, however, only a limited number of neural operators robustly…

Numerical Analysis · Mathematics 2023-12-13 Ziyuan Liu , Yuhang Wu , Daniel Zhengyu Huang , Hong Zhang , Xu Qian , Songhe Song

A kernel-based approach for the learning of the solution operator of general nonhomogeneous partial differential equations (PDEs) is proposed. The method incorporates physical priors, typically encoded through the PDE operator, into a…

Numerical Analysis · Mathematics 2026-05-12 Jianyu Hu , Juan-Pablo Ortega

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni
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