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The usefulness and value of Multi-step Machine Learning (ML), where a task is organized into connected sub-tasks with known intermediate inference goals, as opposed to a single large model learned end-to-end without intermediate sub-tasks,…

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang

Deep subspace clustering (DSC) algorithms face several challenges that hinder their widespread adoption across variois application domains. First, clustering quality is typically assessed using only the encoder's output layer, disregarding…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Lovro Sindicic , Ivica Kopriva

Events generated by the Dynamic Vision Sensor (DVS) are generally stored and processed in two-dimensional data structures whose memory complexity and energy-per-event scale proportionately with increasing sensor dimensions. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Pradeep Kumar Gopalakrishnan , Chip-Hong Chang , Arindam Basu

Dense assemblies of self propelled particles, also known as active or living glasses are abundantaround us, covering different length and time scales: from the cytoplasm to tissues, from bacterialbio-films to vehicular traffic jams, from…

Soft Condensed Matter · Physics 2022-06-08 Rituparno Mandal , Peter Sollich

Clustering single-cell RNA sequence (scRNA-seq) data poses statistical and computational challenges due to their high-dimensionality and data-sparsity, also known as `dropout' events. Recently, Regularized Auto-Encoder (RAE) based deep…

Machine Learning · Computer Science 2021-07-19 Arnab Kumar Mondal , Himanshu Asnani , Parag Singla , Prathosh AP

We present an ultra-fast, precise, parameter-free method, which we term Deep-STORM, for obtaining super-resolution images from stochastically-blinking emitters, such as fluorescent molecules used for localization microscopy. Deep-STORM uses…

Optics · Physics 2018-05-03 Elias Nehme , Lucien E. Weiss , Tomer Michaeli , Yoav Shechtman

With the rapid growth of multimedia data (e.g., image, audio and video etc.) on the web, learning-based hashing techniques such as Deep Supervised Hashing (DSH) have proven to be very efficient for large-scale multimedia search. The recent…

Information Retrieval · Computer Science 2019-01-09 Zhan Yang , Osolo Ian Raymond , Wuqing Sun , Jun Long

Distributed Acoustic Sensing (DAS) using fiber optic cables is a promising new technology for pipeline monitoring and protection. In this work, we applied and compared two approaches for event detection using DAS: Classic machine learning…

Machine Learning · Computer Science 2019-04-29 Mugdim Bublin

Single particle diffraction imaging experiments at free-electron lasers (FEL) have a great potential for structure determination of reproducible biological specimens that can not be crystallized. One of the challenges in processing the data…

Biological Physics · Physics 2013-10-16 O. M. Yefanov , I. A. Vartanyants

Recently, Convolutional Neural Networks (CNNs) have shown unprecedented success in the field of computer vision, especially on challenging image classification tasks by relying on a universal approach, i.e., training a deep model on a…

Computer Vision and Pattern Recognition · Computer Science 2019-05-23 Johan Phan , Massimiliano Ruocco , Francesco Scibilia

Generative AI foundation models offer transformative potential for processing structured biological data, particularly in single-cell RNA sequencing, where datasets are rapidly scaling toward billions of cells. We propose the use of agentic…

Genomics · Quantitative Biology 2025-06-18 Saleem A. Al Dajani , Abel Sanchez , John R. Williams

In this paper we propose a Deep Autoencoder MIxture Clustering (DAMIC) algorithm based on a mixture of deep autoencoders where each cluster is represented by an autoencoder. A clustering network transforms the data into another space and…

Machine Learning · Computer Science 2019-03-28 Shlomo E. Chazan , Sharon Gannot , Jacob Goldberger

Anchor-free detectors basically formulate object detection as dense classification and regression. For popular anchor-free detectors, it is common to introduce an individual prediction branch to estimate the quality of localization. The…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Hu Su , Yonghao He , Rui Jiang , Jiabin Zhang , Wei Zou , Bin Fan

Despite the success of deep neural network (DNN) on sequential data (i.e., scene text and speech) recognition, it suffers from the over-confidence problem mainly due to overfitting in training with the cross-entropy loss, which may make the…

Artificial Intelligence · Computer Science 2023-03-14 Shuangping Huang , Yu Luo , Zhenzhou Zhuang , Jin-Gang Yu , Mengchao He , Yongpan Wang

The recent advancements in artificial intelligence (AI), with the release of several large models having only query access, make a strong case for explainability of deep models in a post-hoc gradient free manner. In this paper, we propose a…

Artificial Intelligence · Computer Science 2024-09-18 Debarpan Bhattacharya , Amir H. Poorjam , Deepak Mittal , Sriram Ganapathy

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This…

Numerical simulation of the complex plasma dynamics associated with high power, high frequency microwave breakdown at high pressures, leading to the formation of filamentary plasma structures such as self-organized plasma arrays, is a…

Plasma Physics · Physics 2025-05-13 Pratik Ghosh , Bhaskar Chaudhury

The feasibility of deep neural networks (DNNs) to address data stream problems still requires intensive study because of the static and offline nature of conventional deep learning approaches. A deep continual learning algorithm, namely…

Machine Learning · Computer Science 2020-01-10 Andri Ashfahani , Mahardhika Pratama

Due to the high storage and search efficiency, hashing has become prevalent for large-scale similarity search. Particularly, deep hashing methods have greatly improved the search performance under supervised scenarios. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Erkun Yang , Tongliang Liu , Cheng Deng , Wei Liu , Dacheng Tao