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Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

Tissues and Organs · Quantitative Biology 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran

We study a simple model of a random walker in d dimensions moving in the presence of a local heterogeneous attracting factor expressed in terms of an assigned space-dependent "attractiveness function", a situation frequently encountered in…

Statistical Mechanics · Physics 2017-06-21 Hardi Veermäe , Marco Patriarca

A slowly-varying or thin-layer multiscale assumption empowers macroscale understanding of many physical scenarios from dispersion in pipes and rivers, including beams, shells, and the modulation of nonlinear waves, to homogenisation of…

Dynamical Systems · Mathematics 2020-01-22 A. J. Roberts

We consider a continuum aggregation model with nonlinear local repulsion given by a degenerate power-law diffusion with general exponent. The steady states and their properties in one dimension are studied both analytically and numerically,…

Analysis of PDEs · Mathematics 2014-03-17 Martin Burger , Razvan Fetecau , Yanghong Huang

Existing nonlocal diffusion models are predominantly classified into two categories: bond-based models, which involve a single-fold integral and usually simulate isotropic diffusion, and state-based models, which contain a double-fold…

Numerical Analysis · Mathematics 2024-01-11 Lili Ju , Hao Tian , Junke Lu

We developed a new self-adjoint, consistent, and stable coupling strategy for nonlocal diffusion models, inspired by the quasinonlocal atomistic-to-continuum method for crystalline solids. The proposed coupling model is coercive with…

Numerical Analysis · Mathematics 2017-02-07 Xingjie Helen Li , Jianfeng Lu

Describing particle transport at the macroscopic or mesoscopic level in non-ideal environments poses fundamental theoretical challenges in domains ranging from inter and intra-cellular transport in biology to diffusion in porous media. Yet,…

Statistical Mechanics · Physics 2013-09-11 Marta Galanti , Duccio Fanelli , Francesco Piazza

The Cahn-Hilliard equation is a fundamental model for phase separation phenomena. Its rigorous derivation from the nonlocal aggregation equation, motivated by the desire to link interacting particle systems and continuous descriptions, has…

Analysis of PDEs · Mathematics 2024-07-08 Charles Elbar , Jakub Skrzeczkowski

We investigate a class of systems of partial differential equations with nonlinear cross-diffusion and nonlocal interactions, which are of interest in several contexts in social sciences, finance, biology, and real world applications.…

Analysis of PDEs · Mathematics 2017-10-05 M. Di Francesco , A. Esposito , S. Fagioli

In 2006 Armstrong, Painter and Sherratt formulated a non-local differential equation model for cell-cell adhesion. For the one dimensional case we derive various types of adhesive, repulsive, and no-flux boundary bonditions. We prove local…

Analysis of PDEs · Mathematics 2019-03-18 Thomas Hillen , Andreas Buttenschön

In this paper, we develop an encounter-based model of partial surface adsorption for fractional diffusion in a bounded domain. We take the probability of adsorption to depend on the amount of particle-surface contact time, as specified by a…

Statistical Mechanics · Physics 2023-03-21 Paul C Bressloff

Systems describing the long-range interaction between individuals have attracted a lot of attention in the last years, in particular in relation with living systems. These systems are quadratic, written under the form of transport equations…

Analysis of PDEs · Mathematics 2023-06-13 Marie Doumic , Sophie Hecht , Benoit Perthame , Diane Peurichard

We investigate the long term behavior in terms of global attractors, as time goes to infinity, of solutions to a continuum model for biological aggregations in which individuals experience long-range social attraction and short range…

Dynamical Systems · Mathematics 2013-05-02 Ciprian G. Gal

We show that degenerate nonlinear diffusion equations can be asymptotically obtained as a limit from a class of nonlocal partial differential equations. The nonlocal equations are obtained as gradient flows of interaction-like energies…

Analysis of PDEs · Mathematics 2023-10-12 José Antonio Carrillo , Antonio Esposito , Jeremy Sheung-Him Wu

In this paper, we analyze a model composed by coupled local and nonlocal diffusion equations acting in different subdomains. We consider the limit case when one of the subdomains is thin in one direction (it is concentrated to a domain of…

Analysis of PDEs · Mathematics 2021-04-28 Bruna C. dos Santos , Sergio M. Oliva , Julio D. Rossi

Nonlocal diffusion model provides an appropriate description of the diffusion process of solute in the complex medium, which cannot be described properly by classical theory of PDE. However, the operators in the nonlocal diffusion models…

Numerical Analysis · Mathematics 2018-03-01 Hao Tian , Jing Zhang

The Gray-Scott model is a set of reaction-diffusion equations that describes chemical systems far from equilibrium. Interest in this model stems from its ability to generate spatio-temporal structures, including pulses, spots, stripes, and…

Numerical Analysis · Mathematics 2024-03-26 Loic Cappanera , Gabriela Jaramillo , Cory Ward

The main purpose of this work is the mathematical modelling of large populations of cells under different deterministic interactions among themselves, in balance with naturally random diffusion. We focus on cell-cell adhesion mechanisms for…

Analysis of PDEs · Mathematics 2025-03-19 Carlo Giambiagi Ferrari , Francisco Guillen-Gonzalez , Mayte Perez-Llanos , Antonio Suarez

This paper is concerned with a strongly degenerate convection-diffusion equation in one space dimension whose convective flux involves a non-linear function of the total mass to one side of the given position. This equation can be…

Numerical Analysis · Mathematics 2010-07-12 Fernando Betancourt , Raimund Bürger , Kenneth H. Karlsen

We present a self-contained investigation on the local and global well-posedness for a system of nonlocal advection--diffusion equations for a heterogeneous population over $\mathbb{R}^d$, $d \in \mathbb{N}$. Each convolution kernel…

Analysis of PDEs · Mathematics 2026-03-19 Joseph McCusker , John Christopher Meyer , Mabel Lizzy Rajendran