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Related papers: Assessing and Mitigating Medical Knowledge Drift a…

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A common solution for mitigating outdated or incorrect information in Large Language Models (LLMs) is to provide updated facts in-context or through knowledge editing. However, these methods introduce knowledge conflicts when the knowledge…

Artificial Intelligence · Computer Science 2026-01-23 Yiyang Feng , Zeming Chen , Haotian Wu , Jiawei Zhou , Antoine Bosselut

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Recent advancements in Large Language Models (LLMs) have positioned them as powerful tools for clinical decision-making, with rapidly expanding applications in healthcare. However, concerns about bias remain a significant challenge in the…

Artificial Intelligence · Computer Science 2024-10-23 Kenza Benkirane , Jackie Kay , Maria Perez-Ortiz

In recent years, multimodal large language models (MLLMs) have achieved significant breakthroughs, enhancing understanding across text and vision. However, current MLLMs still face challenges in effectively integrating knowledge across…

Computation and Language · Computer Science 2025-03-10 Boyu Jia , Junzhe Zhang , Huixuan Zhang , Xiaojun Wan

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir

Large Language Models (LLMs) have demonstrated strong performance in question answering (QA) tasks. However, Multi-Answer Question Answering (MAQA), where a question may have several valid answers, remains challenging. Traditional QA…

Computation and Language · Computer Science 2025-08-19 Eviatar Nachshoni , Arie Cattan , Shmuel Amar , Ori Shapira , Ido Dagan

The performance of Large Language Models (LLMs) degrades from the temporal drift between data used for model training and newer text seen during inference. One understudied avenue of language change causing data drift is the emergence of…

Computation and Language · Computer Science 2024-08-14 Jonathan Zheng , Alan Ritter , Wei Xu

Global healthcare providers are exploring use of large language models (LLMs) to provide medical advice to the public. LLMs now achieve nearly perfect scores on medical licensing exams, but this does not necessarily translate to accurate…

Large language models (LLMs) are rapidly transitioning into medical clinical use, yet their reliability under realistic, multi-turn interactions remains poorly understood. Existing evaluation frameworks typically assess single-turn question…

Computation and Language · Computer Science 2025-10-15 Blazej Manczak , Eric Lin , Francisco Eiras , James O' Neill , Vaikkunth Mugunthan

The rise of large language models (LLMs) has significantly influenced the quality of information in decision-making systems, leading to the prevalence of AI-generated content and challenges in detecting misinformation and managing…

Computation and Language · Computer Science 2024-10-08 Cheng Jiayang , Chunkit Chan , Qianqian Zhuang , Lin Qiu , Tianhang Zhang , Tengxiao Liu , Yangqiu Song , Yue Zhang , Pengfei Liu , Zheng Zhang

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

Computation and Language · Computer Science 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Retrieval Augmented Generation (RAG) is a commonly used approach for enhancing large language models (LLMs) with relevant and up-to-date information. However, the retrieved sources can often contain conflicting information and it remains…

Computation and Language · Computer Science 2025-06-17 Arie Cattan , Alon Jacovi , Ori Ram , Jonathan Herzig , Roee Aharoni , Sasha Goldshtein , Eran Ofek , Idan Szpektor , Avi Caciularu

With the development of large language models (LLMs) like the GPT series, their widespread use across various application scenarios presents a myriad of challenges. This review initially explores the issue of domain specificity, where LLMs…

Computation and Language · Computer Science 2023-10-23 Xiaoliang Chen , Liangbin Li , Le Chang , Yunhe Huang , Yuxuan Zhao , Yuxiao Zhang , Dinuo Li

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

The transition of Large Language Models (LLMs) from passive knowledge retrievers to autonomous clinical agents demands a shift in evaluation-from static accuracy to dynamic behavioral reliability. To explore this boundary in dentistry, a…

Computation and Language · Computer Science 2026-01-21 Hongyang Ma , Tiantian Gu , Huaiyuan Sun , Huilin Zhu , Yongxin Wang , Jie Li , Wubin Sun , Zeliang Lian , Yinghong Zhou , Yi Gao , Shirui Wang , Zhihui Tang

Large language models (LLMs) show promise in drafting responses to patient portal messages, yet their integration into clinical workflows raises various concerns, including whether they would actually save clinicians time and effort in…

Computation and Language · Computer Science 2026-01-19 Parker Seegmiller , Joseph Gatto , Sarah E. Greer , Ganza Belise Isingizwe , Rohan Ray , Timothy E. Burdick , Sarah Masud Preum

Large Language Models (LLMs) are increasingly deployed in high-stakes domains such as clinical decision support and medical documentation. However, the robustness of these models against subtle linguistic variations, specifically…

Computation and Language · Computer Science 2026-05-19 Jen-tse Huang , Didi Zhou , Faith Kamau , Amy Oh , Anne R. Links , Mark Dredze , Mary Catherine Beach , Somnath Saha