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Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes…

Computation and Language · Computer Science 2024-02-07 Jaewoong Kim , Moohong Min

Large language models achieve high task performance yet often hallucinate or rely on outdated knowledge. Retrieval-augmented generation (RAG) addresses these gaps by coupling generation with external search. We analyse how hyperparameters…

Machine Learning · Computer Science 2025-05-14 Adel Ammar , Anis Koubaa , Omer Nacar , Wadii Boulila

Purpose: Large Language Models (LLMs) hold significant promise for medical applications. Retrieval Augmented Generation (RAG) emerges as a promising approach for customizing domain knowledge in LLMs. This case study presents the development…

Organizations increasingly rely on proprietary enterprise data, including HR records, structured reports, and tabular documents, for critical decision-making. While Large Language Models (LLMs) have strong generative capabilities, they are…

Computation and Language · Computer Science 2025-07-17 Chandana Cheerla

Retrieval-augmented generation (RAG) systems address complex user requests by decomposing them into subqueries, retrieving potentially relevant documents for each, and then aggregating them to generate an answer. Efficiently selecting…

Artificial Intelligence · Computer Science 2025-10-22 Roxana Petcu , Kenton Murray , Daniel Khashabi , Evangelos Kanoulas , Maarten de Rijke , Dawn Lawrie , Kevin Duh

This systematic review of the research literature on retrieval-augmented generation (RAG) provides a focused analysis of the most highly cited studies published between 2020 and May 2025. A total of 128 articles met our inclusion criteria.…

Digital Libraries · Computer Science 2025-09-10 Andrew Brown , Muhammad Roman , Barry Devereux

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Retrieval-augmented generation (RAG) techniques leverage the in-context learning capabilities of large language models (LLMs) to produce more accurate and relevant responses. Originating from the simple 'retrieve-then-read' approach, the…

Computation and Language · Computer Science 2024-07-16 Yunxiao Shi , Xing Zi , Zijing Shi , Haimin Zhang , Qiang Wu , Min Xu

Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plans. Methods and Materials: We curated a multi-protocol…

With the rapid development of Large Language Models (LLMs), Retrieval-Augmented Generation (RAG) has become a predominant method in the field of professional knowledge-based question answering. Presently, major foundation model companies…

Artificial Intelligence · Computer Science 2024-01-24 Demiao Lin

Medical question answering (QA) is a reasoning-intensive task that remains challenging for large language models (LLMs) due to hallucinations and outdated domain knowledge. Retrieval-Augmented Generation (RAG) provides a promising…

Computation and Language · Computer Science 2025-05-01 Xuanzhao Dong , Wenhui Zhu , Hao Wang , Xiwen Chen , Peijie Qiu , Rui Yin , Yi Su , Yalin Wang

Proprietary corporate documents contain rich domain-specific knowledge, but their overwhelming volume and disorganized structure make it difficult even for employees to access the right information when needed. For example, in the…

Artificial Intelligence · Computer Science 2025-08-28 Nayoung Choi , Grace Byun , Andrew Chung , Ellie S. Paek , Shinsun Lee , Jinho D. Choi

This study aims to improve the accuracy and quality of large-scale language models (LLMs) in answering questions by integrating Elasticsearch into the Retrieval Augmented Generation (RAG) framework. The experiment uses the Stanford Question…

Information Retrieval · Computer Science 2024-10-21 Jiajing Chen , Runyuan Bao , Hongye Zheng , Zhen Qi , Jianjun Wei , Jiacheng Hu

Given the growing trend of many organizations integrating Retrieval Augmented Generation (RAG) into their operations, we assess RAG on domain-specific data and test state-of-the-art models across various optimization techniques. We…

Artificial Intelligence · Computer Science 2024-11-14 Anum Afzal , Juraj Vladika , Gentrit Fazlija , Andrei Staradubets , Florian Matthes

Retrieval-Augmented Generation (RAG) is a prevalent approach to infuse a private knowledge base of documents with Large Language Models (LLM) to build Generative Q\&A (Question-Answering) systems. However, RAG accuracy becomes increasingly…

Information Retrieval · Computer Science 2025-03-10 Kunal Sawarkar , Abhilasha Mangal , Shivam Raj Solanki

Retrieval-Augmented Generation (RAG) systems have recently shown remarkable advancements by integrating retrieval mechanisms into language models, enhancing their ability to produce more accurate and contextually relevant responses.…

Computation and Language · Computer Science 2025-01-14 Siran Li , Linus Stenzel , Carsten Eickhoff , Seyed Ali Bahrainian

Retrieval Augmented Generation (RAG) is a common method for integrating external knowledge into pretrained Large Language Models (LLMs) to enhance accuracy and relevancy in question answering (QA) tasks. However, prompt engineering and…

Computation and Language · Computer Science 2024-10-18 Isaac Chung , Phat Vo , Arman C. Kizilkale , Aaron Reite

A Comparison of Independent and Joint Fine-tuning Strategies for Retrieval-Augmented Generation Download PDF Neal Gregory Lawton, Alfy Samuel, Anoop Kumar, Daben Liu Published: 20 Aug 2025, Retrieval augmented generation (RAG) is a popular…

Computation and Language · Computer Science 2025-10-21 Neal Gregory Lawton , Alfy Samuel , Anoop Kumar , Daben Liu

Retrieval-Augmented Generation (RAG) is increasingly employed in generative AI-driven scientific workflows to integrate rapidly evolving scientific knowledge bases, yet its reliability is frequently compromised by non-determinism in their…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-24 Baiqiang Wang , Dongfang Zhao , Nathan R Tallent , Luanzheng Guo