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This paper describes a multi-modal approach for the automatic detection of Alzheimer's disease proposed in the context of the INESC-ID Human Language Technology Laboratory participation in the ADReSS 2020 challenge. Our classification…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-01 Anna Pompili , Thomas Rolland , Alberto Abad

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Gene regulation is a dynamic process that connects genotype and phenotype. Given the difficulty of physically mapping mammalian gene circuitry, we require new computational methods to learn regulatory rules. Natural language is a valuable…

Quantitative Methods · Quantitative Biology 2022-10-27 William Connell , Umair Khan , Michael J. Keiser

The field of learning analytics has made notable strides in automating the detection of complex learning processes in multimodal data. However, most advancements have focused on individualized problem-solving instead of collaborative,…

As queries in retrieval-augmented generation (RAG) pipelines powered by large language models (LLMs) become increasingly complex and diverse, dense retrieval models have demonstrated strong performance in semantic matching. Nevertheless,…

Information Retrieval · Computer Science 2025-09-30 Shaoxiong Zhan , Hai Lin , Hongming Tan , Xiaodong Cai , Hai-Tao Zheng , Xin Su , Zifei Shan , Ruitong Liu , Hong-Gee Kim

Large decoder-only language models (LLMs) have achieved remarkable success in generation and reasoning tasks, where they generate text responses given instructions. However, many applications, e.g., retrieval augmented generation (RAG),…

Computation and Language · Computer Science 2025-06-06 Caojin Zhang , Qiang Zhang , Ke Li , Sai Vidyaranya Nuthalapati , Benyu Zhang , Jason Liu , Serena Li , Lizhu Zhang , Xiangjun Fan

This study demonstrates that generative large language models can be utilized in a more flexible manner for DNA sequence analysis and classification tasks compared to traditional transformer encoder-based models. While recent encoder-based…

Computation and Language · Computer Science 2025-03-07 Hyunwoo Yoo

This study investigates the internal representations of verb-particle combinations within transformer-based large language models (LLMs), specifically examining how these models capture lexical and syntactic nuances at different neural…

Computation and Language · Computer Science 2024-12-20 Hassane Kissane , Achim Schilling , Patrick Krauss

In the current literature, most embedding models are based on the encoder-only transformer architecture to extract a dense and meaningful representation of the given input, which can be a text, an image, and more. With the recent advances…

Computation and Language · Computer Science 2025-03-18 Elio Musacchio , Lucia Siciliani , Pierpaolo Basile , Giovanni Semeraro

Large Language Models (LLMs) excel in various natural language processing tasks, but leveraging them for dense passage embedding remains challenging. This is due to their causal attention mechanism and the misalignment between their…

Computation and Language · Computer Science 2024-08-08 Hieu Man , Nghia Trung Ngo , Franck Dernoncourt , Thien Huu Nguyen

Pre-trained transformer models shine in many natural language processing tasks and therefore are expected to bear the representation of the input sentence or text meaning. These sentence-level embeddings are also important in…

Computation and Language · Computer Science 2025-02-21 Lukas Stankevičius , Mantas Lukoševičius

Multimodal signals, including text, audio, image, and video, can be integrated into Semantic Communication (SC) systems to provide an immersive experience with low latency and high quality at the semantic level. However, the multimodal SC…

Artificial Intelligence · Computer Science 2024-08-06 Feibo Jiang , Li Dong , Yubo Peng , Kezhi Wang , Kun Yang , Cunhua Pan , Xiaohu You

A large-scale knowledge graph enhances reproducibility in biomedical data discovery by providing a standardized, integrated framework that ensures consistent interpretation across diverse datasets. It improves generalizability by connecting…

Methodology · Statistics 2024-10-11 Suqi Liu , Tianxi Cai , Xiaoou Li

We present four main contributions to enhance the performance of Large Language Models (LLMs) in generating domain-specific code: (i) utilizing LLM-based data splitting and data renovation techniques to improve the semantic representation…

Computation and Language · Computer Science 2024-01-31 Yu-Chen Lin , Akhilesh Kumar , Norman Chang , Wenliang Zhang , Muhammad Zakir , Rucha Apte , Haiyang He , Chao Wang , Jyh-Shing Roger Jang

Modeling the dynamics of cellular differentiation is fundamental to advancing the understanding and treatment of diseases associated with this process, such as cancer. With the rapid growth of single-cell datasets, this has also become a…

Understanding how the human brain progresses from processing simple linguistic inputs to performing high-level reasoning is a fundamental challenge in neuroscience. While modern large language models (LLMs) are increasingly used to model…

Computation and Language · Computer Science 2026-01-27 Linyang He , Tianjun Zhong , Richard Antonello , Gavin Mischler , Micah Goldblum , Nima Mesgarani

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Artificial Intelligence · Computer Science 2025-11-17 Tiantian He , An Zhao , Elinor Thompson , Anna Schroder , Ahmed Abdulaal , Frederik Barkhof , Daniel C. Alexander

Semantic sentence embedding models encode natural language sentences into vectors, such that closeness in embedding space indicates closeness in the semantics between the sentences. Bilingual data offers a useful signal for learning such…

Computation and Language · Computer Science 2020-11-20 John Wieting , Graham Neubig , Taylor Berg-Kirkpatrick

Pretrained language models (PLMs) form the basis of most state-of-the-art NLP technologies. Nevertheless, they are essentially black boxes: Humans do not have a clear understanding of what knowledge is encoded in different parts of the…

Computation and Language · Computer Science 2023-11-15 Tanja Baeumel , Soniya Vijayakumar , Josef van Genabith , Guenter Neumann , Simon Ostermann

Understanding how explicit theoretical features are encoded in opaque neural systems is a central challenge now common to neuroscience and AI. We introduce Metric Learning Encoding Models (MLEMs) to address this challenge most directly as a…

Computation and Language · Computer Science 2025-11-17 Louis Jalouzot , Christophe Pallier , Emmanuel Chemla , Yair Lakretz