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Counterfactual reasoning is widely recognized as one of the most challenging and intricate aspects of causality in artificial intelligence. In this paper, we evaluate the performance of large language models (LLMs) in counterfactual…

Computation and Language · Computer Science 2026-04-14 Yuefei Chen , Vivek K. Singh , Jing Ma , Ruixiang Tang

Physics problem-solving is a challenging domain for AI models, requiring integration of conceptual understanding, mathematical reasoning, and interpretation of physical diagrams. Existing evaluations fail to capture the full breadth and…

Artificial Intelligence · Computer Science 2026-02-12 Lintao Wang , Encheng Su , Jiaqi Liu , Pengze Li , Jiabei Xiao , Wenlong Zhang , Xinnan Dai , Xi Chen , Yuan Meng , Lei Bai , Wanli Ouyang , Shixiang Tang , Aoran Wang , Xinzhu Ma

While large language models (LLMs) can solve PhD-level reasoning problems over long context inputs, they still struggle with a seemingly simpler task: following explicit length instructions-e.g., write a 10,000-word novel. Additionally,…

Computation and Language · Computer Science 2025-06-12 Wei Zhang , Zhenhong Zhou , Kun Wang , Junfeng Fang , Yuanhe Zhang , Rui Wang , Ge Zhang , Xavier Li , Li Sun , Lingjuan Lyu , Yang Liu , Sen Su

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks. However, their ability to reliably reason from gene-level knowledge to functional understanding, a core…

Genomics · Quantitative Biology 2026-05-25 Xiaohan Huang , Meng Xiao , Chuan Qin , Qingqing Long , Jinmiao Chen , Yuanchun Zhou , Hengshu Zhu

As Large Language Models (LLMs) advance toward embodied AI agents operating in physical environments, a fundamental question emerges: can models trained on text corpora reliably reason about complex physics while adhering to safety…

Artificial Intelligence · Computer Science 2026-04-13 Yalun Wu , Haotian Liu , Zhoujun Li , Boyang Wang

Pursuing artificial intelligence for biomedical science, a.k.a. AI Scientist, draws increasing attention, where one common approach is to build a copilot agent driven by Large Language Models (LLMs). However, to evaluate such systems,…

Computation and Language · Computer Science 2024-07-02 Xinna Lin , Siqi Ma , Junjie Shan , Xiaojing Zhang , Shell Xu Hu , Tiannan Guo , Stan Z. Li , Kaicheng Yu

In the rapidly evolving field of artificial intelligence, large language models (LLMs) have emerged as powerful tools for a myriad of applications, from natural language processing to decision-making support systems. However, as these…

Computation and Language · Computer Science 2025-07-08 Jianchao Ji , Yutong Chen , Mingyu Jin , Wujiang Xu , Wenyue Hua , Yongfeng Zhang

Causal inference in social science relies on end-to-end, intervention-centered research-design reasoning grounded in real-world policy interventions, but current benchmarks fail to evaluate this capability of large language models (LLMs).…

Frontier model progress is often measured by academic benchmarks, which offer a limited view of performance in real-world professional contexts. Existing evaluations often fail to assess open-ended, economically consequential tasks in…

The rapid evolution of large language models (LLMs) has expanded their capabilities from basic dialogue to advanced scientific reasoning. However, existing benchmarks in biology often fail to assess a critical skill required of researchers:…

Artificial Intelligence · Computer Science 2026-02-06 Junting Zhou , Jin Chen , Linfeng Hao , Denghui Cao , Zheyu Wang , Qiguang Chen , Chaoyou Fu , Jiaze Chen , Yuchen Wu , Ge Zhang , Mingxuan Wang , Wenhao Huang , Tong Yang

Large Language Models (LLMs) are transforming diverse fields and gaining increasing influence as human proxies. This development underscores the urgent need for evaluating value orientations and understanding of LLMs to ensure their…

Computation and Language · Computer Science 2024-06-07 Yuanyi Ren , Haoran Ye , Hanjun Fang , Xin Zhang , Guojie Song

As language models (LMs) evolve from chat assistants to long-horizon agents capable of multi-step reasoning and tool use, existing benchmarks remain largely confined to structured or exam-style tasks that fall short of real-world…

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

There is an increasing body of work using Large Language Models (LLMs) as agents for orchestrating workflows and making decisions in domains that require planning and multi-step reasoning. As a result, it is imperative to evaluate LLMs on…

Artificial Intelligence · Computer Science 2026-03-03 Harsha Kokel , Michael Katz , Kavitha Srinivas , Shirin Sohrabi

Multimodal Large Language Models (LLMs) hold promise for biomedical reasoning, but current benchmarks fail to capture the complexity of real-world clinical workflows. Existing evaluations primarily assess unimodal, decontextualized…

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

This paper introduces LongBench v2, a benchmark designed to assess the ability of LLMs to handle long-context problems requiring deep understanding and reasoning across real-world multitasks. LongBench v2 consists of 503 challenging…

Computation and Language · Computer Science 2025-01-06 Yushi Bai , Shangqing Tu , Jiajie Zhang , Hao Peng , Xiaozhi Wang , Xin Lv , Shulin Cao , Jiazheng Xu , Lei Hou , Yuxiao Dong , Jie Tang , Juanzi Li

We introduce seqBench, a parametrized benchmark for probing sequential reasoning limits in Large Language Models (LLMs) through precise, multi-dimensional control over several key complexity dimensions. seqBench allows systematic variation…

Artificial Intelligence · Computer Science 2025-09-23 Mohammad Ramezanali , Mo Vazifeh , Paolo Santi