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Scientific discovery catalyzes human intellectual advances, driven by the cycle of hypothesis generation, experimental design, evaluation, and assumption refinement. Central to this process is causal inference, uncovering the mechanisms…

Machine Learning · Computer Science 2025-09-26 Ivaxi Sheth , Sahar Abdelnabi , Mario Fritz

This is an up-to-date introduction to, and overview of, marginal likelihood computation for model selection and hypothesis testing. Computing normalizing constants of probability models (or ratio of constants) is a fundamental issue in many…

Computation · Statistics 2023-02-13 Fernando Llorente , Luca Martino , David Delgado , Javier Lopez-Santiago

Compelling arguments suggest the presence of new physics at energy scales that will be probed by frontier energy colliders over the next decade. Arguments for each of the many flavors of new physics that have been proposed seem much less…

High Energy Physics - Experiment · Physics 2014-11-17 Bruce Knuteson

The issue addressed in this paper is that of testing for common breaks across or within equations of a multivariate system. Our framework is very general and allows integrated regressors and trends as well as stationary regressors. The null…

Statistics Theory · Mathematics 2018-01-12 Tatsushi Oka , Pierre Perron

We describe a method for fitting distributions to data which only requires knowledge of the parametric form of either the signal or the background but not both. The unknown distribution is fit using a non-parametric kernel density…

Data Analysis, Statistics and Probability · Physics 2015-06-03 Wolfgang A. Rolke , Angel M. López

The sensitivity of direct searches for heavy neutral leptons (HNLs) in accelerator-based experiments depends strongly on the particles properties. Commonly used benchmark scenarios are important to ensure comparability and consistency…

High Energy Physics - Phenomenology · Physics 2023-01-18 Marco Drewes , Juraj Klarić , Jacobo López-Pavón

Neutrino experiments study the least understood of the Standard Model particles by observing their direct interactions with matter or searching for ultra-rare signals. The study of neutrinos typically requires overcoming large backgrounds,…

Computational Physics · Physics 2020-12-30 Fernanda Psihas , Micah Groh , Christopher Tunnell , Karl Warburton

Advances in machine learning have led to an emergence of new paradigms in the analysis of large data which could assist traditional approaches in the search for new physics amongst the immense Standard Model backgrounds at the Large Hadron…

High Energy Physics - Experiment · Physics 2017-12-12 Chang-Wei Loh , Rui Zhang , Yong-Heng Xu , Zhi-Qiang Qian , Si-Cheng Chen , He-Yang Long , You-Hang Liu , De-Wen Cao , Wei Wang , Ming Qi

This paper presents a general framework for estimating high-dimensional conditional latent factor models via constrained nuclear norm regularization. We establish large sample properties of the estimators and provide efficient algorithms…

Econometrics · Economics 2025-12-09 Qihui Chen

This paper presents a simplified likelihood framework designed to facilitate the reuse, reinterpretation and combination of LHC experimental results. The framework is based on the same underlying structure as the widely used HistFactory…

High Energy Physics - Experiment · Physics 2023-05-18 Nicolas Berger

The design of optimal test statistics is a key task in frequentist statistics and for a number of scenarios optimal test statistics such as the profile-likelihood ratio are known. By turning this argument around we can find the profile…

Methodology · Statistics 2022-03-25 Lukas Heinrich

In high-energy physics (HEP), both the exclusion and discovery of new theories depend not only on the acquisition of high-quality experimental data but also on the rigorous application of statistical methods. These methods provide…

High Energy Physics - Phenomenology · Physics 2024-11-04 Alejandro Segura , Angie Catalina Parra

We propose a rigorous and effective way to compare experimental and theoretical histograms, incorporating the different sources of statistical and systematic uncertainties. This is a useful tool to extract as much information as possible…

High Energy Physics - Phenomenology · Physics 2015-03-19 M. E. Cabrera , J. A. Casas , V. A. Mitsou , R. Ruiz de Austri , J. Terron

This study develops a framework for testing hypotheses on structural parameters in incomplete models. Such models make set-valued predictions and hence do not generally yield a unique likelihood function. The model structure, however,…

Econometrics · Economics 2019-12-03 Hiroaki Kaido , Yi Zhang

Crucial to many measurements at the LHC is the use of correlated multi-dimensional information to distinguish rare processes from large backgrounds, which is complicated by the poor modeling of many of the crucial backgrounds in Monte Carlo…

High Energy Physics - Phenomenology · Physics 2025-11-26 Oz Amram , Manuel Szewc

Most classification algorithms used in high energy physics fall under the category of supervised machine learning. Such methods require a training set containing both signal and background events and are prone to classification errors…

Data Analysis, Statistics and Probability · Physics 2015-06-03 Mikael Kuusela , Tommi Vatanen , Eric Malmi , Tapani Raiko , Timo Aaltonen , Yoshikazu Nagai

Prompt isolated leptons are essential in many analyses in high-energy particle physics but are subject to fake-lepton background, i.e. objects that mimic the lepton signature. The fake-lepton background is difficult to estimate from…

High Energy Physics - Phenomenology · Physics 2022-07-25 Johannes Erdmann , Cornelius Grunwald , Kevin Kröninger , Salvatore La Cagnina , Lars Röhrig , Erich Varnes

Motivated by real-world situations found in high energy particle physics, we consider a generalisation of the likelihood-ratio estimation task to a quasiprobabilistic setting where probability densities can be negative. By extension, this…

Machine Learning · Statistics 2024-10-15 Matthew Drnevich , Stephen Jiggins , Judith Katzy , Kyle Cranmer

The statistics and machine learning communities have recently seen a growing interest in classification-based approaches to two-sample testing. The outcome of a classification-based two-sample test remains a rejection decision, which is not…

Statistics Theory · Mathematics 2022-11-15 Loris Michel , Jeffrey Näf , Nicolai Meinshausen

Generalized linear mixed models (GLMMs) are used to model responses from exponential families with a combination of fixed and random effects. For variance components in GLMMs, we propose an approximate restricted likelihood ratio test that…

Methodology · Statistics 2019-06-11 Stephanie T. Chen , Luo Xiao , Ana-Maria Staicu