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In clinical settings, we often face the challenge of building prediction models based on small observational data sets. For example, such a data set might be from a medical center in a multi-center study. Differences between centers might…

Sepsis is a major cause of mortality in the intensive care units (ICUs). Early intervention of sepsis can improve clinical outcomes for sepsis patients. Machine learning models have been developed for clinical recognition of sepsis. A…

Applications · Statistics 2021-05-21 Jifan Gao , Philip L. Mar , Guanhua Chen

We develop new algorithms for estimating heterogeneous treatment effects, combining recent developments in transfer learning for neural networks with insights from the causal inference literature. By taking advantage of transfer learning,…

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

We aim to create a framework for transfer learning using latent factor models to learn the dependence structure between a larger source dataset and a target dataset. The methodology is motivated by our goal of building a risk-assessment…

Machine Learning · Statistics 2016-12-05 Elizabeth C Lorenzi , Zhifei Sun , Erich Huang , Ricardo Henao , Katherine A Heller

Modern precision medicine aims to utilize real-world data to provide the best treatment for an individual patient. An individualized treatment rule (ITR) maps each patient's characteristics to a recommended treatment scheme that maximizes…

Applications · Statistics 2025-01-07 Andong Wang , Kelly Wentzlof , Johnny Rajala , Miontranese Green , Yunshu Zhang , Shu Yang

Transfer learning enhances model performance in a target population with limited samples by leveraging knowledge from related studies. While many works focus on improving predictive performance, challenges of statistical inference persist.…

Methodology · Statistics 2024-12-05 Daoyuan Lai , Oscar Hernan Madrid Padilla , Tian Gu

Sepsis remains a critical challenge due to its high mortality and complex prognosis. To address data limitations in studying MSSA sepsis, we extend existing transfer learning frameworks to accommodate transformation models for…

Applications · Statistics 2025-04-16 Nan Qiao , Haowei Jiang , Cunjie Lin

Typical cohorts in brain imaging studies are not large enough for systematic testing of all the information contained in the images. To build testable working hypotheses, investigators thus rely on analysis of previous work, sometimes…

Reweighting a distribution to minimize a distance to a target distribution is a powerful and flexible strategy for estimating a wide range of causal effects, but can be challenging in practice because optimal weights typically depend on…

Machine Learning · Statistics 2026-02-16 Oscar Clivio , Avi Feller , Chris Holmes

We present a Transfer Causal Learning (TCL) framework when target and source domains share the same covariate/feature spaces, aiming to improve causal effect estimation accuracy in limited data. Limited data is very common in medical…

Machine Learning · Computer Science 2024-01-02 Song Wei , Hanyu Zhang , Ronald Moore , Rishikesan Kamaleswaran , Yao Xie

Transfer learning from ImageNet is the go-to approach when applying deep learning to medical images. The approach is either to fine-tune a pre-trained model or use it as a feature extractor. Most modern architecture contain batch…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Fahdi Kanavati , Masayuki Tsuneki

Transfer learning is a widely used method to build high performing computer vision models. In this paper, we study the efficacy of transfer learning by examining how the choice of data impacts performance. We find that more pre-training…

Computer Vision and Pattern Recognition · Computer Science 2018-12-13 Jiquan Ngiam , Daiyi Peng , Vijay Vasudevan , Simon Kornblith , Quoc V. Le , Ruoming Pang

Leveraging machine learning techniques for Sepsis early detection and diagnosis has attracted increasing interest in recent years. However, most existing methods require a large amount of labeled training data, which may not be available…

Machine Learning · Computer Science 2023-03-07 Ruiqing Ding , Yu Zhou , Jie Xu , Yan Xie , Qiqiang Liang , He Ren , Yixuan Wang , Yanlin Chen , Leye Wang , Man Huang

A key assumption in supervised learning is that training and test data follow the same probability distribution. However, this fundamental assumption is not always satisfied in practice, e.g., due to changing environments, sample selection…

Machine Learning · Computer Science 2021-12-21 Nan Lu , Tianyi Zhang , Tongtong Fang , Takeshi Teshima , Masashi Sugiyama

Randomized clinical trials are the gold standard for analyzing treatment effects, but high costs and ethical concerns can limit recruitment, potentially leading to invalid inferences. Incorporating external trial data with similar…

Methodology · Statistics 2024-09-09 Yujia Gu , Hanzhong Liu , Wei Ma

Background: Breast cancer has the highest prevalence in women globally. The classification and diagnosis of breast cancer and its histopathological images have always been a hot spot of clinical concern. In Computer-Aided Diagnosis (CAD),…

Computer Vision and Pattern Recognition · Computer Science 2022-05-11 Yuchao Zheng , Chen Li , Xiaomin Zhou , Haoyuan Chen , Hao Xu , Yixin Li , Haiqing Zhang , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

Detailed mobile sensing data from phones, watches, and fitness trackers offer an unparalleled opportunity to quantify and act upon previously unmeasurable behavioral changes in order to improve individual health and accelerate responses to…

Machine Learning · Computer Science 2022-06-06 Mike A. Merrill , Tim Althoff

We propose a novel adaptive transfer learning framework, learning to transfer learn (L2TL), to improve performance on a target dataset by careful extraction of the related information from a source dataset. Our framework considers…

Machine Learning · Computer Science 2020-07-17 Linchao Zhu , Sercan O. Arik , Yi Yang , Tomas Pfister

High-dimensional data in modern applications, such as COVID-19 mortality, often span multiple domains. Leveraging auxiliary information from source domains to improve performance in a target domain motivates the use of transfer learning.…

Methodology · Statistics 2026-04-09 Haoming Shi , Yang Feng , Xiaoqian Liu
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