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Model merging, which combines multiple models into a single model, has gained popularity in recent years. By efficiently integrating the capabilities of various models, this significantly reduces the parameter count and memory usage.…

Machine Learning · Computer Science 2025-02-11 Weiyu Chen , James Kwok

Imbalanced classification problems are extremely common in natural language processing and are solved using a variety of resampling and filtering techniques, which often involve making decisions on how to select training data or decide…

Computation and Language · Computer Science 2022-09-02 Ryan Muther , David Smith

In order to design broadband extreme ultraviolet multilayers with many objectives, the multiobjective genetic algorithm and the multiobjective genetics algorithm with reference direction have been improved and combined used. The certain…

Optics · Physics 2020-08-17 Shang-qi Kuang , Xiao-wei Song , Jing-quan Lin

While first-principles methods have been successfully applied to characterize individual properties of multi-principal element alloys (MPEA), their use to search for optimal trade-offs between competing properties is hampered by high…

Materials Science · Physics 2024-07-25 Franco Moitzi , Lorenz Romaner , Max Hodapp , Andrei V. Ruban , Oleg E. Peil

Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a truly optimal dose. because early response is not a perfect…

Applications · Statistics 2024-04-03 Cheng-Han Yang , Peter F. Thall , Ruitao Lin

Automatic Chemical Design is a framework for generating novel molecules with optimized properties. The original scheme, featuring Bayesian optimization over the latent space of a variational autoencoder, suffers from the pathology that it…

Machine Learning · Statistics 2019-08-13 Ryan-Rhys Griffiths , José Miguel Hernández-Lobato

Machine learning applications frequently come with multiple diverse objectives and constraints that can change over time. Accordingly, trained models can be tuned with sets of hyper-parameters that affect their predictive behavior (e.g.,…

Machine Learning · Computer Science 2022-10-17 Bracha Laufer-Goldshtein , Adam Fisch , Regina Barzilay , Tommi Jaakkola

The efficient exploration of chemical space to design molecules with intended properties enables the accelerated discovery of drugs, materials, and catalysts, and is one of the most important outstanding challenges in chemistry. Encouraged…

Computational Engineering, Finance, and Science · Computer Science 2023-10-12 AkshatKumar Nigam , Robert Pollice , Gary Tom , Kjell Jorner , John Willes , Luca A. Thiede , Anshul Kundaje , Alan Aspuru-Guzik

Aircraft aerodynamic design optimization must account for the varying operating conditions along the cruise segment as opposed to designing at one fixed operating condition, to arrive at more realistic designs. Conventional approaches…

Optimization and Control · Mathematics 2025-12-03 Kade Carlson , Ashwin Renganathan

Choices in scientific research and management require balancing multiple, often competing objectives.Multiple-objective optimization (MOO) provides a unifying framework for solving multiple objective problems. Model selection is a critical…

Applications · Statistics 2018-10-26 Perry Williams , William Kendall , Mevin Hooten

We present a preference learning framework for multiple criteria sorting. We consider sorting procedures applying an additive value model with diverse types of marginal value functions (including linear, piecewise-linear, splined, and…

Machine Learning · Computer Science 2019-10-15 Jiapeng Liu , Milosz Kadzinski , Xiuwu Liao , Xiaoxin Mao , Yao Wang

With modern requirements, there is an increasing tendency of considering multiple objectives/criteria simultaneously in many Software Engineering (SE) scenarios. Such a multi-objective optimization scenario comes with an important issue --…

Software Engineering · Computer Science 2020-12-01 Miqing Li , Tao Chen , Xin Yao

Multi-component self-assembly mixtures offer the possibility of encoding multiple target structures with the same set of interacting components. Selective retrieval of one of the stored structures has been attempted by preparing an initial…

Soft Condensed Matter · Physics 2022-03-23 Arunkumar Bupathy , Daan Frenkel , Srikanth Sastry

The data made available for analysis are becoming more and more complex along several directions: high dimensionality, number of examples and the amount of labels per example. This poses a variety of challenges for the existing machine…

Machine Learning · Computer Science 2020-08-11 Matej Petković , Sašo Džeroski , Dragi Kocev

The article presents a study on the biobjective inventory routing problem. Contrary to most previous research, the problem is treated as a true multi-objective optimization problem, with the goal of identifying Pareto-optimal solutions. Due…

Artificial Intelligence · Computer Science 2011-09-15 Martin Josef Geiger , Marc Sevaux

Experimentation is an essential method for causal inference in any empirical discipline. Crossover-design experiments are common in Software Engineering (SE) research. In these, subjects apply more than one treatment in different orders.…

Software Engineering · Computer Science 2025-01-08 Julian Frattini , Davide Fucci , Sira Vegas

Basket designs are prospective clinical trials that are devised with the hypothesis that the presence of selected molecular features determine a patient's subsequent response to a particular "targeted" treatment strategy. Basket trials are…

Computation · Statistics 2019-08-05 Michael J. Kane , Nan Chen , Alexander M. Kaizer , Xun Jiang , H. Amy Xia , Brian P. Hobbs

AI foundation models have the capability to produce a wide array of responses to a single prompt, a feature that is highly beneficial in software engineering to generate diverse code solutions. However, this advantage introduces a…

Software Engineering · Computer Science 2024-03-21 Scott Blyth , Markus Wagner , Christoph Treude

Mixed methods research is often used in software engineering, but researchers outside of the social or human sciences often lack experience when using these designs. This paper provides guiding principles and advice on how to design mixed…

Software Engineering · Computer Science 2025-03-26 Margaret-Anne Storey , Rashina Hoda , Alessandra Maciel Paz Milani , Maria Teresa Baldassarre

A hybrid model involves the cooperation of an interpretable model and a complex black box. At inference, any input of the hybrid model is assigned to either its interpretable or complex component based on a gating mechanism. The advantages…

Machine Learning · Computer Science 2023-03-09 Julien Ferry , Gabriel Laberge , Ulrich Aïvodji
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