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Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel treatment that delivers radiation in pulses of protracted intervals. Accurate prediction of gross tumor volume (GTV) changes through regression models…

Machine Learning · Computer Science 2025-09-18 Yajun Yu , Steve Jiang , Robert Timmerman , Hao Peng

Glioblastoma Multiforme (GBM) is an aggressive form of malignant brain tumor with a generally poor prognosis. Treatment usually includes a mix of surgical resection, radiation therapy, and akylating chemotherapy but, even with these…

Medical Physics · Physics 2024-01-11 Erich Schmitz , Yunhui Guo , Jing Wang

Although the Gradient Boosted Decision Trees (GBDTs) dominate industrial tabular applications, upgrading legacy models in high-concurrency production environments still faces prohibitive retraining costs and systemic risks. To address this…

Artificial Intelligence · Computer Science 2026-05-26 Ziming Dai , Dabiao Ma , Jinle Tong , Mengyuan Han , Jian Yang , Hongtao Liu , Haojun Fei , Qing Yang

Objective: Brain networks have gained increasing recognition as potential biomarkers in mental health studies, but there are limited approaches that can leverage complex brain networks for accurate classification. Our goal is to develop a…

Methodology · Statistics 2022-05-25 Jin Ming , Suprateek Kundu

Support vector machine modeling is a new approach in machine learning for classification showing good performance on forecasting problems of small samples and high dimensions. Later, it promoted to Support Vector Regression (SVR) for…

Machine Learning · Computer Science 2021-03-23 Mohammadreza Ghanbari , Mahdi Goldani

Support Vector Machines (SVMs) were primarily designed for 2-class classification. But they have been extended for N-class classification also based on the requirement of multiclasses in the practical applications. Although N-class…

Machine Learning · Computer Science 2015-12-03 Aruna Govada , Bhavul Gauri , S. K. Sahay

This paper proposes a hybrid framework combining LSTM (Long Short-Term Memory) networks with LightGBM and CatBoost for stock price prediction. The framework processes time-series financial data and evaluates performance using seven models:…

Machine Learning · Computer Science 2025-05-30 Chang Yu , Fang Liu , Jie Zhu , Shaobo Guo , Yifan Gao , Zhongheng Yang , Meiwei Liu , Qianwen Xing

Support vector regression (SVR) has been widely used to reduce the high computational cost of computer simulation. SVR assumes the input parameters have equal sample sizes, but unequal sample sizes are often encountered in engineering…

Signal Processing · Electrical Eng. & Systems 2021-11-09 Maolin Shi , Wei Sun , Xueguan Song , Hongyou Li

Support vector machines (SVMs) are an extremely successful type of classification and regression algorithms. Building an SVM entails solving a constrained convex quadratic programming problem, which is quadratic in the number of training…

Machine Learning · Computer Science 2008-11-15 Danny Bickson , Elad Yom-Tov , Danny Dolev

Modern neural network architectures have achieved remarkable accuracies but remain highly dependent on their training data, often lacking interpretability in their learned mappings. While effective on large datasets, they tend to overfit on…

Machine Learning · Computer Science 2025-03-19 Pavia Bera , Sanjukta Bhanja

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Genomics · Quantitative Biology 2013-05-28 Yupeng Cun , Holger Fröhlich

Using predictive models to identify patterns that can act as biomarkers for different neuropathoglogical conditions is becoming highly prevalent. In this paper, we consider the problem of Autism Spectrum Disorder (ASD) classification where…

Machine Learning · Statistics 2018-10-31 Rushil Anirudh , Jayaraman J. Thiagarajan

Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

The support vector machines (SVM) is one of the most widely used and practical optimization based classification models in machine learning because of its interpretability and flexibility to produce high quality results. However, the big…

Machine Learning · Computer Science 2020-11-06 Ehsan Sadrfaridpour , Korey Palmer , Ilya Safro

In the era of big data, an important weapon in a machine learning researcher's arsenal is a scalable Support Vector Machine (SVM) algorithm. SVMs are extensively used for solving classification problems. Traditional algorithms for learning…

Machine Learning · Computer Science 2018-12-07 Haimonti Dutta , Nitin Nataraj

Gradient Boosted Decision Tree (GBDT) is a widely-used machine learning algorithm that has been shown to achieve state-of-the-art results on many standard data science problems. We are interested in its application to multioutput problems…

Machine Learning · Computer Science 2022-11-24 Leonid Iosipoi , Anton Vakhrushev

We consider applying Bayesian Variable Selection Regression, or BVSR, to genome-wide association studies and similar large-scale regression problems. Currently, typical genome-wide association studies measure hundreds of thousands, or…

Applications · Statistics 2011-10-28 Yongtao Guan , Matthew Stephens

Autism Spectrum Disorder (ASD) is on the rise and constantly growing. Earlier identify of ASD with the best outcome will allow someone to be safe and healthy by proper nursing. Humans can hardly estimate the present condition and stage of…

Machine Learning · Computer Science 2021-01-28 Koushik Chowdhury , Mir Ahmad Iraj

Applications of machine learning (ML) techniques to operational settings often face two challenges: i) ML methods mostly provide point predictions whereas many operational problems require distributional information; and ii) They typically…

Machine Learning · Computer Science 2024-08-05 Ragip Gurlek , Francis de Vericourt , Donald K. K. Lee