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Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Multimodal sentiment analysis (MSA) is a fundamental complex research problem due to the heterogeneity gap between different modalities and the ambiguity of human emotional expression. Although there have been many successful attempts to…

Machine Learning · Computer Science 2022-07-05 Jiahao Zheng , Sen Zhang , Xiaoping Wang , Zhigang Zeng

Enhancing accurate molecular property prediction relies on effective and proficient representation learning. It is crucial to incorporate diverse molecular relationships characterized by multi-similarity (self-similarity and relative…

Machine Learning · Computer Science 2024-02-05 Hao Xu , Zhengyang Zhou , Pengyu Hong

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Recent advancements in multi-modal large language models have propelled the development of joint probabilistic models capable of both image understanding and generation. However, we have identified that recent methods suffer from loss of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Jian Yang , Dacheng Yin , Yizhou Zhou , Fengyun Rao , Wei Zhai , Yang Cao , Zheng-Jun Zha

Accurate molecular property prediction (MPP) is a critical step in modern drug development. However, the scarcity of experimental validation data poses a significant challenge to AI-driven research paradigms. Under few-shot learning…

Machine Learning · Computer Science 2025-05-20 Yifan Dai , Xuanbai Ren , Tengfei Ma , Qipeng Yan , Yiping Liu , Yuansheng Liu , Xiangxiang Zeng

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yuxiang Luo , Qing Xu , Hai Huang , Yuqi Ouyang , Zhen Chen , Wenting Duan

We consider the problem of referring image segmentation. Given an input image and a natural language expression, the goal is to segment the object referred by the language expression in the image. Existing works in this area treat the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-10 Linwei Ye , Mrigank Rochan , Zhi Liu , Yang Wang

Graph Neural Networks (GNNs) have been widely employed for feature representation learning in molecular graphs. Therefore, it is crucial to enhance the expressiveness of feature representation to ensure the effectiveness of GNNs. However, a…

Machine Learning · Computer Science 2024-09-16 Chengyu Yao , Hong Huang , Hang Gao , Fengge Wu , Haiming Chen , Junsuo Zhao

Molecular representation learning is pivotal in predicting molecular properties and advancing drug design. Traditional methodologies, which predominantly rely on homogeneous graph encoding, are limited by their inability to integrate…

Machine Learning · Computer Science 2025-03-24 Mukun Chen , Jia Wu , Shirui Pan , Fu Lin , Bo Du , Xiuwen Gong , Wenbin Hu

Materials science datasets are inherently heterogeneous and are available in different modalities such as characterization spectra, atomic structures, microscopic images, and text-based synthesis conditions. The advancements in multi-modal…

Machine Learning · Computer Science 2024-11-14 Janghoon Ock , Joseph Montoya , Daniel Schweigert , Linda Hung , Santosh K. Suram , Weike Ye

A comprehensive understanding of molecular structures is important for the prediction of molecular ground-state conformation involving property information. Meanwhile, state space model (e.g., Mamba) has recently emerged as a promising…

Chemical Physics · Physics 2025-11-14 Yuxin Gou , Aming Wu , Richang Hong , Meng Wang

We introduce CLARGA, a general-purpose multimodal fusion architecture for multimodal representation learning that works with any number and type of modalities without changing the underlying framework. Given a supervised dataset, CLARGA can…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Santosh Patapati

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Molecule and text representation learning has gained increasing interest due to its potential for enhancing the understanding of chemical information. However, existing models often struggle to capture subtle differences between molecules…

Machine Learning · Computer Science 2025-10-31 Hyuntae Park , Yeachan Kim , SangKeun Lee

Developing effective path representations has become increasingly essential across various fields within intelligent transportation. Although pre-trained path representation learning models have shown improved performance, they…

Machine Learning · Computer Science 2025-01-03 Ronghui Xu , Hanyin Cheng , Chenjuan Guo , Hongfan Gao , Jilin Hu , Sean Bin Yang , Bin Yang

Multimodal embedding models, built upon causal Vision Language Models (VLMs), have shown promise in various tasks. However, current approaches face three key limitations: the use of causal attention in VLM backbones is suboptimal for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Haonan Chen , Hong Liu , Yuping Luo , Liang Wang , Nan Yang , Furu Wei , Zhicheng Dou

Multimodal datasets contain an enormous amount of relational information, which grows exponentially with the introduction of new modalities. Learning representations in such a scenario is inherently complex due to the presence of multiple…

Machine Learning · Computer Science 2019-09-24 Devanshu Arya , Stevan Rudinac , Marcel Worring

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

This paper presents a novel generative framework for learning shared latent representations across multimodal data. Many advanced multimodal methods focus on capturing all combinations of modality-specific details across inputs, which can…

Machine Learning · Computer Science 2025-08-26 Jiali Cui , Yan-Ying Chen , Yanxia Zhang , Matthew Klenk
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