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Image enhancement approaches often assume that the noise is signal independent, and approximate the degradation model as zero-mean additive Gaussian. However, this assumption does not hold for biomedical imaging systems where sensor-based…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Calvin-Khang Ta , Abhishek Aich , Akash Gupta , Amit K. Roy-Chowdhury

High-resolution electron microscopy (HREM) imaging technique is a powerful tool for directly visualizing a broad range of materials in real-space. However, it faces challenges in denoising due to ultra-low signal-to-noise ratio (SNR) and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Xuanyu Tian , Zhuoya Dong , Xiyue Lin , Yue Gao , Hongjiang Wei , Yanhang Ma , Jingyi Yu , Yuyao Zhang

In the last several years deep learning based approaches have come to dominate many areas of computer vision, and image denoising is no exception. Neural networks can learn by example to map noisy images to clean images. However, access to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Jason Lequyer , Reuben Philip , Amit Sharma , Laurence Pelletier

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang

We develop Self2Seg, a self-supervised method for the joint segmentation and denoising of a single image. To this end, we combine the advantages of variational segmentation with self-supervised deep learning. One major benefit of our method…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Nadja Gruber , Johannes Schwab , Noémie Debroux , Nicolas Papadakis , Markus Haltmeier

Although the advances of self-supervised blind denoising are significantly superior to conventional approaches without clean supervision in synthetic noise scenarios, it shows poor quality in real-world images due to spatially correlated…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Kanggeun Lee , Kyungryun Lee , Won-Ki Jeong

Photon counting spectral CT (PCCT) can produce reconstructed attenuation maps in different energy channels, reflecting energy properties of the scanned object. Due to the limited photon numbers and the non-ideal detector response of each…

Image and Video Processing · Electrical Eng. & Systems 2022-01-27 Chaoyang Zhang , Shaojie Chang , Ti Bai , Xi Chen

This paper proposes a novel method for automatic MRI denoising that exploits last advances in deep learning feature regression and self-similarity properties of the MR images. The proposed method is a two-stage approach. In the first stage,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Jose V. Manjon , Pierrick Coupe

Recently, there has been extensive research interest in training deep networks to denoise images without clean reference. However, the representative approaches such as Noise2Noise, Noise2Void, Stein's unbiased risk estimator (SURE), etc.…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Kwanyoung Kim , Jong Chul Ye

Medical image denoising is considered among the most challenging vision tasks. Despite the real-world implications, existing denoising methods have notable drawbacks as they often generate visual artifacts when applied to heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 S M A Sharif , Rizwan Ali Naqvi , Woong-Kee Loh

Popular methods in compressed sensing (CS) are dependent on deep learning (DL), where large amounts of data are used to train non-linear reconstruction models. However, ensuring generalisability over and access to multiple datasets is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Marlon Bran Lorenzana , Feng Liu , Shekhar S. Chandra

The denoising of magnetic resonance (MR) images is a task of great importance for improving the acquired image quality. Many methods have been proposed in the literature to retrieve noise free images with good performances. Howerever, the…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Dongsheng Jiang , Weiqiang Dou , Luc Vosters , Xiayu Xu , Yue Sun , Tao Tan

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Dongkyu Won , Euijin Jung , Sion An , Philip Chikontwe , Sang Hyun Park

Fluorescence microscopy image (FMI) denoising faces critical challenges due to the compound mixed Poisson-Gaussian noise with strong spatial correlation and the impracticality of acquiring paired noisy/clean data in dynamic biomedical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-25 Jizhihui Liu , Qixun Teng , Qing Ma , Junjun Jiang

Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mohammed Alsubaie , Wenxi Liu , Linxia Gu , Ovidiu C. Andronesi , Sirani M. Perera , Xianqi Li

Deep learning has demonstrated strong potential for MRI reconstruction. However, conventional supervised learning requires high-quality, high-SNR references for network training, which are often difficult or impossible to obtain in…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Haoyang Pei , Nikola Janjuvsevic , Renqing Luo , Ding Xia , Xiang Xu , William Moore , Yao Wang , Hersh Chandarana , Li Feng

Image denoising is a fundamental task in computer vision, particularly in medical ultrasound (US) imaging, where speckle noise significantly degrades image quality. Although recent advancements in deep neural networks have led to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuesong Li , Nassir Navab , Zhongliang Jiang

Unsupervised denoising is a crucial challenge in real-world imaging applications. Unsupervised deep-learning methods have demonstrated impressive performance on benchmarks based on synthetic noise. However, no metrics are available to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Adria Marcos-Morales , Matan Leibovich , Sreyas Mohan , Joshua Lawrence Vincent , Piyush Haluai , Mai Tan , Peter Crozier , Carlos Fernandez-Granda

Real noisy-clean pairs on a large scale are costly and difficult to obtain. Meanwhile, supervised denoisers trained on synthetic data perform poorly in practice. Self-supervised denoisers, which learn only from single noisy images, solve…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Zejin Wang , Jiazheng Liu , Guoqing Li , Hua Han

Objective: Acquiring fully sampled training data is challenging for many MRI applications. We present a self-supervised image reconstruction method, termed ReSiDe, capable of recovering images solely from undersampled data. Materials and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Muhammad Shafique , Sizhuo Liu , Philip Schniter , Rizwan Ahmad