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Accurate interpretation of electrocardiogram (ECG) signals is crucial for diagnosing cardiovascular diseases. Recent multimodal approaches that integrate ECGs with accompanying clinical reports show strong potential, but they still face two…

Artificial Intelligence · Computer Science 2026-02-25 Ziwei Niu , Hao Sun , Shujun Bian , Xihong Yang , Lanfen Lin , Yuxin Liu , Yueming Jin

Biomedical signal processing extract meaningful information from physiological signals like electrocardiograms (ECGs), electroencephalograms (EEGs), and electromyograms (EMGs) to diagnose, monitor, and treat medical conditions and diseases…

Signal Processing · Electrical Eng. & Systems 2025-08-13 Justin London

Antibody co-design represents a critical frontier in drug development, where accurate prediction of both 1D sequence and 3D structure of complementarity-determining regions (CDRs) is essential for targeting specific epitopes. Despite recent…

Biomolecules · Quantitative Biology 2025-02-27 Jiayang Wu , Xingyi Zhang , Xiangyu Dong , Kun Xie , Ziqi Liu , Wensheng Gan , Sibo Wang , Le Song

Objective: To develop and interpret a supervised variational autoencoder (VAE) model for classifying cardiotocography (CTG) signals based on pregnancy outcomes, addressing interpretability limits of current deep learning approaches.…

Machine Learning · Computer Science 2025-09-09 John Tolladay , Beth Albert , Gabriel Davis Jones

Deep learning has been widely applied to 3D medical image segmentation tasks. However, due to the diversity of imaging modalities, the high-dimensional nature of the data, and the heterogeneity of anatomical structures, achieving both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Chung-Ming Lo , I-Yun Liu , Wei-Yang Lin

Remote monitoring of cardiovascular diseases plays an essential role in early detection of abnormal cardiac function, enabling timely intervention, improved preventive care, and personalized patient treatment. Abnormalities in the heart…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-07 Vladimir Despotovic , Peter Pocta , Andrej Zgank

Objective: Global (inter-patient) ECG classification for arrhythmia detection over Electrocardiogram (ECG) signal is a challenging task for both humans and machines. The main reason is the significant variations of both normal and…

Machine Learning · Computer Science 2022-05-31 Muhammad Uzair Zahid , Serkan Kiranyaz , Moncef Gabbouj

The electrocardiogram (ECG) is routinely used in hospitals to analyze cardiovascular status and health of an individual. Abnormal heart rhythms can be a precursor to more serious conditions including sudden cardiac death. Classifying…

Signal Processing · Electrical Eng. & Systems 2022-07-15 Neville D. Gai

Electrocardiograms (ECGs) are essential for diagnosing cardiac pathologies, yet traditional paper-based ECG storage poses significant challenges for automated analysis. This study introduces ECGtizer, an open-source, fully automated tool…

Signal Processing · Electrical Eng. & Systems 2024-12-18 Alex Lence , Ahmad Fall , Samuel David Cohen , Federica Granese , Jean-Daniel Zucker , Joe-Elie Salem , Edi Prifti

Contemporary cardiovascular management involves complex consideration and integration of multimodal cardiac datasets, where each modality provides distinct but complementary physiological characteristics. While the effective integration of…

Electroencephalography signals (EEGs) contain rich multi-scale information crucial for understanding brain states, with potential applications in diagnosing and advancing the drug development landscape. However, extracting meaningful…

Machine Learning · Computer Science 2025-09-26 D. Darankoum , C. Habermacher , J. Volle , S. Grudinin

Multimodal deep learning foundation models can learn the relationship between images and text. In the context of medical imaging, mapping images to language concepts reflects the clinical task of diagnostic image interpretation, however…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Matthew Christensen , Milos Vukadinovic , Neal Yuan , David Ouyang

Focused transmits are the most commonly used transmit strategy for echocardiograms, but suffer from relatively low frame rates, and in 3D, even lower volume rates. Fast imaging based on unfocused transmits has disadvantages such as motion…

Signal Processing · Electrical Eng. & Systems 2026-05-14 Wessel L. van Nierop , Oisín Nolan , Tristan S. W. Stevens , Ruud J. G. van Sloun

We present CardiacGen, a Deep Learning framework for generating synthetic but physiologically plausible cardiac signals like ECG. Based on the physiology of cardiovascular system function, we propose a modular hierarchical generative model…

Machine Learning · Computer Science 2022-11-16 Tushar Agarwal , Emre Ertin

Classification and prediction of heart disease is a significant problem to realize medical treatment and life protection. In this paper, persistent homology is involved to analyze electrocardiograms and a novel heart disease classification…

Quantitative Methods · Quantitative Biology 2021-12-01 Yin Ni , Fupeng Sun , Yihao Luo , Zhengrui Xiang , Huafei Sun

Accurate classification of medical device risk levels is essential for regulatory oversight and clinical safety. We present a Transformer-based multimodal framework that integrates textual descriptions and visual information to predict…

Machine Learning · Computer Science 2025-05-02 Yu Han , Aaron Ceross , Jeroen H. M. Bergmann

We propose two deep neural network architectures for classification of arbitrary-length electrocardiogram (ECG) recordings and evaluate them on the atrial fibrillation (AF) classification data set provided by the PhysioNet/CinC Challenge…

Machine Learning · Computer Science 2018-04-10 Martin Zihlmann , Dmytro Perekrestenko , Michael Tschannen

The accurate segmentation of Coronary Computed Tomography Angiography (CCTA) images holds substantial clinical value for the early detection and treatment of Coronary Heart Disease (CHD). The Transformer, utilizing a self-attention…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Chenchu Xu , Meng Li , Xue Wu

Biomedical audio signals, such as phonocardiograms (PCG), are inherently rhythmic and contain diagnostic information in both their spectral (tonal) and temporal domains. Standard 2D spectrograms provide rich spectral features but compromise…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-30 Md. Saiful Bari Siddiqui , Utsab Saha

Myocardial infarction is a major cause of death globally, and accurate early diagnosis from electrocardiograms (ECGs) remains a clinical priority. Deep learning models have shown promise for automated ECG interpretation, but require large…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Lachin Naghashyar
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