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This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

Machine Learning · Computer Science 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

The rapid evolution of communication networks in recent decades has intensified the need for advanced Network and Service Management (NSM) strategies to address the growing demands for efficiency, scalability, enhanced performance, and…

Large Language Models (LLMs) have recently demonstrated impressive capabilities across various real-world applications. However, due to the current text-in-text-out paradigm, it remains challenging for LLMs to handle dynamic and complex…

Artificial Intelligence · Computer Science 2024-10-25 Timothy Wei , Annabelle Miin , Anastasia Miin

In this work, we propose a novel framework that integrates large language models (LLMs) with an RL-based dialogue manager for open-ended dialogue with a specific goal. By leveraging hierarchical reinforcement learning to model the…

Computation and Language · Computer Science 2025-07-09 Lucie Galland , Catherine Pelachaud , Florian Pecune

Conventional predictive modeling of parametric relationships in manufacturing processes is limited by the subjectivity of human expertise and intuition on the one hand and by the cost and time of experimental data generation on the other…

Computation and Language · Computer Science 2025-06-26 Kiarash Naghavi Khanghah , Anandkumar Patel , Rajiv Malhotra , Hongyi Xu

The research field of Information Retrieval (IR) has evolved significantly, expanding beyond traditional search to meet diverse user information needs. Recently, Large Language Models (LLMs) have demonstrated exceptional capabilities in…

Large language models (LLMs) are a class of language models that have demonstrated outstanding performance across a range of natural language processing (NLP) tasks and have become a highly sought-after research area, because of their…

Digital Libraries · Computer Science 2023-04-06 Lizhou Fan , Lingyao Li , Zihui Ma , Sanggyu Lee , Huizi Yu , Libby Hemphill

Conversational systems based on Large Language Models (LLMs), such as ChatGPT, show exceptional proficiency in context understanding and response generation. However, despite their impressive capabilities, they still possess limitations,…

Computation and Language · Computer Science 2023-10-17 Yang Deng , Lizi Liao , Liang Chen , Hongru Wang , Wenqiang Lei , Tat-Seng Chua

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

As organizations increasingly seek to leverage machine learning (ML) capabilities, the technical complexity of implementing ML solutions creates significant barriers to adoption and impacts operational efficiency. This research examines how…

Human-Computer Interaction · Computer Science 2025-07-09 Jiapeng Yao , Lantian Zhang , Jiping Huang

Large Language Models (LLMs) exhibit remarkable proficiency in addressing a diverse array of tasks within the Natural Language Processing (NLP) domain, with various prompt design strategies significantly augmenting their capabilities.…

Computation and Language · Computer Science 2024-08-05 Xiangyu Zhao , Chengqian Ma

This paper examines how large language models (LLMs) are transforming core quantitative methods in communication research in particular, and in the social sciences more broadly-namely, content analysis, survey research, and experimental…

Artificial Intelligence · Computer Science 2025-05-27 Tai-Quan Peng , Xuzhen Yang

With the rapid evolution of global autonomous driving technology, the demand for its core sensing hardware, Light Detection and Ranging (LiDAR), is escalating. As the light source part of the LiDAR system, lasers, particularly the…

The rapid rise of Large Language Models (LLMs) has created new disruptive possibilities for persuasive communication, enabling fully-automated, personalized, and interactive content generation at an unprecedented scale. In this paper, we…

Computation and Language · Computer Science 2026-04-22 Sander Noels , Alexander Rogiers , Maarten Buyl , Tijl De Bie

Large Language Models (LLMs) are conversational interfaces. As such, LLMs have the potential to assist their users not only when they can fully specify the task at hand, but also to help them define, explore, and refine what they need…

Computation and Language · Computer Science 2025-05-12 Philippe Laban , Hiroaki Hayashi , Yingbo Zhou , Jennifer Neville

In recent times, the grandeur of Large Language Models (LLMs) has not only shone in the realm of natural language processing but has also cast its brilliance across a vast array of applications. This remarkable display of LLM capabilities…

Computation and Language · Computer Science 2024-03-22 Hanieh Alipour , Nick Pendar , Kohinoor Roy

We propose the Single Conversation Methodology (SCM), a novel and pragmatic approach to software development using large language models (LLMs). In contrast to ad hoc interactions with generative AI, SCM emphasizes a structured and…

Software Engineering · Computer Science 2025-07-18 Salvador D. Escobedo

In complex engineering systems, the dependencies among components or development activities are often modeled and analyzed using Design Structure Matrix (DSM). Reorganizing elements within a DSM to minimize feedback loops and enhance…

Computational Engineering, Finance, and Science · Computer Science 2026-04-07 Shuo Jiang , Min Xie , Jianxi Luo

With the growing capabilities of large language models (LLMs), they are increasingly applied in areas like intelligent customer service, code generation, and knowledge management. Natural language (NL) prompts act as the ``APIs'' for…

Software Engineering · Computer Science 2025-08-12 Zhenchang Xing , Yang Liu , Zhuo Cheng , Qing Huang , Dehai Zhao , Daniel Sun , Chenhua Liu

Operations research (OR) is a core methodology that supports complex system decision-making, with broad applications in transportation, supply chain management, and production scheduling. However, traditional approaches that rely on…

Artificial Intelligence · Computer Science 2025-10-15 Yang Wang , Kai Li