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Quantile regression is useful for characterizing the conditional distribution of a response variable and understanding heterogeneity in the covariate effects at different quantiles. The rise of high-dimensional physiological data in…

Methodology · Statistics 2026-03-25 Yuanzhen Yue , Stella Self , Yichao Wu , Jiajia Zhang , Rahul Ghosal

Modern biomedical studies frequently collect complex, high-dimensional physiological signals using wearables and sensors along with time-to-event outcomes, making efficient variable selection methods crucial for interpretation and improving…

Methodology · Statistics 2026-04-22 Yuanzhen Yue , Stella Self , Yichao Wu , Jiajia Zhang , Rahul Ghosal

Recently, applied sciences, including longitudinal and clustered studies in biomedicine require the analysis of ultra-high dimensional linear mixed effects models where we need to select important fixed effect variables from a vast pool of…

Methodology · Statistics 2020-05-01 Abhik Ghosh , Magne Thoresen

In this paper, we present a general specification for Functional Effects Models, which use Machine Learning (ML) methodologies to learn individual-specific preference parameters from socio-demographic characteristics, therefore accounting…

Machine Learning · Statistics 2025-09-23 Nicolas Salvadé , Tim Hillel

With the rapid development of wearable device technologies, accelerometers can record minute-by-minute physical activity for consecutive days, which provides important insight into a dynamic association between the intensity of physical…

Methodology · Statistics 2024-09-06 Cheng Cao , Jiguo Cao , Hao Pan , Yunting Zhang , Fan Jiang , Xinyue Li

The functional linear model is a popular tool to investigate the relationship between a scalar/functional response variable and a scalar/functional covariate. We generalize this model to a functional linear mixed-effects model when repeated…

Methodology · Statistics 2016-01-07 Baisen Liu , Jiguo Cao

In this paper we propose a heterogeneous modeling framework which achieves individual-wise feature selection and individualized covariates' effects subgrouping simultaneously. In contrast to conventional model selection approaches, the new…

Methodology · Statistics 2019-06-11 Xiwei Tang , Fei Xue , Annie Qu

Longitudinal data analysis is fundamental for understanding dynamic processes in biomedical and social sciences. Although varying coefficient models (VCMs) provide a flexible framework by allowing covariate effects to evolve over time,…

Methodology · Statistics 2026-03-10 Yu Lu , Tianni Zhang , Yuyao Wang , Mengfei Ran

We consider joint selection of fixed and random effects in general mixed-effects models. The interpretation of estimated mixed-effects models is challenging since changing the structure of one set of effects can lead to different choices of…

Methodology · Statistics 2020-02-26 Maud Delattre , Marie-Anne Poursat

SEMMS (Scalable Empirical-Bayes Model for Marker Selection) is a variable-selection procedure for generalized linear models that uses a three-component normal mixture prior on regression coefficients. In its original form, SEMMS assumes…

Computation · Statistics 2026-03-18 Haim Bar , Martin T. Wells

In practical regression applications, multiple covariates are often measured, but not all may be associated with the response variable. Identifying and including only the relevant covariates in the model is crucial for improving prediction…

Methodology · Statistics 2026-03-10 Ana Carolina da Cruz , Camila P. E. de Souza , Pedro H. T. O. Sousa

High-dimensional variable selection, with many more covariates than observations, is widely documented in standard regression models, but there are still few tools to address it in non-linear mixed-effects models where data are collected…

Statistics Theory · Mathematics 2024-04-08 Marion Naveau , Guillaume Kon Kam King , Renaud Rincent , Laure Sansonnet , Maud Delattre

Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Methodology · Statistics 2026-01-19 Xiaojing Sun , Bingxin Zhao , Fei Xue

The bilevel functional data under consideration has two sources of repeated measurements. One is to densely and repeatedly measure a variable from each subject at a series of regular time/spatial points, which is named as functional data.…

Methodology · Statistics 2021-11-15 Xiaotian Dai , Guifang Fu

In the analysis of binary longitudinal data, it is of interest to model a dynamic relationship between a response and covariates as a function of time, while also investigating similar patterns of time-dependent interactions. We present a…

Methodology · Statistics 2023-04-11 Jinwon Sohn , Seonghyun Jeong , Young Min Cho , Taeyoung Park

Local variable selection aims to test for the effect of covariates on an outcome within specific regions. We outline a challenge that arises in the presence of non-linear effects and model misspecification. Specifically, for common…

Methodology · Statistics 2024-08-02 David Rossell , Arnold Kisuk Kseung , Ignacio Saez , Michele Guindani

In multi-condition EEG experiments, brain activity is recorded as subjects perform various tasks or are exposed to different stimuli. The recorded signals are commonly transformed into time-frequency representations, which often display…

Methodology · Statistics 2025-07-29 Xiaomeng Ju , Thaddeus Tarpey , Hyung G Park

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

Applications · Statistics 2013-05-27 Kosuke Imai , Marc Ratkovic

Functional mixed models are widely useful for regression analysis with dependent functional data, including longitudinal functional data with scalar predictors. However, existing algorithms for Bayesian inference with these models only…

Methodology · Statistics 2023-06-14 Thomas Y. Sun , Daniel R. Kowal

This paper is concerned with the selection and estimation of fixed and random effects in linear mixed effects models. We propose a class of nonconcave penalized profile likelihood methods for selecting and estimating important fixed…

Statistics Theory · Mathematics 2012-11-05 Yingying Fan , Runze Li
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