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Optical trapping has proven to be a valuable experimental technique for precisely controlling small dielectric objects. However, due to their very nature, conventional optical traps are diffraction limited and require high intensities to…

As free-space optical systems grow in scale and complexity, troubleshooting becomes increasingly time-consuming and, in the case of remote installations, perhaps impractical. An example of a task that is often laborious is the alignment of…

We report the realization of the first planar optical tweezer trap system by a sheet of light. To visualize the trapping of the target object (dielectric bead or live cell) in a plane, an orthogonal widefield detection is employed. The…

Optics · Physics 2024-04-17 Neptune Baro , Partha Pratim Mondal

Using optical tweezers and a haptic device, microspheres having diameters ranging from 3 to 4 um (floating in a fluid solution) are manipulated in order to form patterns of coupled optical microresonators by assembling the spheres via…

Optics · Physics 2007-07-24 Ibrahim Bukusoglu , Cagatay Basdogan , Alper Kiraz , Adnan Kurt

Advances in laser and optoelectronic technologies brought the general concept of optomechanical manipulation to the level of standard biophysical tools, paving ways towards controlled experiments and measurements of tiny mechanical forces.…

Optics · Physics 2021-06-30 Ivan Shishkin , Hen Markovich , Yael Roichman , Pavel Ginzburg

Microscopy, in particular scanning probe and electron microscopy, has been pivotal in improving our understanding of structure-function relationships at the nanoscale and is by now ubiquitous in most research characterization labs and…

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

Biomolecules · Quantitative Biology 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake

Holographic optical tweezers use computer-generated holograms to create arbitrary three-dimensional configurations of single-beam optical traps useful for capturing, moving and transforming mesoscopic objects. Through a combination of…

Soft Condensed Matter · Physics 2009-11-11 David G. Grier , Yael Roichman

Automating biological experimentation remains challenging due to the need for millimeter-scale precision, long and multi-step experiments, and the dynamic nature of living systems. Current liquid handlers only partially automate workflows,…

Scalability remains a major challenge in building practical fault-tolerant quantum computers. Currently, the largest number of qubits achieved across leading quantum platforms ranges from hundreds to thousands. In atom arrays, scalability…

It is common to introduce optical tweezers using either geometric optics for large particles or the Rayleigh approximation for very small particles. These approaches are successful at conveying the key ideas behind optical tweezers in their…

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-view, and phototoxicity. To overcome these limitations,…

Quantitative Methods · Quantitative Biology 2024-04-01 Leonor Morgado , Estibaliz Gómez-de-Mariscal , Hannah S. Heil , Ricardo Henriques

We experimentally demonstrate stable trapping and controlled manipulation of silica microspheres in a structured optical beam consisting of a dark focus surrounded by light in all directions - the so-called Dark Focus Tweezer. Results from…

Autonomous synthesis and characterization of inorganic materials requires the automatic and accurate analysis of X-ray diffraction spectra. For this task, we designed a probabilistic deep learning algorithm to identify complex multi-phase…

Materials Science · Physics 2021-05-27 Nathan J. Szymanski , Christopher J. Bartel , Yan Zeng , Qingsong Tu , Gerbrand Ceder

Robotic automation has transformed scientific workflows in domains such as chemistry and materials science, yet free-space optics, which is a high precision domain, remains largely manual. Optical systems impose strict spatial and angular…

Polyatomic molecules have rich structural features that make them uniquely suited to applications in quantum information science, quantum simulation, ultracold chemistry, and searches for physics beyond the Standard Model. However, a key…

Arrays of neutral atoms trapped in optical tweezers have emerged as a leading platform for quantum information processing and quantum simulation due to their scalability, reconfigurable connectivity, and high-fidelity operations. Individual…

Quantum Physics · Physics 2024-07-31 Shankar G. Menon , Noah Glachman , Matteo Pompili , Alan Dibos , Hannes Bernien

Neutral atoms trapped in microscopic optical tweezers have emerged as a growing platform for quantum science. Achieving homogeneity over the tweezers array is an important technical requirement, and our research focuses on improving it for…

The exponential growth of large-scale telescope arrays has boosted time-domain astronomy development but introduced operational bottlenecks, including labor-intensive observation planning, data processing, and real-time decision-making.…

Efficient loading of single atoms into tightly confined traps is crucial for advancing quantum information processing and exploring atom-photon interactions. However, directly loading atoms from a magneto-optical trap (MOT) into static…

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