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Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Nucleus segmentation is an important task in medical image analysis. However, machine learning models cannot perform well because there are large amount of clusters of crowded nuclei. To handle this problem, existing approaches typically…

Computer Vision and Pattern Recognition · Computer Science 2020-06-05 Shengcong Chen , Changxing Ding , Dacheng Tao

Automatic segmentation of breast tumors from the ultrasound images is essential for the subsequent clinical diagnosis and treatment plan. Although the existing deep learning-based methods have achieved significant progress in automatic…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Xing Yang , Jian Zhang , Qijian Chen , Li Wang , Lihui Wang

In this paper, we propose an automatic brain tumor segmentation approach (e.g., PixelNet) using a pixel-level convolutional neural network (CNN). The model extracts feature from multiple convolutional layers and concatenate them to form a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Mobarakol Islam , Hongliang Ren

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Instance segmentation is an important task for biomedical and biological image analysis. Due to the complicated background components, the high variability of object appearances, numerous overlapping objects, and ambiguous object…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Dongnan Liu , Donghao Zhang , Yang Song , Heng Huang , Weidong Cai

Image segmentation plays an essential role in nuclei image analysis. Recently, the segment anything model has made a significant breakthrough in such tasks. However, the current model exists two major issues for cell segmentation: (1) the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Qing Xu , Wenwei Kuang , Zeyu Zhang , Xueyao Bao , Haoran Chen , Wenting Duan

In computational pathology, nuclear instance segmentation is a fundamental task with many downstream clinical applications. With the advent of deep learning, many approaches, including convolutional neural networks (CNNs) and vision…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Amirreza Mahbod , Ramona Woitek , Jeanne Shen

Brain tumor classification is crucial for clinical analysis and an effective treatment plan to cure patients. Deep learning models help radiologists to accurately and efficiently analyze tumors without manual intervention. However, brain…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Mirza Mumtaz Zahoor , Saddam Hussain Khan

Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

In this paper, we propose a unified panoptic segmentation network (UPSNet) for tackling the newly proposed panoptic segmentation task. On top of a single backbone residual network, we first design a deformable convolution based semantic…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Yuwen Xiong , Renjie Liao , Hengshuang Zhao , Rui Hu , Min Bai , Ersin Yumer , Raquel Urtasun

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Accurate lesion segmentation in ultrasound images is essential for preventive screening and clinical diagnosis, yet remains challenging due to low contrast, blurry boundaries, and significant scale variations. Although existing deep…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Chen Wang , Yixin Zhu , Yongbin Zhu , Fengyuan Shi , Qi Li , Jun Wang , Zuozhu Liu , Keli Hu

Accurate segmentation of the tooth point cloud is of great significance for diagnosis clinical assisting and treatment planning. Existing methods mostly employ semantic segmentation, focusing on the semantic feature between different types…

Graphics · Computer Science 2026-01-01 Yating Cai , Yanghui Xu , Zehua Hu , Jiazhou Chen , Jing Huang

Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Liangrui Pan , Lian Wang , Zhichao Feng , Zhujun Xu , Liwen Xu , Shaoliang Peng

Previously, image interpretation in radiology relied heavily on manual methods. However, manual classification of brain tumor medical images is time-consuming and labor-intensive. Even with shallow convolutional neural network models, the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yufeng Li , Wenchao Zhao , Bo Dang , Weimin Wang

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Boundary incompleteness raises great challenges to automatic prostate segmentation in ultrasound images. Shape prior can provide strong guidance in estimating the missing boundary, but traditional shape models often suffer from hand-crafted…

Computer Vision and Pattern Recognition · Computer Science 2016-12-07 Xin Yang , Lequan Yu , Lingyun Wu , Yi Wang , Dong Ni , Jing Qin , Pheng-Ann Heng
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