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The escalating global mental health crisis, marked by persistent treatment gaps, availability, and a shortage of qualified therapists, positions Large Language Models (LLMs) as a promising avenue for scalable support. While LLMs offer…

Multimodal large language models (LLMs) are increasingly used to generate dermatology diagnostic narratives directly from images. However, reliable evaluation remains the primary bottleneck for responsible clinical deployment. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yuhao Shen , Jiahe Qian , Shuping Zhang , Zhangtianyi Chen , Tao Lu , Juexiao Zhou

The evolution of Large Language Models (LLMs) has showcased remarkable capacities for logical reasoning and natural language comprehension. These capabilities can be leveraged in solutions that semantically and textually model complex…

Human-Computer Interaction · Computer Science 2024-04-17 Syed Mekael Wasti , Ken Q. Pu , Ali Neshati

Large Language Models (LLMs) are increasingly deployed in healthcare, yet their communicative alignment with clinical standards remains insufficiently quantified. We conduct a multidimensional evaluation of general-purpose and…

Computation and Language · Computer Science 2026-04-23 Mariano Barone , Francesco Di Serio , Roberto Moio , Marco Postiglione , Giuseppe Riccio , Antonio Romano , Vincenzo Moscato

Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding…

Computation and Language · Computer Science 2025-11-04 He Hu , Yucheng Zhou , Juzheng Si , Qianning Wang , Hengheng Zhang , Fuji Ren , Fei Ma , Laizhong Cui , Qi Tian

This study validates Large Language Models (LLMs) as a dynamic alternative to questionnaire-based personality assessment. Using a within-subjects experiment (N=33), we compared Big Five personality scores derived from guided LLM…

Computation and Language · Computer Science 2026-02-19 Andrius Matšenas , Anet Lello , Tõnis Lees , Hans Peep , Kim Lilii Tamm

This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…

Cryptography and Security · Computer Science 2024-10-29 David Noever

Large Language Models (LLMs) offer a promising approach to enhancing Explainable AI (XAI) by transforming complex machine learning outputs into easy-to-understand narratives, making model predictions more accessible to users, and helping…

Artificial Intelligence · Computer Science 2025-04-02 Ahsan Bilal , David Ebert , Beiyu Lin

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

The widespread availability of Large Language Models (LLMs) within Integrated Development Environments (IDEs) has led to their speedy adoption. Conversational interactions with LLMs enable programmers to obtain natural language explanations…

Human-Computer Interaction · Computer Science 2024-02-12 Bhavya Chopra , Yasharth Bajpai , Param Biyani , Gustavo Soares , Arjun Radhakrishna , Chris Parnin , Sumit Gulwani

Multimodal Large Language Models (MLLMs) mimic human perception and reasoning system by integrating powerful Large Language Models (LLMs) with various modality encoders (e.g., vision, audio), positioning LLMs as the "brain" and various…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Jiaxing Huang , Jingyi Zhang

Audio-aware large language models (ALLMs) can understand the textual and non-textual information in the audio input. In this paper, we explore using ALLMs as an automatic judge to assess the speaking styles of speeches. We use ALLM judges…

Audio and Speech Processing · Electrical Eng. & Systems 2025-06-09 Cheng-Han Chiang , Xiaofei Wang , Chung-Ching Lin , Kevin Lin , Linjie Li , Radu Kopetz , Yao Qian , Zhendong Wang , Zhengyuan Yang , Hung-yi Lee , Lijuan Wang

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

Joint attention is a critical marker of early social-communicative development, yet remains difficult for caregivers to assess without expert guidance. In this work, we explore how multimodal large language models (MLLMs) can be aligned…

Human-Computer Interaction · Computer Science 2026-01-19 Weiyan Shi , Kenny Tsu Wei Choo

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

This study evaluates the GPT-4 Large Language Model's abductive reasoning in complex fields like medical diagnostics, criminology, and cosmology. Using an interactive interview format, the AI assistant demonstrated reliability in generating…

Artificial Intelligence · Computer Science 2023-07-21 Remo Pareschi

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Artificial Intelligence · Computer Science 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

Recent advances in large language models (LLMs) offer unprecedented opportunities to enhance human-AI collaboration in qualitative research methods, including interviews. While interviews are highly valued for gathering deep, contextualized…

Human-Computer Interaction · Computer Science 2025-04-22 Zhe Liu

Large Audio-Language Models (LALMs), such as GPT-4o, have recently unlocked audio dialogue capabilities, enabling direct spoken exchanges with humans. The potential of LALMs broadens their applicability across a wide range of practical…

Artificial Intelligence · Computer Science 2025-07-29 Kuofeng Gao , Shu-Tao Xia , Ke Xu , Philip Torr , Jindong Gu