English
Related papers

Related papers: Quantum QSAR for drug discovery

200 papers

Quantum computers promise to enhance machine learning for practical applications. Quantum machine learning for real-world data has to handle extensive amounts of high-dimensional data. However, conventional methods for measuring quantum…

Quantum Physics · Physics 2023-02-10 Tobias Haug , Chris N. Self , M. S. Kim

Quantum computing is expected to have transformative influences on many domains, but its practical deployments on industry problems are underexplored. We focus on applying quantum computing to operations management problems in industry, and…

Quantum Physics · Physics 2023-01-13 Hansheng Jiang , Zuo-Jun Max Shen , Junyu Liu

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

Aerodynamics plays an important role in aviation industry and aircraft design. Detecting and minimizing the phenomenon of flow separation from scattered pressure data on airfoil is critical for ensuring stable and efficient aviation.…

Quantum Physics · Physics 2024-08-22 Xi-Jun Yuan , Zi-Qiao Chen , Yu-Dan Liu , Zhe Xie , Xian-Min Jin , Ying-Zheng Liu , Xin Wen , Hao Tang

Quantum mechanics has introduced a new theoretical framework for the study of molecules, enabling the prediction of properties and dynamics through the solution of the Schr\"odinger equation applied to these systems. However, solving this…

The support vector machine (SVM) is a popular machine learning classification method which produces a nonlinear decision boundary in a feature space by constructing linear boundaries in a transformed Hilbert space. It is well known that…

Quantum Physics · Physics 2017-10-31 Rupak Chatterjee , Ting Yu

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

The Quantum Query Model is a framework that allows us to express most known quantum algorithms. Algorithms represented by this model consist on a set of unitary operators acting over a finite Hilbert space, and a final measurement step…

Quantum Physics · Physics 2018-03-22 S. A. Grillo , F. L. Marquezino

We present a computational platform for modeling chemical reactions in complex molecular environments, focused on ligand-protein binding in drug discovery. The platform implements our new quantum-in-quantum-in-classical (QM/QM/MM)…

Support vector machines (SVMs) are a well-established classifier effectively deployed in an array of pattern recognition and classification tasks. In this work, we consider extending classic SVMs with quantum kernels and applying them to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Artur Miroszewski , Jakub Mielczarek , Filip Szczepanek , Grzegorz Czelusta , Bartosz Grabowski , Bertrand Le Saux , Jakub Nalepa

Quantum machine learning is one of the fields where quantum computers are expected to bring advantages over classical methods. However, the limited size of current computers restricts the exploitation of the full potential of quantum…

Quantum Physics · Physics 2025-11-10 Juan C. Boschero , Ward van der Schoot , Niels M. P. Neumann

Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Since quantum systems produce counter-intuitive patterns believed not to be efficiently…

Quantum Physics · Physics 2018-05-14 Jacob Biamonte , Peter Wittek , Nicola Pancotti , Patrick Rebentrost , Nathan Wiebe , Seth Lloyd

Several proposals have been recently introduced to implement Quantum Machine Learning (QML) algorithms for the analysis of classical data sets employing variational learning means. There has been, however, a limited amount of work on the…

Quantum Physics · Physics 2022-10-04 Francesco Scala , Stefano Mangini , Chiara Macchiavello , Daniele Bajoni , Dario Gerace

While quantum machine learning (ML) has been proposed to be one of the most promising applications of quantum computing, how to build quantum ML models that outperform classical ML remains a major open question. Here, we demonstrate a…

Quantum Physics · Physics 2023-03-10 Elham Torabian , Roman V. Krems

The rapid advancement of quantum computing (QC) and machine learning (ML) has given rise to the burgeoning field of quantum machine learning (QML), aiming to capitalize on the strengths of quantum computing to propel ML forward. Despite its…

Quantum Physics · Physics 2024-07-30 Xin Dai , Tzu-Chieh Wei , Shinjae Yoo , Samuel Yen-Chi Chen

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

Quantum computing has opened new opportunities to tackle complex machine learning tasks, for instance, high-dimensional data representations commonly required in intelligent transportation systems. We explore quantum machine learning to…

Machine Learning · Computer Science 2025-09-09 Bara Rababah , Bilal Farooq

Quantum computers hold promise to enable efficient simulations of the properties of molecules and materials; however, at present they only permit ab initio calculations of a few atoms, due to a limited number of qubits. In order to harness…

Materials Science · Physics 2020-07-07 He Ma , Marco Govoni , Giulia Galli

Classical program analysis techniques, such as abstract interpretation and symbolic execution, are essential for ensuring software correctness, optimizing performance, and enabling compiler optimizations. However, these techniques face…

Quantum Physics · Physics 2025-10-14 Yicheng Guang , Pietro Zanotta , Kai Zhou , Yueqi Chen , Ramin Ayanzadeh

Despite the rapid and significant advancements in deep learning for Quantitative Structure-Activity Relationship (QSAR) models, the challenge of learning robust molecular representations that effectively generalize in real-world scenarios…

Machine Learning · Computer Science 2024-05-28 Jose Arjona-Medina , Ramil Nugmanov