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Related papers: CDE-Mapper: Using Retrieval-Augmented Language Mod…

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Common Data Elements (CDEs) standardize data collection and sharing across studies, enhancing data interoperability and improving research reproducibility. However, implementing CDEs presents challenges due to the broad range and variety of…

This research aims to develop a dynamic and scalable framework to facilitate harmonization of Common Data Elements (CDEs) across heterogeneous biomedical datasets by addressing challenges such as semantic heterogeneity, structural…

Information Retrieval · Computer Science 2025-06-04 Madan Krishnamurthy , Daniel Korn , Melissa A Haendel , Christopher J Mungall , Anne E Thessen

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Automatic ICD coding, the task of assigning disease and procedure codes to electronic medical records, is crucial for clinical documentation and billing. While existing methods primarily enhance model understanding of code hierarchies and…

Computation and Language · Computer Science 2025-11-11 Tuan-Dung Le , Shohreh Haddadan , Thanh Q. Thieu

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

This research combines Knowledge Distillation (KD) and Mixture of Experts (MoE) to develop modular, efficient multilingual language models. Key objectives include evaluating adaptive versus fixed alpha methods in KD and comparing modular…

Artificial Intelligence · Computer Science 2024-07-30 Mohammed Al-Maamari , Mehdi Ben Amor , Michael Granitzer

Retrieval augmented generation mitigates limitations of large language models in factual consistency and knowledge updating by introducing external knowledge. However, practical applications still suffer from semantic misalignment between…

Computation and Language · Computer Science 2026-03-06 Xin Chen , Saili Uday Gadgil , Jiarong Qiu

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Shibin Wu , Bang Yang , Zhiyu Ye , Haoqian Wang , Hairong Zheng , Tong Zhang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Knowledge Components (KCs) are foundational to adaptive learning systems, but their manual identification by domain experts is a significant bottleneck. While Large Language Models (LLMs) offer a promising avenue for automating this…

Computation and Language · Computer Science 2025-11-14 Canwen Wang , Jionghao Lin , Kenneth R. Koedinger

International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic…

Computation and Language · Computer Science 2022-02-22 Pavithra Rajendran , Alexandros Zenonos , Josh Spear , Rebecca Pope

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Data augmentation is a widely used strategy to improve model robustness and generalization by enriching training datasets with synthetic examples. While large language models (LLMs) have demonstrated strong generative capabilities for this…

Machine Learning · Computer Science 2025-09-29 Dongkyu Cho , Miao Zhang , Rumi Chunara

Patients with low health literacy usually have difficulty understanding medical jargon and the complex structure of professional medical language. Although some studies are proposed to automatically translate expert language into…

Computation and Language · Computer Science 2024-02-09 Junyu Luo , Zifei Zheng , Hanzhong Ye , Muchao Ye , Yaqing Wang , Quanzeng You , Cao Xiao , Fenglong Ma

Blended modeling is an emerging paradigm involving seamless interaction between multiple notations for the same underlying modeling language. We focus on a model-driven engineering (MDE) approach based on meta-models to develop textual…

Software Engineering · Computer Science 2024-01-31 Weixing Zhang

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

Domain experts across engineering, healthcare, and education follow strict standards for producing quality content such as technical manuals, medication instructions, and children's reading materials. However, current works in controllable…

Computation and Language · Computer Science 2024-10-07 Joseph Marvin Imperial , Gail Forey , Harish Tayyar Madabushi

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman
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