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One of the main goals of developmental biology is to reveal the gene regulatory networks (GRNs) underlying the robust differentiation of multipotent progenitors into precisely specified cell types. Most existing methods to infer GRNs from…

Quantitative Methods · Quantitative Biology 2024-01-23 Maria Mircea , Diego Garlaschelli , Stefan Semrau

Physics-informed neural networks (PINNs) impose known physical laws into the learning of deep neural networks, making sure they respect the physics of the process while decreasing the demand of labeled data. For systems represented by…

The integration of physics-based knowledge with machine learning models is increasingly shaping the monitoring, diagnostics, and prognostics of electrical transformers. In this two-part series, the first paper introduced the foundations of…

Machine Learning · Computer Science 2025-12-30 Jose I. Aizpurua

Physics-informed deep learning has drawn tremendous interest in recent years to solve computational physics problems, whose basic concept is to embed physical laws to constrain/inform neural networks, with the need of less data for training…

Fluid Dynamics · Physics 2020-11-24 Chengping Rao , Hao Sun , Yang Liu

In recent years, Physics-Informed Neural Networks (PINNs) have become a representative method for solving partial differential equations (PDEs) with neural networks. PINNs provide a novel approach to solving PDEs through optimization…

Computational Physics · Physics 2024-11-28 Weiwei Zhang , Wei Suo , Jiahao Song , Wenbo Cao

This study presents a novel physics-informed neural network (PINN) framework for modeling poroelasticity in heterogeneous media with material interfaces. The approach introduces a composite neural network (CoNN) where separate neural…

Systems and Control · Electrical Eng. & Systems 2024-12-31 Sumanta Roy , Chandrasekhar Annavarapu , Pratanu Roy , Dakshina Murthy Valiveti

Numerical modeling errors are unavoidable in finite element analysis. The presence of model errors inherently reflects both model accuracy and uncertainty. To date there have been few methods for explicitly quantifying errors at points of…

Machine Learning · Computer Science 2024-11-19 Bozhou Zhuang , Sashank Rana , Brandon Jones , Danny Smyl

In recent years, scientific machine learning, particularly physic-informed neural networks (PINNs), has introduced new innovative methods to understanding the differential equations that describe power system dynamics, providing a more…

Systems and Control · Electrical Eng. & Systems 2024-03-12 Huynh T. T. Tran , Hieu T. Nguyen

Achieving clean combustion systems is crucial in terms of solving environmental impacts, decarbonization needs and sustainability matters. Traditional combustion modeling techniques via computational fluid dynamics with accurate chemical…

Fluid Dynamics · Physics 2025-09-11 Mahmood Mousavi , Caleb Caldwell , Jacob Baltes , Muteb Aljasem , Bok Jik Lee

Physics-Informed Neural Networks (PINNs) have emerged as an influential technology, merging the swift and automated capabilities of machine learning with the precision and dependability of simulations grounded in theoretical physics. PINNs…

Physics-informed neural networks (PINNs) are a new tool for solving boundary value problems by defining loss functions of neural networks based on governing equations, boundary conditions, and initial conditions. Recent investigations have…

Computational Engineering, Finance, and Science · Computer Science 2023-11-14 Ali Harandi , Ahmad Moeineddin , Michael Kaliske , Stefanie Reese , Shahed Rezaei

Recent breakthroughs in computing power have made it feasible to use machine learning and deep learning to advance scientific computing in many fields, including fluid mechanics, solid mechanics, materials science, etc. Neural networks, in…

Physics-informed neural networks (PINNs) solve time-dependent partial differential equations (PDEs) by learning a mesh-free, differentiable solution that can be evaluated anywhere in space and time. However, standard space--time PINNs take…

Machine Learning · Computer Science 2026-01-29 Chen-Yang Dai , Che-Chia Chang , Te-Sheng Lin , Ming-Chih Lai , Chieh-Hsin Lai

Physics-Informed Neural Networks (PINNs) are Neural Network architectures trained to emulate solutions of differential equations without the necessity of solution data. They are currently ubiquitous in the scientific literature due to their…

Machine Learning · Computer Science 2023-08-25 Andrea Bonfanti , Roberto Santana , Marco Ellero , Babak Gholami

Physics-informed neural networks (PINNs) are a newly emerging research frontier in machine learning, which incorporate certain physical laws that govern a given data set, e.g., those described by partial differential equations (PDEs), into…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Bo Wang , A. K. Qin , Sajjad Shafiei , Hussein Dia , Adriana-Simona Mihaita , Hanna Grzybowska

Physics-informed Neural Networks (PINNs) have recently emerged as a principled way to include prior physical knowledge in form of partial differential equations (PDEs) into neural networks. Although PINNs are generally viewed as mesh-free,…

Machine Learning · Computer Science 2022-10-04 Fabricio Arend Torres , Marcello Massimo Negri , Monika Nagy-Huber , Maxim Samarin , Volker Roth

The transformative impact of machine learning, particularly Deep Learning (DL), on scientific and engineering domains is evident. In the context of computational fluid dynamics (CFD), Physics-Informed Neural Networks (PINNs) represent a…

Fluid Dynamics · Physics 2024-04-05 Siddharth Raghu , Rajdip Nayek , Vamsi Chalamalla

We develop a distributed framework for the physics-informed neural networks (PINNs) based on two recent extensions, namely conservative PINNs (cPINNs) and extended PINNs (XPINNs), which employ domain decomposition in space and in…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-09 Khemraj Shukla , Ameya D. Jagtap , George Em Karniadakis

Physics-informed neural networks (PINNs) [31] use automatic differentiation to solve partial differential equations (PDEs) by penalizing the PDE in the loss function at a random set of points in the domain of interest. Here, we develop a…

Neural and Evolutionary Computing · Computer Science 2019-12-03 E. Kharazmi , Z. Zhang , G. E. Karniadakis

Inverse problems arise almost everywhere in science and engineering where we need to infer on a quantity from indirect observation. The cases of medical, biomedical, and industrial imaging systems are the typical examples. A very high…

Machine Learning · Computer Science 2025-02-20 Ali Mohammad-Djafari