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Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Rosemary He , Gabriella Ang , Daniel Tward

Recent works have shown that deep neural networks can achieve super-human performance in a wide range of image classification tasks in the medical imaging domain. However, these works have primarily focused on classification accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Gongbo Liang , Yu Zhang , Xiaoqin Wang , Nathan Jacobs

Purpose: In many clinical MRI scenarios, existing imaging information can be used to significantly shorten acquisition time or to improve Signal to Noise Ratio (SNR). In this paper the authors present a framework for fast MRI by exploiting…

Medical Physics · Physics 2017-08-28 Lior Weizman , Yonina C. Eldar , Dafna Ben-Basaht

Diffusion-weighted magnetic resonance imaging (DW-MRI) derived scalar maps are effective for assessing neurodegenerative diseases and microstructural properties of white matter in large number of brain conditions. However, DW-MRI inherently…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Gabriel Girard , Manon Edde , Félix Dumais , Yoan David , Matthieu Dumont , Guillaume Theaud , Jean-Christophe Houde , Arnaud Boré , Maxime Descoteaux , Pierre-Marc Jodoin

The many successes of deep neural networks (DNNs) over the past decade have largely been driven by computational scale rather than insights from biological intelligence. Here, we explore if these trends have also carried concomitant…

Computer Vision and Pattern Recognition · Computer Science 2022-11-14 Thomas Fel , Ivan Felipe , Drew Linsley , Thomas Serre

Handwriting is significantly affected by neurological disorders (ND) such as Parkinson's disease (PD) and Alzheimer's disease (AD). Prior works have analyzed handwriting tasks using feature-based approaches or computer-vision techniques,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak , Thomas Thebaud

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

MRI images of the same subject in different contrasts contain shared information, such as the anatomical structure. Utilizing the redundant information amongst the contrasts to sub-sample and faithfully reconstruct multi-contrast images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Xinwen Liu , Jing Wang , Fangfang Tang , Shekhar S. Chandra , Feng Liu , Stuart Crozier

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Accuracy and consistency are two key factors in computer-assisted magnetic resonance (MR) image analysis. However, contrast variation from site to site caused by lack of standardization in MR acquisition impedes consistent measurements. In…

Image and Video Processing · Electrical Eng. & Systems 2021-03-25 Lianrui Zuo , Blake E. Dewey , Aaron Carass , Yihao Liu , Yufan He , Peter A. Calabresi , Jerry L. Prince

An important task in image processing and neuroimaging is to extract quantitative information from the acquired images in order to make observations about the presence of disease or markers of development in populations. Having a…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , Andrew J. Plassard , Larry T. Davis , Allen T. Newton , Susan M Resnick , Bennett A. Landman

Automatic image segmentation becomes very crucial for tumor detection in medical image processing.In general, manual and semi automatic segmentation techniques require more time and knowledge. However these drawbacks had overcome by…

Computer Vision and Pattern Recognition · Computer Science 2016-03-09 D. Anithadevi , K. Perumal

Neuroimage analysis usually involves learning thousands or even millions of variables using only a limited number of samples. In this regard, sparse models, e.g. the lasso, are applied to select the optimal features and achieve high…

Machine Learning · Computer Science 2015-03-26 Bo Xin , Lingjing Hu , Yizhou Wang , Wen Gao

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Functional MRI (fMRI) is crucial for studying brain function and diagnosing neurological disorders. However, existing analysis methods suffer from reproducibility and transferability challenges due to complex preprocessing pipelines and…

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Peirong Liu , Oula Puonti , Xiaoling Hu , Daniel C. Alexander , Juan E. Iglesias

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Objectives: High classification accuracy of Alzheimer's disease (AD) from structural MRI has been achieved using deep neural networks, yet the specific image features contributing to these decisions remain unclear. In this study, the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-20 Christian Tinauer , Maximilian Sackl , Rudolf Stollberger , Reinhold Schmidt , Stefan Ropele , Christian Langkammer

Image noise and motion artifacts greatly affect the quality of brain MRI and negatively influence downstream medical image analysis. Previous studies often focus on 2D methods that process each volumetric MR image slice-by-slice, thus…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Lintao Zhang , Mengqi Wu , Lihong Wang , David C. Steffens , Guy G. Potter , Mingxia Liu

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

Signal Processing · Electrical Eng. & Systems 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez
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