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We introduce a probabilistic model with implicit norm regularization for learning nonnegative matrix factorization (NMF) that is commonly used for predicting missing values and finding hidden patterns in the data, in which the matrix…

Machine Learning · Computer Science 2022-08-23 Jun Lu , Christine P. Chai

Magnetic resonance imaging (MRI) is the method of choice for noninvasive studies of micrometer-scale structures in biological tissues via their effects on the time/frequency-dependent ("restricted") and anisotropic self-diffusion of water.…

Soft Condensed Matter · Physics 2021-11-16 Omar Narvaez , Maxime Yon , Hong Jiang , Diana Bernin , Eva Forssell-Aronsson , Alejandra Sierra , Daniel Topgaard

Bayesian inference allows the transparent communication of uncertainty in material flow analyses (MFAs), and a systematic update of uncertainty as new data become available. However, the method is undermined by the difficultly of defining…

Applications · Statistics 2024-03-28 Jiayuan Dong , Jiankan Liao , Xun Huan , Daniel Cooper

Model-form uncertainties in complex mechanics systems are a major obstacle for predictive simulations. Reducing these uncertainties is critical for stake-holders to make risk-informed decisions based on numerical simulations. For example,…

Fluid Dynamics · Physics 2018-09-11 J. -L. Wu , J. -X. Wang , H. Xiao

We propose a novel framework for joint magnetic resonance image reconstruction and uncertainty quantification using under-sampled k-space measurements. The problem is formulated as a Bayesian linear inverse problem, where prior…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Ahmed Karam Eldaly , Matteo Figini , Daniel C. Alexander

Multi-modal Magnetic Resonance Imaging (MRI) translation leverages information from source MRI sequences to generate target modalities, enabling comprehensive diagnosis while overcoming the limitations of acquiring all sequences. While…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Jiyao Liu , Shangqi Gao , Yuxin Li , Lihao Liu , Xin Gao , Zhaohu Xing , Junzhi Ning , Yanzhou Su , Xiao-Yong Zhang , Junjun He , Ningsheng Xu , Xiahai Zhuang

We demonstrate the efficacy of symbolic regression (SR) to probe models of particle physics Beyond the Standard Model (BSM), by considering the so-called Constrained Minimal Supersymmetric Standard Model (CMSSM). Like many incarnations of…

High Energy Physics - Phenomenology · Physics 2025-10-24 Shehu AbdusSalam , Steven Abel , Deaglan Bartlett , Miguel Crispim Romão

Detecting and quantifying products of cellular metabolism using Mass Spectrometry (MS) has already shown great promise in many biological and biomedical applications. The biggest challenge in metabolomics is annotation, where measured…

Machine Learning · Computer Science 2020-10-12 Hao Zhu , Liping Liu , Soha Hassoun

Magnetic Resonance Fingerprinting (MRF) reconstructs tissue maps based on a sequence of very highly undersampled images. In order to be able to perform MRF reconstruction, state-of-the-art MRF methods rely on priors such as the MR physics…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Simon Arberet , Xiao Chen , Boris Mailhe , Peter Speier , Gregor Koerzdoerfer , Mathias Nittka , Heiko Meyer , Mariappan S. Nadar

We propose a new method to enforce priors on the solution of the nonnegative matrix factorization (NMF). The proposed algorithm can be used for denoising or single-channel source separation (SCSS) applications. The NMF solution is guided to…

Machine Learning · Computer Science 2013-03-01 Emad M. Grais , Hakan Erdogan

Stokes inversion techniques are very powerful methods for obtaining information on the thermodynamic and magnetic properties of solar and stellar atmospheres. In recent years, very sophisticated inversion codes have been developed that are…

Solar and Stellar Astrophysics · Physics 2022-03-23 C. J. Díaz Baso , A. Asensio Ramos , J. de la Cruz Rodríguez

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

In situ measurement of cellular metabolites is still a challenge in biology. Conventional methods, such as mass spectrometry or fluorescence microscopy, would either destruct the sample or introduce strong perturbations to the functions of…

Quantitative Methods · Quantitative Biology 2019-12-19 Kai-Chih Huang , Junjie Li , Chi Zhang , Yuying Tan , Ji-Xin Cheng

A central goal of modern magnetic resonance imaging (MRI) is to reduce the time required to produce high-quality images. Efforts have included hardware and software innovations such as parallel imaging, compressed sensing, and deep…

Medical Physics · Physics 2023-03-27 Yihong Xu , Chad W. Farris , Stephan W. Anderson , Xin Zhang , Keith A. Brown

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous,…

This work describes a Bayesian framework for reconstructing the boundaries that represent targeted features in an image, as well as the regularity (i.e., roughness vs. smoothness) of these boundaries.This regularity often carries crucial…

Numerical Analysis · Mathematics 2024-01-26 Babak Maboudi Afkham , Nicolai André Brogaard Riis , Yiqiu Dong , Per Christian Hansen

The next generation 21 cm surveys open a new window onto the early stages of cosmic structure formation and provide new insights about the Epoch of Reionization (EoR). However, the non-Gaussian nature of the 21 cm signal along with the huge…

Cosmology and Nongalactic Astrophysics · Physics 2020-09-18 Héctor J. Hortúa , Luigi Malago , Riccardo Volpi

Metabolic fluxes are the rates of life-sustaining chemical reactions within a cell and metabolites are the components. Determining the changes in these fluxes is crucial to understanding diseases with metabolic causes and consequences.…

Dynamical Systems · Mathematics 2024-07-15 Breanna Guppy , Colleen Mitchell , Eric Taylor

Neural networks are powerful function approximators with tremendous potential in learning complex distributions. However, they are prone to overfitting on spurious patterns. Bayesian inference provides a principled way to regularize neural…

Machine Learning · Computer Science 2024-12-02 Yanzhe Bekkemoen , Helge Langseth

Normalizing flows (NF) are a class of powerful generative models that have gained popularity in recent years due to their ability to model complex distributions with high flexibility and expressiveness. In this work, we introduce a new type…

Machine Learning · Computer Science 2023-06-08 Jonas Köhler , Michele Invernizzi , Pim de Haan , Frank Noé