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Many chirality-sensitive light-matter interactions are governed by chiral electron dynamics. Therefore, the development of advanced technologies harnessing chiral phenomena would critically benefit from measuring and controlling chiral…

We develop photoelectron interferometry based on laser-assisted extreme ultraviolet ionization for flexible and robust control of photoelectron circular dichroism in randomly oriented chiral molecules. A comb of XUV photons ionizes a sample…

Photoelectron circular dichroism (PECD) is a method where randomly oriented chiral molecules are photoionized due to irradiation by circularly-polarized lasers, yielding large chiral signals in the photoelectron momentum distribution.…

Optics · Physics 2025-12-16 Gal Bouskila , Avner Fleischer , Ofer Neufeld

Chiral light-matter interactions have been investigated for two centuries, leading to the discovery of many chiroptical processes used for discrimination of enantiomers. Whereas most chiroptical effects result from a response of bound…

Unravelling the main initial dynamics responsible for chiral recognition is a key stepin the understanding of many biological processes. However this challenging task requires a sensitive enantiospecic probe to investigate molecular…

Photoelectron circular dichroism (PECD) is a fascinating phenomenon both from a fundamental science aspect but also due to its emerging role as a highly sensitive analytic tool for chiral recognition in the gas phase. PECD has been studied…

Chemical Physics · Physics 2021-05-21 Alexander Kastner , Tom Ring , Hendrike Braun , Arne Senftleben , Thomas Baumert

Understanding the chirality of molecular reaction pathways is essential for a broad range of fundamental and applied sciences. However, the current ability to probe chirality on the time scale of chemical reactions remains very limited.…

Photoelectron circular dichroism (PECD) is a method whereby randomly oriented chiral molecules are irradiated by circularly-polarized light, photoionizing electrons, which are measured in a momentum-resolved manner. This scheme permits…

Chemical Physics · Physics 2025-05-23 Ofer Neufeld

Molecular chirality is a key design property for many technologies including bioresponsive imaging, circularly polarized light detection and emission, molecular motors and switches. Imaging and manipulating the primary steps of transient…

Spectroscopic techniques that are sensitive to molecular chirality are important analytical tools to quantitatively determine enantiomeric excess and purity of chiral molecular samples. Many chiroptical processes however produce weak…

Chemical Physics · Physics 2026-04-02 Sebastian Hartweg , Dusan k. Bozanic , Gustavo A. Garcia-Macias , Laurent Nahon

We report on a joint experimental and theoretical study of photoelectron circular dichroism (PECD) in methyloxirane. By detecting O 1s-photoelectrons in coincidence with fragment ions, we deduce the molecule's orientation and photoelectron…

In photoelectron circular dichroism (PECD) it is generally difficult to trace how and when the chirality of the molecule is imprinted onto the photoelectron. We present simulations of PECD in a simple model and employ chirality measures to…

Atomic Physics · Physics 2025-03-04 Marec W. Heger , Daniel M. Reich

Chiral molecules are instrumental for molecular recognition in living organisms. Distinguishing between two opposite enantiomers, the mirror twins of the same chiral molecule, is both vital and challenging. Photoelectron circular dichroism…

Chemical Physics · Physics 2021-12-07 Andres F. Ordonez , David Ayuso , Piero Decleva , Olga Smirnova

The photoionization of chiral molecules prepared in a coherent superposition of excited states can give access to the underlying chiral coherent dynamics in a procedure known as photoexcitation induced photoelectron circular dichroism…

Atomic and Molecular Clusters · Physics 2018-08-29 Alex G Harvey , Zdeněk Mašín , Olga Smirnova

Chiral molecules are widespread in nature, playing a fundamental role in bio-chemical processes and in the origin of life itself. The observation of dynamics in chiral molecules is crucial for the understanding and control of the chiral…

Measuring and controlling the ionization dynamics by intense laser fields has recently led to important breakthroughs, from the investigation of tunneling time delays to attosecond molecular imaging by electron holography. In these…

We derive here a new highly selective photoelectron-based chirality-sensing technique that utilizes 'locally-chiral' laser pulses. We show that this approach results in strong chiral discrimination, where the standard forwards/backwards…

Chemical Physics · Physics 2021-07-14 Ofer Neufeld , Hannes Hübener , Angel Rubio , Umberto De Giovannini

Photoelectron circular dichroism (PECD) is a highly sensitive enantiospecific spectroscopy for studying chiral molecules in the gas phase using either single-photon ionization or multiphoton ionization. In the short pulse limit investigated…

We present a unique experimental design that enables the measurement of photoelectron circular dichroism (PECD) from chiral molecules in aqueous solution. The effect is revealed from the intensity difference of photoelectron emission into a…

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