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Related papers: Improving Omics-Based Classification: The Role of …

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Unbalanced tabular data sets present significant challenges for predictive modeling and data analysis across a wide range of applications. In many real-world scenarios, such as fraud detection, medical diagnosis, and rare event prediction,…

Machine Learning · Computer Science 2025-07-23 Ivona Krchova , Michael Platzer , Paul Tiwald

Deep neural networks are behind many of the recent successes in machine learning applications. However, these models can produce overconfident decisions while encountering out-of-distribution (OOD) examples or making a wrong prediction.…

Machine Learning · Computer Science 2021-06-24 Navid Kardan , Ankit Sharma , Kenneth O. Stanley

The reasoning capabilities of Large Language Models (LLMs) play a critical role in many downstream tasks, yet depend strongly on the quality of training data. Despite various proposed data construction methods, their practical utility in…

Computation and Language · Computer Science 2025-10-09 Yike Zhao , Simin Guo , Ziqing Yang , Shifan Han , Dahua Lin , Fei Tan

Synthetic data generation is increasingly used in machine learning for training and data augmentation. Yet, current strategies often rely on external foundation models or datasets, whose usage is restricted in many scenarios due to policy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Parsa Rahimi , Sebastien Marcel

It is more and more common to explore the genome at diverse levels and not only at a single omic level. Through integrative statistical methods, omics data have the power to reveal new biological processes, potential biomarkers, and…

Methodology · Statistics 2021-03-05 Morgane Pierre-Jean , Florence Mauger , Jean-François Deleuze , Edith Le Floch

Today, machine learning is applied in almost any field. In machine learning, where there are numerous methods, classification is one of the most basic and crucial ones. Various problems can be solved by classification. The feature selection…

Machine Learning · Computer Science 2022-07-01 Ahmet Tuğrul Bayrak

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

High-dimensional regression specification and analysis is a complex and active area of research in statistics, machine learning, and econometrics. This paper proposes a new approach, Boosting with Multiple Testing (BMT), which combines…

Econometrics · Economics 2026-02-24 George Kapetanios , Vasilis Sarafidis , Alexia Ventouri

There are many issues that can cause problems when attempting to infer model parameters from data. Data and models are both imperfect, and as such there are multiple scenarios in which standard methods of inference will lead to misleading…

Computation · Statistics 2024-05-01 Simon L. Cotter

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

Machine Learning · Computer Science 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

In the integrative analyses of omics data, it is often of interest to extract data representation from one data type that best reflect its relations with another data type. This task is traditionally fulfilled by linear methods such as…

Applications · Statistics 2021-03-30 Tianwei Yu

Being able to interpret, or explain, the predictions made by a machine learning model is of fundamental importance. This is especially true when there is interest in deploying data-driven models to make high-stakes decisions, e.g. in…

Machine Learning · Computer Science 2019-10-01 An-phi Nguyen , María Rodríguez Martínez

Reliable medical image classification requires accurate predictions and well-calibrated uncertainty estimates, especially in high-stakes clinical settings. This work presents MedSymmFlow, a generative-discriminative hybrid model built on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Francisco Caetano , Lemar Abdi , Christiaan Viviers , Amaan Valiuddin , Fons van der Sommen

The integration of machine learning (ML) models enhances the efficiency, affordability, and reliability of feature detection in microscopy, yet their development and applicability are hindered by the dependency on scarce and often flawed…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Matthew J. Lynch , Ryan Jacobs , Gabriella Bruno , Priyam Patki , Dane Morgan , Kevin G. Field

In many studies of human diseases, multiple omic datasets are measured. Typically, these omic datasets are studied one by one with the disease, thus the relationship between omics are overlooked. Modeling the joint part of multiple omics…

Methodology · Statistics 2022-09-02 Zhujie Gu , Said el Bouhaddani , Jeanine Houwing-Duistermaat , Hae-Won Uh

The rapid advancement of generative models, such as Stable Diffusion, raises a key question: how can synthetic data from these models enhance predictive modeling? While they can generate vast amounts of datasets, only a subset meaningfully…

Machine Learning · Statistics 2025-05-09 Jialong Jiang , Wenkang Hu , Jian Huang , Yuling Jiao , Xu Liu

Managing the growing data from renewable energy production plants for effective decision-making often involves leveraging Ontology-based Data Access (OBDA), a well-established approach that facilitates querying diverse data through a shared…

Databases · Computer Science 2024-10-17 Marco Calautti , Damiano Duranti , Paolo Giorgini

Feature selection for predictive analytics is the problem of identifying a minimal-size subset of features that is maximally predictive of an outcome of interest. To apply to molecular data, feature selection algorithms need to be scalable…

Machine Learning · Statistics 2020-04-02 Michail Tsagris , Zacharias Papadovasilakis , Kleanthi Lakiotaki , Ioannis Tsamardinos