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Developing 3D vision-language models with robust clinical reasoning remains a challenge due to the inherent complexity of volumetric medical imaging, the tendency of models to overfit superficial report patterns, and the lack of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haoran Lai , Zihang Jiang , Kun Zhang , Qingsong Yao , Rongsheng Wang , Zhiyang He , Xiaodong Tao , Wei Wei , Shaohua Kevin Zhou

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jihyun Moon , Charmgil Hong

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Artificial Intelligence · Computer Science 2025-08-06 Mahtab Bigverdi , Wisdom Ikezogwo , Kevin Zhang , Hyewon Jeong , Mingyu Lu , Sungjae Cho , Linda Shapiro , Ranjay Krishna

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

Vision-Language Models (VLMs) facilitate medical visual question answering (MedVQA) by jointly interpreting images and text. However, existing models typically depend on large architectures and closed-set answers, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Jiayan Yang , Zhuoyu Wu , Wenqi Fang

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

Medical image representations can be learned through medical vision-language contrastive learning (mVLCL) where medical imaging reports are used as weak supervision through image-text alignment. These learned image representations can be…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Mingjian Li , Mingyuan Meng , Michael Fulham , David Dagan Feng , Lei Bi , Jinman Kim

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Shibin Wu , Bang Yang , Zhiyu Ye , Haoqian Wang , Hairong Zheng , Tong Zhang

Multimodal alignment between language and vision is the fundamental topic in current vision-language model research. Contrastive Captioners (CoCa), as a representative method, integrates Contrastive Language-Image Pretraining (CLIP) and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Ziping Ma , Furong Xu , Jian Liu , Ming Yang , Qingpei Guo

Vision-language models (VLMs) have achieved impressive progress in natural image reasoning, yet their potential in medical imaging remains underexplored. Medical vision-language tasks demand precise understanding and clinically coherent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yuxiang Lai , Jike Zhong , Ming Li , Shitian Zhao , Yuheng Li , Konstantinos Psounis , Xiaofeng Yang

Vision-Language Foundation Models (VLFM) have shown a tremendous increase in performance in terms of generating high-resolution, photorealistic natural images. While VLFMs show a rich understanding of semantic content across modalities,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Parham Saremi , Amar Kumar , Mohamed Mohamed , Zahra TehraniNasab , Tal Arbel

Multimodal large language models (MLLMs) have achieved significant success in the general field of image processing. Their emerging task generalization and freeform conversational capabilities can greatly facilitate medical diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Youzhu Jin , Yichen Zhang

Despite significant advancements in general AI, its effectiveness in the medical domain is limited by the lack of specialized medical knowledge. To address this, we formulate GMAI-VL-5.5M, a multimodal medical dataset created by converting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Tianbin Li , Yanzhou Su , Wei Li , Bin Fu , Zhe Chen , Ziyan Huang , Guoan Wang , Chenglong Ma , Ying Chen , Ming Hu , Yanjun Li , Pengcheng Chen , Xiaowei Hu , Zhongying Deng , Yuanfeng Ji , Jin Ye , Yu Qiao , Junjun He