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Mixed communities of organisms are found in many environments (from the human gut to marine ecosystems) and can have profound impact on human health and the environment. Metagenomics studies the genomic material of such communities through…

Genomics · Quantitative Biology 2021-12-23 Hansheng Xue , Vijini Mallawaarachchi , Yujia Zhang , Vaibhav Rajan , Yu Lin

Generative retrieval shed light on a new paradigm of document retrieval, aiming to directly generate the identifier of a relevant document for a query. While it takes advantage of bypassing the construction of auxiliary index structures,…

Information Retrieval · Computer Science 2025-06-03 Sunkyung Lee , Minjin Choi , Jongwuk Lee

In the field of functional genomics, the analysis of gene expression profiles through Machine and Deep Learning is increasingly providing meaningful insight into a number of diseases. The paper proposes a novel algorithm to perform Feature…

Genomics · Quantitative Biology 2023-03-31 Carlo Adornetto , Gianluigi Greco

Deep generative models provide powerful tools for distributions over complicated manifolds, such as those of natural images. But many of these methods, including generative adversarial networks (GANs), can be difficult to train, in part…

Machine Learning · Statistics 2017-11-08 Akash Srivastava , Lazar Valkov , Chris Russell , Michael U. Gutmann , Charles Sutton

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Feature selection aims to identify the optimal feature subset for enhancing downstream models. Effective feature selection can remove redundant features, save computational resources, accelerate the model learning process, and improve the…

Machine Learning · Computer Science 2024-12-19 Nanxu Gong , Wangyang Ying , Dongjie Wang , Yanjie Fu

Genomic data I used in many fields but, it has become known that most of the platforms used in the sequencing process produce significant errors. This means that the analysis and inferences generated from these data may have some errors…

Genomics · Quantitative Biology 2024-09-05 Ferdinand Kartriku , Robert Sowah , Charles Saah

Graph neural networks (GNNs) demonstrate a robust capability for representation learning on graphs with complex structures, showcasing superior performance in various applications. The majority of existing GNNs employ a graph convolution…

Machine Learning · Computer Science 2025-02-19 Jinlu Wang , Jipeng Guo , Yanfeng Sun , Junbin Gao , Shaofan Wang , Yachao Yang , Baocai Yin

We propose a Deep Texture Encoding Network (Deep-TEN) with a novel Encoding Layer integrated on top of convolutional layers, which ports the entire dictionary learning and encoding pipeline into a single model. Current methods build from…

Computer Vision and Pattern Recognition · Computer Science 2016-12-12 Hang Zhang , Jia Xue , Kristin Dana

Pre-trained code models lead the era of code intelligence, with multiple models designed with impressive performance. However, one important problem, data augmentation for code data that automatically helps developers prepare training data…

Software Engineering · Computer Science 2026-01-29 Zeming Dong , Qiang Hu , Xiaofei Xie , Maxime Cordy , Mike Papadakis , Yves Le Traon , Jianjun Zhao

Genetic Programming has been very successful in solving a large area of problems but its use as a machine learning algorithm has been limited so far. One of the reasons is the problem of overfitting which cannot be solved or suppresed as…

Neural and Evolutionary Computing · Computer Science 2015-05-05 Jan Žegklitz , Petr Pošík

Growing interest in modelling complex systems from brains to societies to cities using networks has led to increased efforts to describe generative processes that explain those networks. Recent successes in machine learning have prompted…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Govind Gandhi

Current approaches to genomic sequence modeling often struggle to align the inductive biases of machine learning models with the evolutionarily-informed structure of biological systems. To this end, we formulate a novel application of…

Machine Learning · Computer Science 2025-07-30 Raiyan R. Khan , Philippe Chlenski , Itsik Pe'er

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Auto-encoding generative adversarial networks (GANs) combine the standard GAN algorithm, which discriminates between real and model-generated data, with a reconstruction loss given by an auto-encoder. Such models aim to prevent mode…

Machine Learning · Statistics 2017-10-24 Mihaela Rosca , Balaji Lakshminarayanan , David Warde-Farley , Shakir Mohamed

Learning word representations has recently seen much success in computational linguistics. However, assuming sequences of word tokens as input to linguistic analysis is often unjustified. For many languages word segmentation is a…

Computation and Language · Computer Science 2013-09-19 Grzegorz Chrupała

We consider multi-solution optimization and generative models for the generation of diverse artifacts and the discovery of novel solutions. In cases where the domain's factors of variation are unknown or too complex to encode manually,…

Machine Learning · Computer Science 2021-05-11 Alexander Hagg , Sebastian Berns , Alexander Asteroth , Simon Colton , Thomas Bäck

Genome analysis fundamentally starts with a process known as read mapping, where sequenced fragments of an organism's genome are compared against a reference genome. Read mapping is currently a major bottleneck in the entire genome analysis…

Hardware Architecture · Computer Science 2020-10-29 Mohammed Alser , Zülal Bingöl , Damla Senol Cali , Jeremie Kim , Saugata Ghose , Can Alkan , Onur Mutlu

Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography. There are various methods that exist in other domains to detect hidden messages…

Machine Learning · Computer Science 2018-10-08 Ho Bae , Byunghan Lee , Sunyoung Kwon , Sungroh Yoon

Millions of repetitive code snippets are submitted to code repositories every day. To search from these large codebases using simple natural language queries would allow programmers to ideate, prototype, and develop easier and faster.…